Clin2
NCT07822984Possibly a fitNot yet recruiting

Adding focused radiation to EGFR pill and chemo for lung cancer

EGFR-mutant Non-small Cell Lung CancerSBRTNSCLC (Advanced Non-small Cell Lung Cancer)

Part of Cancer, Lungs & breathing clinical trials.

This trial tests whether adding focused radiation therapy to the spots of cancer that remain after your first treatment (an EGFR pill plus chemo) can help control advanced lung cancer better. It is for people whose cancer has an EGFR mutation and who have only a few residual spots, with the goal of delaying progression and improving outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
374 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You must have stage IV non-small cell lung cancer that has spread.
  • Your cancer must have a specific EGFR mutation (either exon 19 deletion or L858R).
  • Your first treatment was a third-generation EGFR pill plus chemotherapy, and you completed 4 cycles without the cancer getting worse.
  • After those 4 cycles, you have only a few remaining spots of cancer that can be treated with focused radiation.
  • You are between 18 and 75 years old and generally in good health (able to do daily activities with some limitations).
  • You have no other active cancers, and you are not pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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