Tirzepatide for stroke patients after clot removal
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests if tirzepatide, a diabetes drug, can improve recovery in people who had a stroke from a blocked large artery in the brain and then had the clot removed. It may help by reducing inflammation and improving blood sugar control.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old
- You had a stroke caused by a blockage in a major artery in the front of the brain (carotid or middle cerebral artery), confirmed by imaging
- Your stroke severity score (NIHSS) is between 6 and 25 before treatment
- Brain imaging shows a certain amount of salvageable tissue (ASPECTS 6-10)
- You are able to have the clot removal procedure within 24 hours of symptoms starting
- You had no major disability before the stroke (mRS 0-1)
- You have not received clot-dissolving medication (IV thrombolysis) for this stroke
- You do not have active bleeding, severe kidney or liver disease, or low blood counts
- You have not used GLP-1 or GIP receptor agonists before (like Ozempic, Mounjaro)
- You do not have a personal or family history of medullary thyroid cancer or certain genetic conditions
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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