Clin2
NCT07781085Worth exploringRecruiting

Radiation therapy after surgery for early glottic cancer

Early Stage Glottic Squamous Cell Carcinoma Involving the Anterior Commissure

Part of Cancer, Ear, nose & throat clinical trials.

This study looks at whether adding radiation therapy after surgery improves outcomes for people with early-stage glottic cancer that involves the anterior commissure (the front part of the vocal cords). If you join, you may receive radiation therapy or not, and the researchers will compare the results.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
38 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have a confirmed diagnosis of glottic squamous cell carcinoma (a type of throat cancer).
  • Your cancer is stage T1 or T2 and has not spread to lymph nodes or distant sites (N0M0).
  • You have undergone surgery to remove the cancer within the last 4 to 8 weeks, and the margins were negative (no cancer at the edges).
  • You have not received prior radiation therapy, chemotherapy, or other anti-cancer treatments.
  • You have an ECOG performance status of 0 or 1 (meaning you are fully active or restricted only in physically strenuous activity).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07781098Recruiting
Radiation therapy for early-stage voice box cancer with poor differentiation

This trial studies whether adding radiation therapy after surgery can help people with early-stage voice box cancer that has poor differentiation (cells look very abnormal). It aims to improve outcomes for this specific type of cancer.

Hangzhou, Zhejiang
NCT06306846Recruiting· Phase 2
Radiation and immunotherapy before surgery for head and neck cancer

This study tests giving a short course of targeted radiation (SBRT) along with immunotherapy and a targeted drug before surgery for advanced head and neck cancer. The goal is to see if this combination can shrink the tumor and improve outcomes.

Hangzhou, Zhejiang
NCT06485778Recruiting· Phase 2
Radiation after surgery for early-stage oral tongue cancer

This trial tests whether giving radiation after surgery can lower the risk of the cancer coming back for people with oral tongue cancer that has specific high-risk features but not advanced spread. It aims to find the best treatment plan for patients with certain tumor characteristics.

Basking Ridge, New Jersey
NCT04224389Recruiting
Radiation plus throat surgery for early tonsil or tongue-base cancer

This study compares ways of treating early squamous cell cancer in the tonsil or the tongue base, using either radiation therapy, transoral (through-the-mouth) surgery, or both. It aims to see which approach works best while keeping cancer under control.

Villejuif, Val De Marne
NCT07402525Recruiting
Radiation after surgery for early-stage tongue cancer with risk factors

This trial tests whether adding radiation therapy after surgery helps prevent the return of early-stage tongue cancer in patients who have certain risk factors, such as nerve invasion or poorly differentiated cells. It is for people whose cancer was limited to the front two-thirds of the tongue and was completely removed.

Bengbu, Anhui
NCT07197060Not yet recruiting
Short-course radiation for early vocal cord cancer

This trial tests a shorter course of radiation therapy for early-stage vocal cord cancer. The aim is to see if giving slightly higher doses per session (3.5 Gy) is safe and effective.

Hear when a new Early Stage Glottic Squamous Cell Carcinoma Involving the Anterior Commissure trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.