Gels for deep gum pockets in well-controlled diabetes
Part of Hormones & metabolism, Mouth & dental clinical trials.
This study tests two special gels (metformin and zoledronate) applied under the gum after a deep-cleaning procedure, to see which works better for reducing deep gum pockets and regenerating bone, in people with controlled type 2 diabetes and gum disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have type 2 diabetes that is well-controlled, with an HbA1c level below 7.0%.
- You have severe chronic gum disease (periodontitis) with at least one deep pocket (5 mm or deeper) and bone loss.
- You have a specific type of bone loss (at least 3 mm deep) that is confirmed by X-rays and a 3D scan (CBCT).
- You are not a smoker.
- You are not pregnant or breastfeeding.
- You are not taking bisphosphonate medications or other drugs that affect bone metabolism.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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