Clinical trials
Heart Failure - NYHA II - IV clinical trials
Below are recruiting heart failure - nyha ii - iv clinical trials, each written for real people, not researchers. We’re tracking 52 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06595290Recruiting
Faster medication increase for heart failure with weak pumping
This trial tests a new, faster way to increase heart failure medications during a hospital stay, aiming to get patients on the right doses sooner. It is for people with weak heart pumping (ejection fraction 40% or less) who are currently in the hospital for heart failure and are on low doses of standard medications.
Long Xuyen, An GiangAges 18–75 - NCT05696652Recruiting
Exercise training study for people with heart failure
This study looks for blood and other markers that can explain how people with heart failure respond to exercise training. It may help researchers better tailor exercise or treatment plans for heart failure in the future.
Stanford, CaliforniaAges 18–89 - NCT05960890Recruiting
Study of chronic heart failure after hospital discharge
This study follows adults with chronic or newly diagnosed heart failure to learn how patients do after they leave the hospital, mainly while taking heart medicines by mouth. It may help researchers better understand which patients have different outcomes and needs.
Taizhou, JiangsuAges 18 years+ - NCT06381427Recruiting
Improving care for older heart patients before surgery
This trial studies whether special care planning before non-cardiac surgery can improve outcomes for older adults with signs of heart stress. If you are 65 or older and scheduled for a moderate- to high-risk surgery, you may be able to join.
GiessenAges 65 years+ - NCT06400927Recruiting
AI virtual assistant for managing new heart failure
This trial is testing a smartphone-based virtual assistant that uses artificial intelligence to help manage heart failure after you leave the hospital. It is designed for people who are newly diagnosed with heart failure and have moderate symptoms, to see if the AI assistant can help keep them healthy and out of the hospital.
Stevenage, HertfordshireAges 18 years+ - NCT07218627RecruitingPhase 1
Study of New Drug for Heart Failure
This study tests a new medication called NNC0537-1482 for people with heart failure. It aims to see if the drug is safe and how it affects the body, and may help improve symptoms.
LondonAges 40–75 - NCT07243769Recruiting
Comparing exercise types for heart rehab
This trial compares core, aerobic, and combined exercise in patients doing phase II cardiac rehab. It aims to find which type works best for heart recovery.
TaipeiAges 18 years+ - NCT07513883RecruitingPhase 4
Reducing Heart Failure Medications When Your Heart Recovers
This study tests whether patients whose heart failure has improved can safely reduce some of their medications. If your heart function has recovered significantly and stayed stable, this trial explores whether you can gradually lower doses of heart failure drugs while staying healthy.
GenkAges 18 years+ - NCT07544771Recruiting
HeartLogic monitoring in heart failure patients
This study tests whether a special monitoring system in your heart device (called HeartLogic) can help detect early warning signs of heart failure getting worse. It uses wireless check-ins to track your condition at home and alert your doctor if you need help.
AmiensAges 18 years+ - NCT07397650RecruitingPhase 4
Early finerenone for heart failure in hospital
This trial tests if starting finerenone early helps patients hospitalized with heart failure who have symptoms like shortness of breath or swelling. It aims to see if the drug is safe and effective when given soon after admission.
Handa, Aichi-kenAges 18 years+ - NCT05392764RecruitingPhase 3
SGLT2 medicine for high-risk people after sudden worsening heart failure
This Phase 3 trial tests whether starting an SGLT2 inhibitor early in the hospital can improve outcomes for people at high risk after acute (sudden) heart failure. If you qualify, you would be randomized to receive the study medicine or standard care, started within 12 hours of admission.
Anjo, Aichi-kenAges 20 years+ - NCT05966415RecruitingPhase 2
Endocalyx for heart failure with fluid overload
This Phase 2 study tests Endocalyx to treat people with heart failure who currently show signs of fluid buildup (congestion). If you qualify, you may help researchers see whether this supplement can improve symptoms and heart-failure–related measurements.
