Clinical trials
Non Valvular Atrial Fibrillation clinical trials
Below are recruiting non valvular atrial fibrillation clinical trials, each written for real people, not researchers. We’re tracking 81 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04559243Recruiting
Left atrial appendage closure to prevent stroke in AF
This study tests whether closing a heart pocket called the left atrial appendage can lower future stroke or other clot-related events in people with atrial fibrillation. It’s mainly for people who have had a prior clot-related event or are at higher risk but may not be good candidates for long-term blood thinners.
Jinan, ShandongAges 18 years+ - NCT04432220RecruitingPhase 4
Taking blood thinners one year after atrial fibrillation ablation
This study looks at whether people who have stayed in normal rhythm one year after atrial fibrillation ablation should continue blood thinning treatment. It may help guide safer, more personalized choices about long-term blood thinners after a successful procedure.
SeoulAges 19–80 - NCT03642509Recruiting
Compare a heart procedure to blood-thinner pills for stroke prevention
This trial studies whether closing off part of the heart (the left atrial appendage) can prevent stroke as well as long-term newer blood-thinner pills. It may help people with atrial fibrillation who recently had a stroke or a warning stroke (TIA).
Aarhus, Central JutlandAges 18 years+ - NCT06187311RecruitingPhase 4
Rivaroxaban for atrial fibrillation patients
This trial tests two doses of rivaroxaban (15mg and 20mg) to see how well they prevent strokes in people with non-valvular atrial fibrillation, a type of irregular heartbeat not caused by a heart valve problem. It may be an option if you need blood thinners to lower your stroke risk.
SeoulAges 19–99 - NCT04715425Recruiting
Surgery vs catheter procedure for persistent atrial fibrillation
This trial compares two ways to treat persistent atrial fibrillation: a minimally invasive surgery approach versus a catheter ablation. It may help people find the most effective option to reduce ongoing abnormal heart rhythm and avoid repeat procedures.
AmsterdamAges 18–80 - NCT06363604Recruiting
Alcohol injection with ablation for persistent atrial fibrillation
This trial is testing a new approach to treat persistent atrial fibrillation (a type of irregular heartbeat) by combining standard catheter ablation with a special injection of alcohol (ethanol) into certain heart veins. It may help people whose symptoms haven't improved with medication.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT05204212Recruiting
Heart procedure to close an atrial clot risk pouch in kidney failure
This trial tests a heart procedure that closes a part of the heart called the left atrial appendage to help prevent stroke in people with an irregular heartbeat (atrial fibrillation) and very advanced kidney disease. It’s mainly for patients who can take the needed blood-thinner medicines and who do not already have a clot in that pouch.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT03355456Recruiting
Catheter ablation for atrial fibrillation with low-voltage mapping
This trial studies a catheter procedure that targets areas in the heart that show low electrical voltage to treat atrial fibrillation (an irregular heartbeat). You may be eligible if you have non-paroxysmal atrial fibrillation, have tried heart rhythm medicines, and your scan shows low-voltage areas in the left atrium.
Cleveland, OhioAges 18–85 - NCT07816029Recruiting
Closing a heart pouch to prevent stroke in atrial fibrillation
This study tests a device and procedure to close off a small pouch in the heart (left atrial appendage) where blood clots can form in people with atrial fibrillation. The goal is to reduce the risk of stroke, possibly lowering the need for long-term blood thinners.
PragueAges 18 years+ - NCT05598632Recruiting
People with atrial fibrillation registry to study stroke risk
This registry study follows people with atrial fibrillation to learn which risk factors are linked to stroke or blood clots traveling through the body. Your information helps improve how doctors predict risk and choose prevention strategies.
Beijing, Beijing MunicipalityAges 18–120 - NCT07654634Enrolling by invitation
Precision blood thinning therapy study
This trial tests personalized blood thinner treatment for people who need long-term anticoagulation for conditions like atrial fibrillation or blood clots. The goal is to find the safest and most effective dose for each patient.
Changsha, HunanAges 8 years+ - NCT07575269Recruiting
New ablation treatment for irregular heartbeat
This trial tests a new tool called FARAFLEX that uses pulsed electrical energy to treat atrial fibrillation (an irregular heart rhythm). The goal is to see if this method can safely stop AF symptoms in people whose medications haven't worked.
