New heart valve for severe aortic stenosis
Part of Heart & circulation clinical trials.
This trial tests a new replacement heart valve for people with severe aortic stenosis (narrowing of the aortic valve). The valve is placed without open-heart surgery. It aims to be safer and work better for patients who are at intermediate or higher risk for surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe aortic stenosis as defined by standard guidelines.
- Your surgical risk is intermediate or higher, which is often measured by a score called STS of 4% or more.
- Your doctor has said you need a transcatheter aortic valve replacement.
- You are willing and able to give written consent to join the study.
- You are not already excluded for reasons like recent stroke, bleeding risk, or very low kidney function.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new type of aortic valve replacement that can be inserted without open-heart surgery. It's designed for people with severe aortic stenosis who are not suitable for a standard operation.
This trial studies a new “valve-in-valve” procedure to treat a failing aortic bioprosthetic valve. It may help people improve blood flow through the heart valve and reduce valve-related problems.
This study tests whether a less invasive valve replacement (TAVI) can be done safely in hospitals that don't have a full heart surgery team on site. If you have severe aortic stenosis and are 70 or older, this trial might offer a new option with a shorter recovery than open-heart surgery.
This study tests a new replacement valve for the aortic heart valve, delivered through a catheter (a thin tube) — a procedure called TAVR. It is for people who have severe aortic stenosis and are not good candidates for open-heart surgery.
This trial is testing a new, less invasive way to replace a narrowed aortic valve using a special device. The goal is to help improve blood flow and reduce symptoms like chest pain and shortness of breath.
This trial tests a new version of a heart valve (SAPIEN X4) placed without open-heart surgery. It's for people with severe aortic stenosis who have symptoms like shortness of breath or chest pain.
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