Amsterdam, North HollandAges 18–110 - NCT06659393Recruiting
Entresto in children with chronic heart failure
This study is for children with chronic heart failure who are starting Entresto for the first time. It helps doctors learn how well the medicine works and how safe it is for kids.
Ōbu, Aichi-kenAges 1–17 - NCT06049420Recruiting
Lifestyle medicine for rural patients with chronic disease
This trial tests whether exercise therapy can help people with two or more chronic conditions like obesity, diabetes, or heart disease. It's designed for rural patients and requires a referral from your doctor.
Lewisburg, West VirginiaAges 18–64 - NCT06578793Recruiting
Catheter plus vein ablation for atrial fibrillation with heart failure
This trial tests whether adding a vein ablation to standard catheter ablation helps people with persistent atrial fibrillation and heart failure. It aims to find the best treatment to improve heart function and reduce symptoms.
Changsha, HunanAges 18–80 - NCT05609097Recruiting
Exercise program study for older adults with weaker heart pumping
This study tests a new exercise program for people over 65 with heart failure where the heart pumps less efficiently. The goal is to see if tailored exercise is safe and helpful for breathing, energy, and daily function.
Charlottesville, VirginiaAges 65 years+ - NCT05525663Recruiting
Rehab for older adults after heart failure with strong pumping
This trial studies whether a physical rehabilitation program helps older adults recover and function better after a recent hospital stay for heart failure when the heart’s pumping strength is preserved. It may help you regain walking ability and daily independence after your episode.
Winston-Salem, North CarolinaAges 60 years+ - NCT05582044Recruiting
Exercise using leg suction for heart failure with preserved function
This study tests whether a specific lower-body exercise method using negative pressure (leg suction) can improve symptoms and heart-related function in people with heart failure with preserved ejection fraction (HFpEF). You may also be offered screening if you are a healthy person, to compare results.
Kelowna, British ColumbiaAges 40 years+ - NCT06754475Recruiting
Low volume arm HIIT for heart failure patients
This trial tests if short, high-intensity arm exercises can help people with stable heart failure. It looks at safety and improvements in daily function.
Mersin, MersinAges 18 years+ - NCT07321509RecruitingPhase 4
Digoxin after a recent heart failure hospitalization
This trial tests whether digoxin, a heart medication, can help people who were recently hospitalized for heart failure with a weak heart pump. It aims to see if it improves symptoms and daily activity.
Buenos Aires, Buenos Aires F.D.Ages 18–120 - NCT06979362RecruitingPhase 2
Study of CDR132L for heart failure with preserved pumping function
This trial tests if CDR132L can improve heart structure and function in people with a type of heart failure where the heart pumps normally but is stiff and thickened. It may help if you have heart failure with preserved ejection fraction and a thickened heart muscle.
Birmingham, AlabamaAges 40–84 - NCT06979375RecruitingPhase 2
Study of CDR132L for heart failure with reduced pumping ability and thickened heart muscle
This trial tests a new medicine called CDR132L to see if it improves heart structure and function in people with heart failure who have a thickened heart muscle and reduced pumping ability. Participants will be randomly assigned to receive either the study drug or a placebo.
Concord, New South WalesAges 40–84 - NCT07492498Recruiting
Atrial fibrillation care program to prevent heart failure in rural China
This trial tests a new way of caring for older adults with atrial fibrillation (irregular heartbeat) in rural villages to help prevent heart failure. Trained village doctors will use telemedicine (remote healthcare) to manage your condition.
Yancheng, DongtaiAges 65–80 - NCT06271577Recruiting
Smartphone ECG for heart attack detection
This study tests whether a smartphone can take a 12-lead ECG (a heart tracing) quickly when someone arrives at the ER with chest pain, to help doctors spot a heart attack sooner.
Rochester, MinnesotaAges 18 years+
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Common questions
- Are there clinical trials for heart failure - nyha ii - iv?
- Yes. Clin2 currently lists 52 recruiting heart failure - nyha ii - iv studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure - nyha ii - iv trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure - nyha ii - iv trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.