New drug plus amlodipine for high blood pressure and early kidney damage
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests a new medicine (sitogilun malate) combined with a standard blood pressure drug (amlodipine) to see if it protects the kidneys in people with early kidney damage caused by high blood pressure. Participation could help prevent further kidney damage while controlling your blood pressure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years old or older.
- You have mild to moderate high blood pressure (called Grade 1 or Grade 2 hypertension), usually with a top number (systolic) between 140–179 and a bottom number (diastolic) between 90–109.
- You have a small amount of protein in your urine (called microalbuminuria), detected by a urine test showing a UACR between 15 and 30 mg/g.
- You have not had serious heart problems (like heart failure, heart attack, or unstable angina) within the last 6 months.
- You do not have kidney disease from causes other than high blood pressure (like diabetes or autoimmune diseases).
- You are not taking certain medications that could affect blood pressure, such as antidepressants, oral contraceptives, steroids, or NSAIDs (ibuprofen/naproxen).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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