Study of an experimental drug for severe PMS (PMDD)
Part of Mental health clinical trials.
This study tests an experimental medicine for premenstrual dysphoric disorder (PMDD), a severe form of PMS. It is a phase 1 trial, so the main goal is to check the drug's safety and how your body handles it, but it may also help assess its effectiveness.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You were assigned female at birth, are between 18 and 50 years old, and are still having regular periods.
- You have a formal diagnosis of PMDD and have had at least one prior treatment for it under a doctor's care.
- You have a regular menstrual cycle lasting 24 to 35 days.
- You are using an acceptable form of birth control (like a copper IUD, low-dose hormonal IUD, or double-barrier methods) and have been for at least 8 weeks.
- You are not taking certain antidepressants (SSRIs) unless you've been on the same dose for at least 3 months and plan to continue.
- Your symptoms are severe enough as measured by standard scales, and you do not have other major mental health conditions or recent suicidal thoughts.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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