Ketamine for treatment-resistant depression
Part of Mental health clinical trials.
This trial tests if ketamine (taken as a pill or under the tongue) can help people with moderate to severe depression that hasn't improved with at least two other antidepressants. The goal is to find out if this approach is safe and effective.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You weigh 110 pounds (50 kg) or more.
- You have been diagnosed with moderate to severe major depression and are currently experiencing an episode.
- You are already taking medication for depression but it hasn't worked well enough after trying at least two different antidepressants.
- You have a adult who can accompany you or arrange safe travel after study visits.
- You are not actively suicidal, have serious medical conditions, or take medications that could interact with ketamine.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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