Knee position and muscle loss during leg immobilization
Part of Bones, joints & muscles, Brain & nervous system clinical trials.
This study looks at how the position of your knee affects muscle loss when your leg is immobilized (kept still, like in a cast). It might help find ways to reduce muscle wasting when people can't move a limb.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a healthy adult between 18 and 40 years old.
- You are not a smoker.
- You do not have diabetes, heart disease, or high blood pressure.
- You are not taking any medications that affect muscle, except birth control.
- You have no history of blood clots, epilepsy, seizures, or schizophrenia.
- You do not have any known muscle disorders or severe kidney problems.
- You have not had a recent leg injury or fracture in the last 6 months.
- You are not currently doing intense resistance training more than 3 times a week.
- You are not allergic to lidocaine or amino acids.
- You have no metal implants or claustrophobia (fear of enclosed spaces) that would prevent an MRI.
- You are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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