CPAP for acute chest syndrome in sickle cell disease
Part of Blood & lymphatic, Genetic & congenital, Lungs & breathing clinical trials.
This trial tests whether CPAP, a breathing machine that helps keep your airways open, can improve oxygen levels in adults with sickle cell disease who are hospitalized for acute chest syndrome. It aims to see if CPAP can help you breathe better and recover faster.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have sickle cell disease (any type: SS, SC, S/beta0, or S/beta+).
- You are 18 years old or older.
- You are in the hospital for acute chest syndrome, which means you have a fever or breathing problems and a new shadow on your lung X-ray.
- You need extra oxygen (at least 2 liters per minute) to keep your oxygen level at 95% or higher.
- You agree to take part and sign a consent form.
- You are not already on home oxygen or a breathing machine, and you do not have other serious lung conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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