Clin2
NCT07771595Possibly a fitNot yet recruiting

Does atomoxetine boost motivation in healthy adults?

Apathy

Treatments studied

Part of Brain & nervous system clinical trials.

This study tests whether atomoxetine, a medication that affects brain chemicals, can boost motivation in healthy adults. If you join, you'll be helping researchers understand the drug's effects and whether it might help with conditions that affect motivation.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
40 people
Ages
18 years to 45 years
Study type
Interventional

Who can take part

  • You are between 18 and 45 years old.
  • You are in good physical health.
  • You can give informed consent and understand English well enough to complete study tasks.
  • You do not have a serious mental health condition, heart problems, high blood pressure, or other significant medical conditions.
  • You are not taking certain medications (e.g., for the brain, heart, or blood pressure).
  • For women: you are not pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06696482Not yet recruiting· Phase 1/Phase 2
Effort and antidepressant study test

This trial tests how a common antidepressant (escitalopram) affects motivation and effort in healthy adults. It uses brain scans and tasks to understand the medication's effects.

NCT05877885Recruiting
Digital treatment for low motivation in older adults with depression

This study tests a digital therapy to improve apathy (feeling unmotivated or “checked out”) in people age 60+ who have depression. It also uses brain imaging (MRI) and questionnaires to see whether the treatment helps brain function linked to motivation.

Orlando, Florida
NCT07279740Recruiting· Phase 2
Brain stimulation plus medication for apathy in dementia

This study tests if combining a type of brain stimulation (repetitive TMS) with a medication (methylphenidate, commonly used for ADHD) can improve apathy in people with dementia. If you have Alzheimer's or mixed dementia and struggle with low motivation, this trial may help you.

Toronto, Ontario
NCT07724132Recruiting· Phase 3
Treatments for sustained response in Alzheimer's disease

This study tests whether a treatment (atomoxetine or metformin) can help people with Alzheimer's disease maintain an improved state for at least 18 months. It may help you or a loved one stabilize symptoms and slow disease progression.

Cambridge
NCT05561205Recruiting
Brain stimulation to treat persistent apathy

This trial tests a noninvasive brain stimulation treatment (called rTMS) to help people who have had ongoing apathy (lack of motivation/interest) for at least a month. You might benefit if your apathy is persistent, your other symptoms are stable, and you meet the safety and medication rules.

Toronto, Ontario
NCT07239791Recruiting
Does a low-dose medication affect how we learn?

This study tests whether a very low dose of a medication called atomoxetine, which affects a brain chemical called noradrenaline, can help with how people learn. It is for right-handed adults who are generally healthy and not taking other medications.

Paris

Hear when a new Apathy trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.