Keyhole procedure to close heart pocket vs. medication for atrial fibrillation
Part of Heart & circulation clinical trials.
This trial compares a minimally invasive keyhole surgery to close the left atrial appendage (a small pocket in the heart where clots can form) with continuing blood-thinning medication. It aims to lower stroke risk for people with atrial fibrillation who have a high risk of bleeding or cannot take blood thinners.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older
- You have atrial fibrillation and a high stroke risk (CHA2DS2-VA score of 2 or more)
- You either have a high bleeding risk or cannot take blood thinners for medical reasons
- You do not have severe frailty, advanced lung disease, or prior heart surgery
- You are not currently scheduled for another heart procedure or ablation
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if closing the left atrial appendage with a special stitch during planned heart surgery can help prevent strokes in people with atrial fibrillation. If you already need heart surgery, this extra step may reduce your future stroke risk.
This trial tests whether it is safe for patients with atrial fibrillation to stop taking blood thinners after they have had heart surgery, including closure of the left atrial appendage. The goal is to see if these patients can avoid long-term medication without increasing the risk of stroke.
This trial studies whether closing off part of the heart (the left atrial appendage) can prevent stroke as well as long-term newer blood-thinner pills. It may help people with atrial fibrillation who recently had a stroke or a warning stroke (TIA).
This study looks at a part of the heart called the left atrial appendage during open-heart surgery. It aims to learn more about heart rhythm problems and blood clots, which may help improve future treatments.
This study tests whether closing a heart pocket called the left atrial appendage can lower future stroke or other clot-related events in people with atrial fibrillation. It’s mainly for people who have had a prior clot-related event or are at higher risk but may not be good candidates for long-term blood thinners.
This study is testing a minimally invasive procedure to close off a part of the heart (the left atrial appendage) in people with kidney failure on dialysis who also have atrial fibrillation. The goal is to reduce the risk of stroke without needing long-term blood thinners.
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