Metformin or antiseptic gel with deep cleaning for gum disease
Part of Mouth & dental clinical trials.
This study tests whether adding metformin (a diabetes medicine) or chlorhexidine gel (an antiseptic) to standard deep cleaning helps improve gum disease more than deep cleaning alone. It may be an option if you have moderate gum disease and are looking for a non-surgical treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 60 years old.
- You have been diagnosed with stage II, grade B periodontitis (gum disease), with pocket depths of 5 mm or less and attachment loss of 3–4 mm.
- You are generally healthy and do not have other conditions that affect your gums.
- You are not a current smoker or using tobacco products.
- You are not pregnant or breastfeeding.
- You have not taken antibiotics or anti-inflammatory drugs in the last 3 months, and have not had gum treatment in the last 6 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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