Clinical trials
Adaptation clinical trials
Below are recruiting adaptation clinical trials, each written for real people, not researchers. We’re tracking 654 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05344274RecruitingPhase 4
Eye blood flow study in people with glaucoma
This study measures how blood flows in the retina and how well the eye regulates that flow. It compares people with early or very early glaucoma to people without glaucoma to see what differences may predict progression.
Baltimore, MarylandAges 18–88 - NCT05348486Recruiting
Adaptive radiation planning using FMISO imaging for head and neck cancer
This trial tests a way to personalize radiation treatment using a special scan (FMISO) to improve targeting in certain head and neck cancers. It is designed for people who are newly diagnosed and ready for standard curative (definitive) chemoradiation or faster radiation schedules.
BrnoAges 18 years+ - NCT05354765Recruiting
Collect immune cells by lymphapheresis to study cancer response
This trial studies how changing your immune system (with earlier treatments) affects cancer by collecting immune cells from your blood using a process called lymphapheresis. It may help researchers find better ways to monitor immune-related responses and side effects.
ParisAges 18 years+ - NCT05387603RecruitingPhase 3
Targeted radiation for certain advanced neuroendocrine tumors
This Phase 3 study tests whether a targeted radiation treatment approach (using a special “PRRT” scan-guided method) works better to control advanced neuroendocrine tumors. It’s designed for tumors that show strong targeting on a specific PET scan and that are growing despite prior treatment (with some limits).
GothenburgAges 18 years+ - NCT05406856Recruiting
Adaptive proton therapy for cervical cancer with chemo
This trial tests whether an “adaptive” type of radiation planning using proton therapy and MRI-guided brachytherapy can improve treatment for people with cervical cancer. It aims to deliver curative treatment more precisely while still combining it with chemotherapy (cisplatin) when appropriate.
LeidenAges 18 years+ - NCT05440851Recruiting
Testing different treatments for severe breathing failure in ICU
This platform trial studies which treatment works best for adults with sudden, severe breathing failure needing oxygen or a breathing machine in the ICU. It may help patients by matching them to the most appropriate treatment strategy and tracking outcomes to improve care.
Tucson, ArizonaAges 18 years+ - NCT05475600Recruiting
Biofeedback and relaxation for ICU patients with blood cancers
This trial tests whether guided biofeedback and relaxation techniques can help people with blood cancers while they are in the ICU. It may improve comfort and stress during critical illness, compared with standard care.
MetzAges 18–75 - NCT05487807RecruitingPhase 1
Quit-smoking program for people with HIV in Uganda and Zambia
This study tests a tailored quit-smoking (tobacco cessation) program for people living with HIV in Uganda and Zambia. It aims to help you reduce or stop tobacco use in a way that fits your needs and local setting.
KampalaAges 18 years+ - NCT05501665RecruitingPhase 1/Phase 2
Adaptive radiation plus pembrolizumab for stage IV lung cancer
This trial tests a personalized (“adaptive”) radiation plan combined with pembrolizumab, and possibly chemotherapy, for advanced stage IV lung cancer. It aims to improve cancer control while carefully managing side effects, including in patients with certain brain metastases.
Nashville, TennesseeAges 18 years+ - NCT05525962Recruiting
Study factors that affect development in foster children
This study looks at how different stress and support factors may influence how children and teens grow and cope while they are involved with child protective services. It may help clinicians understand what supports work best for children in care.
CanteleuAges Up to 16 years - NCT05544084Recruiting
Patient navigation program for cervical screening in Senegal
This study tests a patient “navigator” approach to improve cervical cancer screening and prevention access in Senegal. You may be invited to help through community education, health facility work, or by being part of a screening-support household.
DakarAges 25–69 - NCT05619185Recruiting
Online program to help couples reduce risky drinking
This study tests an adaptive (tailored) online program to help service members and their partners cut down risky alcohol use. It also focuses on whether couples can practice healthier communication and coping skills while feeling safe together.
