Depemokimab for chronic sinusitis with nasal polyps
Treatments studied
Part of Ear, nose & throat, Lungs & breathing clinical trials.
This trial tests a new antibody medicine (depemokimab) for Japanese adults with chronic sinusitis and nasal polyps. It aims to see if the drug alone can reduce symptoms without needing steroid nasal sprays.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older
- You have had nasal polyps for at least 12 weeks with symptoms like blockage, runny nose, or loss of smell
- Your polyps must be visible on both sides of your nose and score at least 5 on a severity scale
- You have either had polyp surgery before, needed steroid pills in the last 2 years, or can't take steroids
- You have not used steroid nasal sprays or washes for at least 8 weeks before the study starts
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares three different biologic medications (injectable drugs) to see which one works best for people with chronic sinusitis and nasal polyps. If you have moderate to severe symptoms and are considering biologic therapy, this study might help find the best option for you.
This study follows patients in France who are receiving biologic treatments for severe nasal polyps with chronic sinusitis. It collects information on how well these treatments work and their side effects over time.
This study tests an experimental medication called felcorekibart, given as an injection, to see if it reduces nasal polyps and improves sinus symptoms like congestion and loss of smell. It is for adults who have had nasal polyps for at least a year and have already tried standard treatments like steroid sprays or pills, or had surgery.
This study tests a new medication called felcorekibart for people with chronic sinusitis and nasal polyps. It may help reduce symptoms like congestion and loss of smell.
This study looks at how well tezepelumab, a new biologic medicine, works in real life for adults with chronic sinusitis and nasal polyps. It may help reduce symptoms like congestion and runny nose, and improve quality of life.
This study tests whether dupilumab, a medication given as an injection, helps improve the lining of the nose in people with chronic sinus inflammation and nasal polyps. If you have nasal polyps and are about to start dupilumab, or if you have sinusitis without polyps, you may be eligible to join.
Hear when a new Nasal Polyps trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.