Antibiotics for preventing leptospirosis infection
Treatments studied
Part of Infections clinical trials.
This study tests whether taking an antibiotic, doxycycline, can help prevent leptospirosis, a bacterial infection you can get from water or soil that may be contaminated by animal urine. If you've been exposed to risky environments, this trial aims to see if the medicine can stop you from getting sick.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have recently been in contact with water or soil that could be contaminated, such as wet ground at work or areas with animals.
- You do not have a fever (temperature below 38°C).
- You have not been diagnosed with leptospirosis in the last 3 months.
- You are not pregnant or breastfeeding.
- You are not allergic to doxycycline.
- You do not have severe liver problems (like cirrhosis Child-Pugh C, acute hepatitis, or high liver enzymes).
- You are not taking certain medications that interact with doxycycline (such as phenytoin, carbamazepine, barbiturates, warfarin, methotrexate, or cyclosporin).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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