Clinical trials
Adaptation clinical trials
Below are recruiting adaptation clinical trials, each written for real people, not researchers. We’re tracking 646 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06541886Recruiting
Online therapy for teens with insomnia
This study tests a type of therapy called cognitive behavioral therapy for insomnia (CBT-I), adapted for teens. The therapy is done online in virtual sessions and aims to help you sleep better without medication.
Indianapolis, IndianaAges 13–18 - NCT06545747RecruitingPhase 3
MRI-guided radiation for advanced lung cancer
This trial tests a new way of giving radiation therapy for advanced lung cancer that cannot be surgically removed. It uses MRI scans to guide and adjust the radiation dose, which may help target the tumor more precisely and reduce side effects.
GuangzhouAges 18–75 - NCT06551441Recruiting
High-intensity interval training for lung disease
This study tests whether short bursts of intense exercise can improve heart and lung function in people with COPD (a chronic lung condition). It aims to see if this type of training is safe and effective.
CopenhagenAges 40–80 - NCT06551844RecruitingPhase 2
Adaptive platform trial for new dengue treatments
This trial tests different experimental drugs to treat dengue early. It aims to find which treatment works best and is safe for patients who start within 48 hours of fever.
Kuala LumpurAges 10 years+ - NCT06561100Recruiting
Optimizing treatment for brain-injured warfighters
This trial tests ways to improve treatment for active-duty service members who have had a mild traumatic brain injury (mTBI) and still have symptoms. It aims to find the best approach to help them recover.
Camp Pendleton, CaliforniaAges 18–55 - NCT06568705RecruitingPhase 2
Shorter adaptive radiation for early breast cancer
This trial tests a shorter, more targeted course of daily radiation for early-stage breast cancer. The radiation plan is adjusted each day to better fit your body, which may reduce side effects.
BeijingAges 35–70 - NCT06591676Recruiting
Translating a thinking habits questionnaire into Urdu
This trial is translating a questionnaire about negative thinking patterns (called the Dysfunctional Attitude Scale) into Urdu and testing it with people who have depression or anxiety. The goal is to make sure it works for Urdu-speaking communities in Pakistan.
Lahore, Punjab ProvinceAges 18–65 - NCT06596460Recruiting
Imaging study after TAVI valve replacement
This study collects extra imaging data from 40 people who are already scheduled for a routine TAVI procedure to replace a narrowed aortic heart valve. The goal is to better understand the valve's structure and function using scans.
London, EnglandAges 18 years+ - NCT06352619Recruiting
Lowering blood pressure after clot removal for stroke
This trial tests whether lowering blood pressure soon after a clot-removal procedure for stroke can improve recovery. It is for people whose blood pressure remains high after the procedure.
Sydney, New South WalesAges 18 years+ - NCT06352632RecruitingPhase 3
Adaptive Stroke Trial Testing New Treatments
This trial is testing different treatments for stroke patients to find which work best. It's designed to adapt over time so new treatments can be added as research progresses.
Sydney, New South WalesAges 18 years+ - NCT06444269RecruitingPhase 2
Precision radiation before surgery for early hormone-positive breast cancer
This trial tests a focused radiation treatment before surgery for early-stage breast cancer that is hormone receptor positive and HER2 negative. The goal is to give precise radiation only to the tumor, with the hope of reducing side effects and improving outcomes.
Dallas, TexasAges 18 years+ - NCT06635486Recruiting
Mental health support for Venezuelans in Lima
This study offers mental health support to Venezuelan adults living in Lima who are feeling anxious, depressed, or have experienced trauma. It will check if you have signs of depression, anxiety, or post-traumatic stress and provide help if you do.
LimaAges 18 years+ - NCT06650813Recruiting
Adapting a fatigue program for sickle cell disease
This trial adapts the FACETS program, a fatigue-management course, for people with sickle cell disease. It aims to help participants better cope with fatigue and improve daily life.
GrenobleAges 18 years+ - NCT06689930Recruiting
Blood pressure app study for pregnant Black women
This study tests a mobile app (M•other App) to help pregnant Black women manage or prevent high blood pressure. You'll use the app and participate in improvement cycles with community organizations.
Madison, WisconsinAges 18 years+ - NCT06690788Recruiting
Couples program to prevent type 2 diabetes (PreventT2 Together)
This research study looks at whether a lifestyle program designed for couples can help prevent type 2 diabetes. Both partners take part together, and the program is based on the National Diabetes Prevention Program.
Salt Lake City, UtahAges 18 years+ - NCT06701630Recruiting
Italian study of daily thinking and memory scales
This study is testing new questionnaires to better understand everyday thinking and memory problems in older adults. It aims to improve how doctors identify and track conditions like mild cognitive impairment and early dementia.
Milan, MichiganAges 60 years+ - NCT06706349Recruiting
Exercise to improve sleep in alcohol use disorder
This study tests whether a personalized exercise program can improve sleep quality in people with alcohol use disorder. You would work with a physical activity coach over several weeks, and your sleep and health would be monitored closely.
BesançonAges 18–65 - NCT07685483Recruiting
Drama therapy for well-being in obesity and weight-loss care
This trial tests whether drama therapy can improve psychological and social well-being for people with obesity or those in bariatric care. It compares drama therapy sessions with standard care to see if it helps with emotional health and social connections.
Blendecques, Hauts-de-FranceAges 18 years+ - NCT07687147Recruiting
Daily adjusted radiation dose for abdominal and pelvic tumors
This trial tests a new way to give radiation therapy for tumors in the belly or pelvis. Doctors will use daily MRI scans to adjust the radiation dose, aiming to better protect nearby organs while still treating the cancer.
Zurich, Canton of ZurichAges 18 years+ - NCT07406087Recruiting
Navigation support for young adults after cancer
This study tests a navigation program to help cancer survivors ages 21-45 get the follow-up care they need. It may be a good fit if you were diagnosed with certain cancers as a teen or young adult.
Pasadena, CaliforniaAges 21–45 - NCT07377383Recruiting
Exercise for heart health in postmenopausal women
This study tests how different exercise routines affect heart and metabolic health in women after menopause. It may help if you are already active, have few heart risk factors, and are not on hormone therapy.
Oleiros, A CoruñaAges 46–65 - NCT06834152Recruiting
Online adaptive radiation for localized prostate cancer
This trial tests a new way to deliver high-precision radiation to the prostate using daily MRI or CT scans to adjust the treatment based on your exact anatomy. It aims to make radiation more accurate and reduce side effects.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT06747442Recruiting
Native moms' recovery program during pregnancy
This study offers support for Native American and Alaska Native pregnant women who want recovery from substance use. The program connects you with your culture and community to help you and your baby.
Salt Lake City, UtahAges 18 years+ - NCT06719232Recruiting
Testing a new way to give bladder treatment without a catheter
This study tests a catheter-free method for delivering medication directly into the bladder. It may help patients with bladder pain, recurrent infections, bladder cancer, or cystitis after radiation or chemotherapy.
BudapestAges 18–80
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Common questions
- Are there clinical trials for adaptation?
- Yes. Clin2 currently lists 646 recruiting adaptation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adaptation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adaptation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.