Breathing support for acute chest syndrome in sickle cell disease
Part of Blood & lymphatic, Genetic & congenital, Lungs & breathing clinical trials.
This trial tests whether a breathing machine called CPAP helps people with sickle cell disease who are in the hospital with acute chest syndrome, a serious lung complication. The treatment may improve oxygen levels and help you recover faster.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have sickle cell disease (any type, such as SS, SC, or sickle-beta thalassemia).
- You are 18 years old or older.
- You are in the hospital with acute chest syndrome, which means you have a fever or breathing symptoms and a new shadow on a chest X-ray.
- You need extra oxygen (at least 2 liters per minute) to keep your oxygen level at 95% or above.
- You have not needed this level of oxygen for more than 48 hours already.
- You are not already using oxygen or a breathing machine at home, and you do not have other serious lung diseases like asthma or COPD.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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