Clinical trials
Adaptation clinical trials
Below are recruiting adaptation clinical trials, each written for real people, not researchers. We’re tracking 654 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03322995RecruitingPhase 2
Neoadjuvant chemo study for resectable pancreatic cancer
This Phase 2 trial tests a chemotherapy plan given before surgery (called “neoadjuvant” treatment) for people with pancreatic adenocarcinoma that looks resectable or borderline resectable on scans. The goal is to see how well this adaptive chemotherapy approach works and whether it can improve outcomes before an operation.
Milwaukee, WisconsinAges 18 years+ - NCT03482245Recruiting
Study how body clock proteins affect immune responses in infections
This study looks at how your body’s daily “clock” proteins may influence your immune response during certain serious infections requiring hospital care. If you qualify, researchers will compare immune signals during treatment to better understand what could improve care.
St Louis, MissouriAges 18–65 - NCT03577041Recruiting
Cost study of eye injections for new macular degeneration
This study evaluates the cost-effectiveness of three anti-VEGF eye injection treatments (bevacizumab, ranibizumab, or aflibercept) for patients with newly diagnosed age-related macular degeneration affecting the center of vision. The research aims to understand which treatment option provides the best medical and financial value in France.
AmiensAges 18–70 - NCT03617133RecruitingPhase 2
MRI-guided radiation plus chemo for cervical cancer
This trial tests a more precise way to deliver radiation for locally advanced cervical cancer using MRI guidance during treatment, along with chemotherapy. It may help shrink tumors more effectively while aiming to reduce side effects by targeting the right areas.
ViennaAges 18–99 - NCT03806283Recruiting
Study how pregnancy blood vessels change in late pregnancy
This study looks at how blood vessels adapt during late pregnancy, especially around the time of a C-section. Your participation may help researchers understand normal pregnancy changes and how they differ in certain complications.
Madison, WisconsinAges 18–40 - NCT03951467Recruiting
Health literacy support to help you follow medical advice
This study tests whether a communication tool matched to your health literacy level can improve how well people follow medical recommendations after an acute episode. It may help you understand your care plan and take the right next steps at home.
BronAges 18 years+ - NCT03970447RecruitingPhase 2/Phase 3
Testing several treatment options for new or returning glioblastoma
This trial studies different treatment regimens for people with glioblastoma that is either newly diagnosed or has come back. It aims to find which treatment approach works best for controlling the tumor and improving outcomes.
Birmingham, AlabamaAges 18 years+ - NCT04129021Recruiting
Eye imaging test with fast detailed scans
This trial studies whether a new, very high-resolution and high-speed eye scan can be used for people with eye problems or for healthy volunteers. It may help doctors better “see” eye structures more clearly to guide care.
ParisAges 18 years+ - NCT04142697Recruiting
Study of how you feel motion with sight and balance
This study looks at how people with normal health—and people with balance (vestibular) loss—perceive motion using their eyes and inner ear. You may help researchers understand how vision and balance systems work together.
Rochester, New YorkAges 18–80 - NCT04171323Recruiting
Active mind training to improve thinking and delay dementia
This study tests an “active mind” computer-based program to help improve thinking skills and possibly slow the process toward dementia. You may be randomly assigned to different program options to see which approach works best for your goals.
San Francisco, CaliforniaAges 55–89 - NCT04302870RecruitingPhase 2/Phase 3
Test medicines for motor neurone disease using adaptive trial design
This study tests treatments for motor neurone disease (MND) and assigns people to different treatment arms in an adaptive way. It may help doctors find out which medicine works best and for whom.
Portadown, County ArmaghAges 18 years+ - NCT04318899Recruiting
Studying who benefits in a specific borderline personality therapy program
This study looks at which factors predict how people do over time and how well they respond to a therapy program for borderline personality disorder. If you have a history of repeated self-harm, your experiences may help researchers understand who is most likely to improve—and why.