Palo Alto, CaliforniaAges 18 years+ - NCT05626114RecruitingPhase 2
Study of a lab-made eye treatment after subretinal surgery
This Phase 2 study tests OpRegen, a treatment delivered during special eye surgery, for geographic atrophy related to age-related macular degeneration (GA from AMD). It also includes an imaging “substudy” that uses detailed pictures of your retina to better track safety and activity.
Beverly Hills, CaliforniaAges 50 years+ - NCT05633056Recruiting
Testing TB medicines for people with drug-resistant TB and HIV
This trial studies a treatment plan for people who have both drug-resistant tuberculosis (TB) and HIV. It focuses on starting a specific TB medication (bedaquiline) and, if needed, HIV treatment soon after enrollment to see what approach works best.
Durban, KwaZulu-NatalAges 18 years+ - NCT05641116Recruiting
Exercise plus education program for long-lasting Lyme-related symptoms
This trial tests whether a combined program of adapted exercise and therapeutic education can improve long-lasting symptoms that are thought to be related to Lyme disease. It may help people who have symptoms for over 6 months and are not very active currently.
Clermont-FerrandAges 18 years+ - NCT05651828RecruitingEarly Phase 1
Tested adaptive dosing of vismodegib for advanced skin cancer
This trial tests an adaptive (adjusted) dosing plan using vismodegib for people with advanced basal cell carcinoma. It may help control the cancer while balancing side effects, and your team will closely monitor how your tumors respond.
Tampa, FloridaAges 18 years+ - NCT05686473Recruiting
Parent teaching program for children with prenatal alcohol exposure
This study offers a structured teaching program for parents of children who were exposed to alcohol before birth (prenatal alcohol exposure). It aims to help families better understand the child’s needs and how to support development and daily functioning.
ArendalAges 2–18 - NCT05723471Recruiting
Physical activity program for newly diagnosed cancer patients
This trial studies whether a structured exercise (physical activity) program started soon after a new cancer diagnosis is safe and helpful. You may benefit if you can safely do activity and meet key health measures.
Nancy, FranceAges 18 years+ - NCT05743699Recruiting
Bright Horizons program for Native teens with recent binge drinking
This study tests the Bright Horizons program to help Native American youth who recently had a binge alcohol event. It looks at whether support and skills can reduce risky drinking and improve safety and wellbeing.
Whiteriver, ArizonaAges 10–24 - NCT05773144Recruiting
Exercise program during chemotherapy for colon cancer recovery
This trial tests an aerobic exercise plan during chemotherapy for people with stage II or III colon cancer. It compares different exercise approaches to see if exercise can be done safely and may improve how you tolerate treatment and recovery.
Oakland, CaliforniaAges 18 years+ - NCT05780853Recruiting
Game-based testing for young children’s learning and communication
This trial uses a simple, game-like assessment to better understand how young children develop and learn. It may help by creating or improving tools that track development and identify needs earlier.
LondonAges 3–8 - NCT05786898Recruiting
Test a computer training program to improve autism-related thinking
This study tests a computerized “cognitive remediation” program adapted for people with autism, using social scenarios and skills. The goal is to improve thinking and related day-to-day abilities by practicing structured tasks on a screen.
ParisAges 13–40 - NCT05800899Recruiting
Brief counseling program for alcohol-related injuries in Latinxs
This trial tests a culturally tailored, short counseling session for people who are Latinx and have alcohol-related injuries. It aims to reduce health disparities by helping improve treatment access and outcomes after an injury.
El Paso, TexasAges 18 years+ - NCT05806801Recruiting
Study how weight loss changes the body with or without exercise
This study looks at how your metabolism (how your body uses energy and controls blood sugar/fats) changes during weight loss, comparing weight loss alone versus weight loss plus exercise. It may help researchers understand what body changes happen with different approaches and why.
Ann Arbor, MichiganAges 18–40
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Common questions
- Are there clinical trials for adaptation?
- Yes. Clin2 currently lists 654 recruiting adaptation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adaptation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adaptation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.