Brain During Surgery: Thinking and Medication Study
Part of Brain & nervous system clinical trials.
This study tests whether giving a drug that affects brain chemistry during brain surgery can improve thinking and attention for people with essential tremor or epilepsy. If you qualify, you might receive the drug or a placebo during your electrode placement surgery to see how it affects your cognition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old and generally healthy aside from essential tremor or epilepsy.
- You are scheduled to have brain surgery that involves placing electrodes deep inside the brain.
- You have not taken blood thinners (such as warfarin or apixaban) within the past week.
- You do not have certain medical conditions, such as moderate to severe liver or kidney problems, untreated narrow-angle glaucoma, bladder blockage, or a history of allergic reaction to Cobenfy or trospium chloride.
- You are not taking certain medications, including specific antidepressants, blood thinners, allergy meds, or bladder control drugs.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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