Magnesium sulfate to reduce brain inflammation after moderate head injury
Treatments studied
Part of Brain & nervous system, Injuries & trauma clinical trials.
This study tests whether giving magnesium sulfate (a common mineral supplement) soon after a moderate head injury can reduce brain swelling and inflammation. It aims to see if this treatment helps protect the brain and improve recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 60 years old.
- You had a closed head injury (no open wound or object going into the brain) within the last 8 hours.
- Your brain injury is moderate, meaning you are confused but can still follow simple commands.
- A CT scan of your head shows changes typical of head trauma, like swelling or bleeding.
- You do not have a spinal cord injury, other serious body injuries, or need surgery during the study.
- You are not pregnant or breastfeeding, and you have no known allergy to magnesium sulfate.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether giving magnesium sulfate early after a traumatic brain injury can prevent blood vessels in the brain from tightening (a condition called vasospasm), which can reduce blood flow and cause further damage. If you've had a head injury with bleeding around the brain, this treatment might help improve your recovery.
This trial tests whether a magnesium infusion can better control pain in adults who have serious injuries and need intensive care. It compares magnesium as part of pain treatment to standard pain care to see if pain improves and stays controlled.
This trial tests whether giving magnesium directly into the artery during mechanical thrombectomy (a procedure to remove a blood clot from the brain) improves recovery after a severe ischemic stroke. Magnesium may help protect brain cells from further damage after the clot is removed.
This study tests whether memantine, a medicine usually used for memory problems, can help people recover from mild to moderate traumatic brain injury. You would receive memantine along with your standard care, starting within 24 hours of the injury.
This trial tests whether giving steroids can reduce brain swelling after a mild or moderate head injury. If you or a loved one had a brain injury within the last few days and the CT scan shows bruising, this study may offer extra treatment to help control swelling.
This trial tests whether a medicine called dexamethasone, which reduces swelling, can improve recovery after a mild or moderate brain injury. It might help by decreasing pressure inside the skull.
Hear when a new Traumatic Brain Injuries trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.