Study of heart effects of radiation therapy using PET-CT for stage III lung cancer
Part of Cancer, Heart & circulation, Injuries & trauma, Lungs & breathing clinical trials.
This study looks at whether PET-CT scans can help detect heart damage caused by radiation therapy in patients with stage III lung cancer. If you're getting chemotherapy and radiation together, you may participate to help doctors find ways to reduce heart risks.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have stage III non-small cell lung cancer.
- You must be scheduled to receive chemotherapy and radiation therapy together.
- Your tumor must be near your heart (within 2 cm) or the radiation dose to the heart must be high.
- You must not have had radiation therapy to the chest before.
- You must not have had stereotactic body radiation therapy (SBRT) before.
- You must not have a severe allergy to iodine contrast dye.
- You must not have severe kidney problems (creatinine clearance below 30 mL/min).
- You must be able to hold your breath for at least 5 seconds.
- You must not be taking radioactive iodine therapy.
- You must not have certain heart rhythm problems without a pacemaker.
- You must not have active wheezing from asthma or COPD on the day of the test.
- Your blood pressure must be adequate (systolic at least 90 mm Hg) on the day of the test.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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