Closing the heart pouch versus medication for atrial fibrillation
Part of Heart & circulation clinical trials.
This study compares a procedure to close a small pouch in the heart (which is a common source of blood clots causing stroke) to using medications alone in people with atrial fibrillation who cannot safely take blood thinners. The goal is to see if this procedure can reduce stroke risk without the bleeding risks of long-term blood thinners.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older and have atrial fibrillation.
- You must have a moderate to high risk of stroke and either be at high risk of bleeding or be unable to take blood thinners.
- You must not be too frail or have significant lung disease.
- You must not have had open-heart surgery or previous chest radiation.
- You must not be taking blood thinners for other conditions, and you must be able to understand study information in the local language.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests if adding a special energy treatment (pulsed field ablation) to a standard heart pouch closure is safe and works better for people with persistent atrial fibrillation who have few symptoms but a high risk of stroke.
This trial tests if closing the left atrial appendage with a special stitch during planned heart surgery can help prevent strokes in people with atrial fibrillation. If you already need heart surgery, this extra step may reduce your future stroke risk.
This trial tests whether it is safe for patients with atrial fibrillation to stop taking blood thinners after they have had heart surgery, including closure of the left atrial appendage. The goal is to see if these patients can avoid long-term medication without increasing the risk of stroke.
This study tests a device and procedure to close off a small pouch in the heart (left atrial appendage) where blood clots can form in people with atrial fibrillation. The goal is to reduce the risk of stroke, possibly lowering the need for long-term blood thinners.
This study tests whether closing a heart pouch called the left atrial appendage can prevent future strokes in people with atrial fibrillation who had an ischemic stroke even while taking blood thinners. It may help reduce stroke risk by blocking a common place where clotting can start.
This study compares two ways of closing a small pouch in the heart (the left atrial appendage) to help prevent strokes in people with atrial fibrillation (an irregular heartbeat). One method is less invasive, and the study aims to see if it is as safe and effective as the standard approach.
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