Clinical trials
Pediatric Critical Illness clinical trials
Below are recruiting pediatric critical illness clinical trials, each written for real people, not researchers. We’re tracking 24 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06223828RecruitingPhase 2/Phase 3
Azithromycin for Children with Severe Asthma in the ICU
This trial tests whether adding the antibiotic azithromycin to standard asthma treatments helps children with severe asthma in the pediatric intensive care unit (PICU) recover faster. It is for children ages 3 to 17 who are already receiving strong asthma medicines and steroids.
St. Petersburg, FloridaAges 3–17 - NCT05867472RecruitingPhase 3
Sedation plan for critically ill children on breathing machines
This Phase 3 trial tests a sedation approach using inhaled (“volatile”) anesthesia gases for children who need a ventilator. It aims to improve comfort and brain-related outcomes while they stay on the breathing machine for at least a day.
Hamilton, OntarioAges 1 month–18 years - NCT06220825Recruiting
Breathing support practices in critically ill children
This trial looks at how doctors manage breathing support for children in the intensive care unit. It may help improve care for kids who need help breathing.
GroningenAges Up to 18 years - NCT06721923Recruiting
Comparing protein delivery methods in critically ill children
This study looks at whether giving protein continuously or all at once is better for children in intensive care. The goal is to find the most effective way to support recovery.
Vancouver, British ColumbiaAges 1–11 - NCT02539407Recruiting
Study drug levels in critically ill children
This trial measures how anti-infective medicines move through a child’s body while they are in the hospital or during follow-up. The goal is to better understand dosing and drug exposure in critically ill children.
ParisAges 1 day–18 years - NCT07384585Recruiting
Light therapy study for children in the ICU
This study tests whether light therapy can help children in the pediatric intensive care unit (ICU) feel better and recover. A parent or guardian must be at the bedside and speak English.
Columbus, OhioAges 4–17 - NCT04201704Recruiting
Less IV fluids for children after trauma
This trial studies whether giving children less fluid through a vein after serious injury helps them recover safely. Children are enrolled soon after arrival to the ICU so the team can compare outcomes between different fluid amounts.
Buffalo, New YorkAges 6 months–15 years - NCT07128446Recruiting
Goal setting with COPM in the PICU
This trial is testing a new way to set goals for children in the pediatric intensive care unit. Researchers want to see if a tool called COPM helps caregivers and therapists work together to choose the most important rehab goals.
Seoul, Gangnam-guAges 1–18 - NCT07478380Recruiting
Skin oxygen monitoring in pediatric ICU
This study checks if a skin sensor can accurately measure oxygen levels in the blood of children in the intensive care unit, compared to standard blood tests. It may help reduce the need for frequent needle sticks.
Istanbul, KadıkoyAges 1 month–18 years - NCT05055830Recruiting
Study blood drug levels in critically ill children
This trial measures how the study medicines move through the body and how they affect the child in the Pediatric Cardiac Intensive Care Unit. It may help doctors choose safer and better dosing for critically ill children.
Durham, North CarolinaAges birth–20 years - NCT05246098Recruiting
Rehabilitation program study for young and adult ICU COVID/respiratory survivors
This study looks at whether a rehabilitation approach improves recovery outcomes for people who survived COVID-19 or a serious breathing infection and needed ICU/PICU care. It may help those still dealing with physical or functional problems after their critical illness.
Calgary, AlbertaAges Any age - NCT06481644Recruiting
Study of kids in Asian pediatric ICUs
This study looks at children admitted to pediatric intensive care units (ICUs) in Asia to understand their health patterns and outcomes. It may help improve care for future patients.
SingaporeAges Any age - NCT07027813Recruiting
Ambulance video care for children
This trial tests whether using a tablet computer and video connection in an ambulance helps doctors and emergency workers care for children during the ride to the hospital. It aims to see if this approach is practical and improves treatment.
Karachi, SindhAges 1 minute–14 years - NCT06117345Enrolling by invitation
PICU Journal for Parents and Caregivers
This study tests a journal to help parents and caregivers stay involved while their child is in the pediatric intensive care unit (PICU). It aims to see if the journal improves communication and engagement.
Nashville, TennesseeAges 18 years+ - NCT07307027Recruiting
Feeding plan for children in intensive care
This study tests a step-by-step feeding plan (enteral nutrition) for children in the pediatric ICU to see if it improves their recovery. It might help if your child is critically ill and can receive nutrition through a tube.
Cairo, AbbasiaAges 1 month–16 years - NCT04534296Recruiting
Early mobilization for breathing muscles in critically ill children
This study looks at whether starting movement early in the first day of breathing support can help keep the diaphragm (a key breathing muscle) working better in critically ill children. The researchers will check diaphragm thickness using ultrasound and compare it to usual care.
ShanghaiAges 6 months–12 years - NCT07522580Recruiting
Heart Fluid Response Monitoring in Critically Ill Children
This study tests a simple, non-invasive device that measures how well a child's heart responds when doctors give extra fluids during intensive care. It helps doctors decide if more fluids will actually help the child feel better.
Le Plessis-Robinson, FranceAges birth–8 years - NCT04166877RecruitingPhase 4
Magnesium drip to reduce pain in ICU trauma patients
This trial tests whether a magnesium infusion can better control pain in adults who have serious injuries and need intensive care. It compares magnesium as part of pain treatment to standard pain care to see if pain improves and stays controlled.
Sacramento, CaliforniaAges 18 years+ - NCT04801589RecruitingPhase 3
Guided sedation for children on a breathing machine
This study tests a “goal-directed” approach to sedation (giving the right amount based on target goals) for children who need a breathing machine in the pediatric ICU. The goal is to reduce brain and recovery side effects while keeping children comfortable and safe.
Nashville, TennesseeAges 10 months–11 years - NCT06034990Recruiting
ICU fluid use survey for Southeast Asian doctors
This survey asks doctors in Southeast Asian ICUs about how they use fluids (like IV fluids) for their patients. It's a simple questionnaire to understand current practices and help improve care.
Bangkok, BangkokAges 18–60 - NCT06323226Recruiting
Sepsis long-term outcomes in critically ill children
This study looks at how sepsis (a severe infection that can affect the whole body) affects children after they leave the intensive care unit. It compares children who had sepsis to those with other critical illnesses to understand long-term health.
Chengdu, SichuanAges birth–16 years - NCT03419260Recruiting
Continuous EEG monitoring in critically ill children
This study looks at whether continuous brain-wave monitoring can guide seizure care in sick children in the pediatric intensive care unit. It also studies how this approach may affect children’s thinking and behavior later.
Philadelphia, PennsylvaniaAges 1 month–18 years - NCT04987840Enrolling by invitation
Hospital program to reduce unnecessary lung culture tests in kids
This trial studies a hospital quality-improvement program that aims to use fewer “respiratory culture” tests in pediatric intensive care units (PICUs). It may help reduce unnecessary testing while maintaining good care for critically ill children.
Baltimore, MarylandAges Any age - NCT07070258Recruiting
Pediatric ICU Transport Registry
This study records information on critically ill children who are moved between hospitals by a special critical care team. It looks at how these transports happen to improve care for future kids.
DresdenAges 4 weeks–17 years
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Common questions
- Are there clinical trials for pediatric critical illness?
- Yes. Clin2 currently lists 24 recruiting pediatric critical illness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pediatric critical illness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pediatric critical illness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.