Melatonin or lidocaine to prevent confusion after hip replacement
Part of Brain & nervous system, Mental health clinical trials.
This trial tests if giving either oral melatonin or lidocaine during surgery can reduce the chance of confusion (delirium) in older adults after total hip replacement. It compares these two approaches to standard care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 66 years or older and scheduled for a first-time hip replacement on one side.
- Your BMI is between 18 and 30.
- You are generally healthy or have mild to moderate medical conditions (ASA status I-III).
- You do not have a history of mental illness or score less than 8 on a memory test before surgery.
- You are not taking certain medications for mental health, seizures, Parkinson's, or depression.
- No allergies to melatonin or lidocaine, and no serious heart, brain, liver, or kidney problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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