How Lung Inflations Affect Blood Flow in ARDS
Part of Brain & nervous system, Lungs & breathing clinical trials.
This study looks at how inflating and deflating the lungs affects blood flow and heart function in people with severe lung injury (ARDS) who are on a breathing machine. It may help doctors find the best way to set the ventilator to protect your lungs and heart.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe breathing failure (ARDS) that started less than a week ago, often from pneumonia, infection, trauma, or shock.
- Your chest imaging shows cloudy areas in both lungs that aren't due to fluid or collapsed lung tissue.
- Your breathing problem is not mainly from heart failure or fluid overload.
- Your oxygen level in the blood is low (PaO2/FiO2 ratio of 200 or less) while on mechanical ventilation.
- You are 18 years old or older and not pregnant.
- You do not have a collapsed lung (pneumothorax), severe heart failure, or a pacemaker that prevents safe placement of monitoring equipment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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