Oslo, OsloAges 12–70 - NCT04389437Recruiting
Eye imaging study for people with memory problems
This study uses detailed eye scans to look for changes that might relate to memory problems. You may be able to join if you are being seen for memory concerns and meet the health and eye-scan requirements.
ParisAges 18 years+ - NCT04396002Recruiting
Study of life movement and vision loss in older adults
This study looks at whether how far and how much you move around each day is linked to glaucoma and vision field loss in older adults. It may help researchers understand what affects vision changes over time.
Birmingham, AlabamaAges 18–100 - NCT04424719Recruiting
Follow-up study for high-risk eye melanoma after treatment
This study follows people with high-risk uveal (eye) melanoma after their initial treatment to better understand relapse risk. It may help your care team track you more closely using scheduled visits and blood tests.
ParisAges 18 years+ - NCT04495088RecruitingPhase 3
Before vs after chemotherapy for locally advanced rectal cancer
This Phase 3 study compares giving chemotherapy before rectal surgery versus giving it after surgery, using a tailored plan based on your risk. The goal is to see which timing helps more people with locally advanced rectal cancer stay cancer-free and live longer.
MannheimAges 18 years+ - NCT04554277Recruiting
Blood test-guided care for people hospitalized with heart failure
This study checks whether using a specific blood test (called sST-2) to guide heart-failure treatment leads to better care and outcomes. It may help by tailoring treatment decisions based on your test results.
Montpellier, OccitanieAges 18 years+ - NCT04582903Recruiting
Send-in sample collection study for immune response to respiratory viruses
This study collects sent-in samples to better understand how your immune system responds during a COVID-19–like illness and after you recover. It may help researchers learn why some people get sick and others stay uninfected, and how immune protection works over time.
Rockville, MarylandAges 1 day–99 years - NCT04606849Recruiting
Pilot ePNa tool for pneumonia decisions in urgent care
This trial tests and rolls out an electronic support tool (ePNa) to help urgent care clinicians decide how to evaluate and manage pneumonia. It may help by standardizing decision-making so patients get more consistent care.
American Fork, UtahAges 12 years+ - NCT04670029RecruitingPhase 3
Testing an APA program to improve outcomes in large B-cell lymphoma
This Phase 3 trial studies whether an APA program (an added supportive program during care) can improve event-free survival for people with diffuse large B-cell lymphoma. It may help by supporting patients during standard first-line treatment so they do better over time.
BesançonAges 65 years+ - NCT04681534Recruiting
Testing safer adaptive deep brain stimulation for Parkinson’s
This trial studies an “adaptive” form of deep brain stimulation (DBS) that adjusts based on brain signals, and is mainly done when the DBS battery (IPG) needs replacement or when people are getting DBS for the first time. It aims to improve safety and effectiveness for Parkinson’s symptoms by using recorded brain activity during treatment.
MilanAges Any age - NCT04683315RecruitingPhase 2
Pancreatic cancer biopsy-guided chemo before surgery
This trial uses a special gene test on fluid taken from an endoscopic ultrasound (EUS) biopsy to help choose chemotherapy before surgery for pancreas cancer. It aims to see if this approach improves outcomes by matching treatment to the tumor’s RNA pattern.
Scottsdale, ArizonaAges 18 years+ - NCT04708587Recruiting
Choosing the right anti-platelet duration for advanced kidney disease
This study looks at the best length of anti-platelet medicine (which helps prevent stent clots) after a new type of heart stent. It specifically focuses on people with advanced chronic kidney disease, where bleeding and clot risks can be higher.
SeoulAges 19–84 - NCT04771806Recruiting
MRI-guided adaptive radiation for high-grade brain tumors
This study uses repeated MRI scans with a contrast dye to help doctors tailor (adapt) your radiation treatment over time for a high-grade glioma. It may help improve how accurately radiation targets the tumor as it changes.
Houston, TexasAges 18 years+
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Common questions
- Are there clinical trials for adaptation?
- Yes. Clin2 currently lists 654 recruiting adaptation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adaptation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adaptation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.