Clin2
NCT07817082Possibly a fitRecruiting

A new drug for her2 ultra-low advanced breast cancer

Advanced Breast Cancer With Ultra-Low HER2 Expression

Treatments studied

Part of Cancer, Women’s health & pregnancy clinical trials.

This study tests a new targeted drug (SHR-A1811) for breast cancer that has very low HER2 levels. The drug is designed to attack cancer cells with this specific marker, and the study aims to see if it can help slow the cancer's growth.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
30 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are a woman aged 18 to 75.
  • You have advanced or metastatic breast cancer that has grown despite previous treatment.
  • Your tumor was tested and shows very low levels of HER2 (below the usual 'positive' cutoff).
  • You have not had more than 2 prior lines of treatment for advanced disease (for hormone-blocking therapies, if applicable).
  • You have at least one tumor that can be measured on scans.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07560475Not yet recruiting· Phase 2
Different ways to give a new drug for HER2-positive breast cancer

This study tests a new drug called SHR-A1811, given by different methods, to find the best way to treat advanced HER2-positive breast cancer. It may help if you have had few treatments so far and have not had this type of drug before.

Tianjin
NCT06704828Not yet recruiting· Phase 2
Study of a new drug for advanced solid tumors with her2

This trial tests an investigational drug (SHR-4602) alone or with other treatments for advanced solid tumors that have HER2. The goal is to see if it can shrink or control the cancer.

Beijing, Beijing Municipality
NCT07111832Recruiting· Phase 3
Study of SHR-A1811 for triple-negative breast cancer

This study tests a new drug called SHR-A1811 for people with triple-negative breast cancer that has spread or come back. It looks at whether the drug can help shrink tumors or slow the cancer's growth.

Beijing, Beijing Municipality
NCT07047443Not yet recruiting· Phase 2
New drug plus carboplatin for advanced breast cancer with her2

This study tests a new drug (SHR-1811) combined with a standard chemotherapy drug (carboplatin) for advanced breast cancer that shows HER2, even at low levels. It may offer a new option for people whose cancer has stopped responding to previous treatments.

Hefei, Anhui
NCT07129187Not yet recruiting· Phase 2
Study of SHR-A1811 for HER2-positive breast cancer after poor response to initial therapy

This trial tests a new drug called SHR-A1811 for women with HER2-positive breast cancer that did not shrink enough after the first four rounds of chemotherapy before surgery. The goal is to see if this drug can improve outcomes for patients who need a different treatment approach.

NCT07787338Not yet recruiting· Phase 2
SHR-A1811 alone or with standard therapy before surgery for HER2-positive breast cancer

This trial tests a new drug, SHR-A1811, given alone or followed by a standard treatment, before surgery for early-stage HER2-positive breast cancer. The goal is to see if it can shrink tumors and improve outcomes.

Hangzhou, Zhejiang

Hear when a new Advanced Breast Cancer With Ultra-Low HER2 Expression trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.