Jonesboro, ArkansasAges 18 years+ - NCT07523750Recruiting
Pulsed field ablation for persistent atrial fibrillation
This study tests two types of pulsed field ablation catheters to treat persistent atrial fibrillation, a heart rhythm problem lasting more than 7 days but less than a year. The goal is to see if these catheters can safely and effectively restore a normal heart rhythm.
Jonesboro, ArkansasAges 18–80 - NCT07441382Recruiting
Comparing treatments for frail older adults with atrial fibrillation
This study tests whether combining a heart procedure (catheter ablation) with a device to close the left atrial appendage (LAAO) is safer or better than blood thinners alone for frail patients 75 years or older with atrial fibrillation and high stroke risk. It aims to find a treatment that reduces stroke while lowering bleeding risks.
Guangzhou, GuangdongAges 75 years+ - NCT07424690Recruiting
Comparing ablation with medication care for older adults with atrial fibrillation
This study compares two approaches for older adults with atrial fibrillation: a procedure called catheter ablation (which uses heat or cold to fix the heart's rhythm) versus conservative care (medications and lifestyle changes). The goal is to see which approach is better for improving quality of life and reducing symptoms in people aged 78 and above.
LinköpingAges 78 years+ - NCT07385599Recruiting
Study of a new heart device for atrial fibrillation patients
This trial tests a new device called LAmbre™ II that closes off a part of the heart called the left atrial appendage to help prevent strokes in people with atrial fibrillation who cannot take blood thinners.
ShatinAges 18 years+ - NCT07324772Recruiting
Exercise program to improve symptoms in atrial fibrillation and heart failure
This study tests if starting a supervised exercise program can help older adults with both atrial fibrillation and a type of heart failure called HFpEF feel better and have a better quality of life. You'll be asked to join exercise sessions and have regular check-ins to see how you're doing.
Chicago, IllinoisAges 60–99 - NCT07298473Recruiting
Redo ablation for recurrent atrial fibrillation with Sphere-9 catheter
This trial tests a new catheter and system for people who have had one previous ablation for atrial fibrillation but still have symptoms. It aims to see if a repeat procedure can safely and effectively treat recurrent episodes.
Birmingham, AlabamaAges 18 years+ - NCT07278869Recruiting
Study of Append system for atrial fibrillation patients
This trial tests a new device, the Append System, to close off the left atrial appendage (a small pouch in the heart) in people with atrial fibrillation. The goal is to reduce stroke risk without needing long-term blood thinners.
Jonesboro, ArkansasAges 18 years+ - NCT07267949RecruitingPhase 2
Study of AP31969 for atrial fibrillation rhythm control
This study tests a new medication, AP31969, to control heart rhythm in people with atrial fibrillation. It compares the drug to a placebo to see if it can reduce how often AF episodes happen over time.
Plovdiv, PDAges 18 years+ - NCT05900414Recruiting
Help choosing blood thinners to prevent stroke in AF
This trial tests a web-based decision aid that helps people with atrial fibrillation (AF) decide about stroke-prevention treatment, such as blood thinners. It may help you feel more confident and make safer choices by showing options at the right time after diagnosis.
Calgary, AlbertaAges 18 years+ - NCT06949319Recruiting
Stroke Risk and Blood Clots in New Atrial Fibrillation
This study looks at stroke risk and blood clotting in people who have just been diagnosed with atrial fibrillation (AFib) that is not caused by a heart valve problem, and who have not yet taken blood thinners. It aims to better understand how blood clots form in this condition.
Esbjerg, Region SyddanmarkAges 18 years+ - NCT07171463Recruiting
New ablation for paroxysmal atrial fibrillation
This trial tests a new treatment that uses two types of energy (pulsed field and radiofrequency) to fix the heart's electrical signals in people with paroxysmal atrial fibrillation (AFib that comes and goes). It aims to be more effective and safer than standard ablation alone.
Rzeszów, Podkarpackie VoivodeshipAges 18 years+ - NCT07116525Recruiting
Study of heart mapping for abnormal rhythms
This trial tests a special catheter to map abnormal heart rhythms like ventricular tachycardia or atrial fibrillation. It may help patients who need a procedure to find and treat the source of these fast or irregular heartbeats.
BrugesAges 18 years+
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Common questions
- Are there clinical trials for non valvular atrial fibrillation?
- Yes. Clin2 currently lists 81 recruiting non valvular atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a non valvular atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a non valvular atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.