Clin2
NCT07815119Possibly a fitRecruiting

Comparing two heart imaging methods before a stroke-prevention procedure

Nonvalvular Atrial Fibrillation

Part of Heart & circulation clinical trials.

This study compares two imaging methods (TEE and CCTA) used before a procedure to close a small pouch in the heart, which helps prevent strokes in people with atrial fibrillation. Participants will be randomly assigned to one method, and both groups will be checked after 3 months to see which imaging works better.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
590 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You must have a type of irregular heartbeat called atrial fibrillation (not caused by a heart valve problem).
  • Your doctor must have already decided that closing a small pouch in your heart (the left atrial appendage) is right for you to reduce stroke risk.
  • You must be able to have two imaging tests before the procedure: one using sound waves (TEE) and one using X-rays (CCTA).
  • You must be willing to return for check-up tests 3 months after the procedure.
  • You must not have severe kidney disease, a serious allergy to contrast dye, or severe esophageal problems.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06969118Not yet recruiting
Comparing two procedures to close the left atrial appendage in atrial fibrillation

This study compares two ways of closing a small pouch in the heart (the left atrial appendage) to help prevent strokes in people with atrial fibrillation (an irregular heartbeat). One method is less invasive, and the study aims to see if it is as safe and effective as the standard approach.

Shanghai, Shanghai Municipality
NCT06348394Recruiting
Comparing heart imaging methods for a procedure to prevent stroke

This trial is testing two ways to guide a procedure that closes a small pouch in the heart to lower the risk of stroke in people with atrial fibrillation. The goal is to see if one method is as good or better than the other.

Plano, Texas
NCT04800913Recruiting
Imaging tests during left atrial appendage closure

This study looks at how different imaging tests can help guide a procedure that closes off the left atrial appendage to reduce stroke risk. It may help doctors choose the safest approach during the procedure.

Budapest
NCT06061757Recruiting
Combining 4D-ICE and TEE imaging for heart closure

This trial tests a new imaging method (4D-ICE) used alongside a standard ultrasound (TEE) during a heart procedure to close the left atrial appendage, a small pouch in the heart where clots can form in people with atrial fibrillation. The goal is to see if the new method makes the procedure safer and more precise.

Overland Park, Kansas
NCT05420701Not yet recruiting
Comparing two ways to close the heart's left atrial appendage

This study compares two ways to close off a small heart pouch (the left atrial appendage) to reduce stroke risk in people with atrial fibrillation. The goal is to see which method—surgery or a less invasive tube-based approach—works better and is safer.

NCT04559243Recruiting
Left atrial appendage closure to prevent stroke in AF

This study tests whether closing a heart pocket called the left atrial appendage can lower future stroke or other clot-related events in people with atrial fibrillation. It’s mainly for people who have had a prior clot-related event or are at higher risk but may not be good candidates for long-term blood thinners.

Jinan, Shandong

Hear when a new Nonvalvular Atrial Fibrillation trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.