Semaglutide before weight-loss surgery for very high BMI
Part of Hormones & metabolism clinical trials.
This trial tests whether taking a weekly injection called semaglutide (a type of medicine used for weight loss) for about 16 weeks before weight-loss surgery can help people with a very high BMI prepare for surgery. It may reduce liver fat and make surgery safer, which could lead to better outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your body mass index (BMI) is 60 or higher at your first surgery consultation.
- Your surgical team has already accepted you for a first weight-loss surgery (either sleeve gastrectomy or gastric bypass).
- You are able to give yourself injections and you agree to participate.
- You have not had any previous weight-loss surgery or major surgery on your belly.
- You have not used any GLP-1 weight-loss medicine (like Ozempic or Wegovy) in the past 6 months.
- You do not have type 1 diabetes, a history of pancreatitis, or serious stomach or gut problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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