Clin2
NCT07691307Likely a fitRecruiting

TruGamma tricuspid valve replacement study

Tricuspid Valve RegurgitationTricuspid Valve InsufficiencyTricuspid Valve Disease

Treatments studied

Part of Heart & circulation clinical trials.

This trial tests a new device called TruGamma to replace the tricuspid valve without open-heart surgery. It is for older adults with severe tricuspid regurgitation who cannot have surgery and still have symptoms despite medication.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
180 people
Ages
65 years and older
Study type
Interventional

Who can take part

  • You must be 65 years or older.
  • You have severe tricuspid regurgitation (a leaky heart valve) that causes symptoms like shortness of breath or swelling, even with medicines.
  • Your heart failure symptoms are significant (Class III or IV), meaning you feel very short of breath even with mild activity or at rest.
  • Your heart team has determined you are not a candidate for open-heart surgery.
  • You are willing and able to follow all study procedures and give written consent.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04436653Recruiting
New valve procedure for severe right-sided leakage

This trial tests whether a new minimally invasive valve replacement device (put through a catheter) can improve health in people with severe right-sided tricuspid valve leaking. It’s for patients who are considered too high-risk for standard open-heart tricuspid surgery.

Beijing, Beijing Municipality
NCT07516444Recruiting
Tricuspid valve replacement using a new catheter device

This trial tests a new device that replaces a leaky tricuspid valve (a heart valve) without open-heart surgery. If your tricuspid valve isn't working well and medicines haven't helped enough, this procedure might improve your heart function and symptoms.

Minneapolis, Minnesota
NCT07687485Not yet recruiting
Trial of a new valve for severe tricuspid regurgitation

This trial tests a new device, called the Laplace TTVR System, to replace the tricuspid valve in people whose leaky valve (tricuspid regurgitation) continues to cause symptoms despite medical treatment. It may help if you have severe symptoms and are not a candidate for open-heart surgery.

NCT06458907Not yet recruiting
New valve device for severe tricuspid regurgitation

This trial tests a new, less invasive valve device (TricValve) for people with severe tricuspid regurgitation who are not good candidates for open-heart surgery. It aims to see if this device can help your heart pump better and improve your symptoms.

Birmingham, Alabama
NCT06581471Recruiting
New device for severe leaky heart valve

This study tests a new device to fix a leaky tricuspid valve without open-heart surgery. It is for people with severe leakage who are considered too high-risk for traditional surgery.

Aalst
NCT04097145Recruiting
Heart valve repair for severe leaking tricuspid valve

This trial tests a catheter-based procedure (done through the blood vessels) to repair a severely leaky tricuspid valve. It may help people with symptoms or past hospitalizations from tricuspid valve leakage who are higher-risk for standard surgery.

Phoenix, Arizona

Hear when a new Tricuspid Valve Regurgitation trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.