Ketamine for treatment-resistant depression
Part of Brain & nervous system, Mental health clinical trials.
This study tests whether ketamine, given as a liquid under the tongue or swallowed, can help people with depression that hasn't improved with at least two other antidepressants. It aims to see if this treatment is safe and effective.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You weigh at least 110 pounds (50 kg).
- You have been diagnosed with major depressive disorder (moderate to severe).
- You are currently taking an antidepressant but it hasn't worked well enough after trying at least two different types.
- You have a responsible adult who can drive you home after treatment sessions.
- You are not pregnant or breastfeeding, and you have no active suicidal thoughts with a plan.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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