Antibody to prevent GVHD in half-matched stem cell transplant
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This study is testing whether giving a special antibody (anti-CD25) before a half-matched stem cell transplant can prevent a common side effect called graft-versus-host disease (GVHD), where donor cells attack your body. It is for people with blood cancers who are getting this type of transplant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a blood cancer, such as leukemia, lymphoma, or multiple myeloma.
- You will be receiving a stem cell transplant from a half-matched family donor (usually a parent, child, or sibling).
- You must be between 18 and 75 years old.
- You must agree to be randomly assigned to one of the treatment groups and follow the study schedule.
- You cannot have had a stem cell transplant before.
- You cannot be pregnant, breastfeeding, or planning to become pregnant during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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