Clinical trials
Addiction Disorders clinical trials
Below are recruiting addiction disorders clinical trials, each written for real people, not researchers. We’re tracking 101 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04379115Recruiting
Brain stimulation study for people with opioid addiction
This study tests a non-invasive brain stimulation approach to reduce opioid cravings in people who are actively using non-prescribed opioids while on stable methadone. It may help people feel less craving and improve recovery support.
Hinsdale, IllinoisAges 18–85 - NCT05583747Recruiting
Brain stimulation therapy with guidance for treatment-resistant depression
This study tests a type of brain stimulation (guided iTBS) to improve depression when standard antidepressant treatments haven’t helped. It also checks that the treatment is safe for people who can meet the study and scan safety requirements.
Toronto, OntarioAges 18–65 - NCT06675539Recruiting
Testing a tool to predict alcohol withdrawal severity in French speakers
This study tests a French version of a questionnaire (PAWSS) that helps doctors predict how severe alcohol withdrawal might be. It is for people aged 18 to 60 who are dependent on alcohol and planning a supervised detox or being hospitalized for another reason.
ÉtampesAges 18–60 - NCT06731621RecruitingPhase 1
Psilocybin for depression that hasn't responded to treatment in autistic adults
This trial tests whether a single dose of psilocybin can help treat depression in autistic adults who have not gotten better with standard antidepressants. You will be asked to stop your current antidepressant and antipsychotic medications before the study, and you will have several follow-up visits and an MRI scan.
Toronto, OntarioAges 18–65 - NCT02639702RecruitingPhase 4
Switching from twice-daily to once-daily clozapine for schizophrenia
This trial tests whether taking clozapine once a day (instead of twice a day) works safely for people with schizophrenia. It may help by simplifying your dosing schedule while closely monitoring your wellbeing.
Toronto, OntarioAges 18 years+ - NCT05153382Recruiting
Dialectical behavior therapy for youth at bipolar risk
This trial tests whether a structured therapy called dialectical behavior therapy (DBT) helps young people with bipolar disorder or at risk for it, especially with self-harm or risky behaviors. It may help by teaching coping skills and improving safety and emotional control.
Toronto, OntarioAges 13–23 - NCT05627492Recruiting
DBT booster sessions for youth at bipolar risk
This study adds short “booster” sessions to Dialectical Behavior Therapy (DBT) for young people who already took part in a prior DBT study, including those with bipolar symptoms or strong family risk. It aims to see if extra DBT support helps mood and coping over time.
Toronto, OntarioAges 14–25 - NCT07523633RecruitingPhase 2
Semaglutide to help reduce cannabis use disorder
This trial tests whether a medication called semaglutide (used for weight management) can help adults with cannabis use disorder cut down or stop using cannabis. Researchers want to see if it reduces cravings and use while also monitoring overall health.
FrederiksbergAges 18–70 - NCT07273955Recruiting
Alcohol use and weight-loss surgery: a study of addiction follow-up
This study looks at how alcohol use disorder changes after weight-loss surgery. Researchers want to understand the link between eating disorders, alcohol problems, and addiction treatment before and after surgery.
StrasbourgAges 18 years+ - NCT05033028RecruitingPhase 3
Using a smartphone to support opioid addiction recovery
This Phase 3 study tests whether using smartphones can help people with opioid-use disorder stick with treatment and recover more successfully. It focuses on people starting or already in treatment using methadone or buprenorphine, with support delivered through the study app or messages.
Piscataway, New JerseyAges 18–85 - NCT05489068Recruiting
Motivational interviewing approach for people starting addiction treatment
This study compares two ways of having conversations when you begin outpatient addiction treatment. It tests whether a motivational interviewing style at intake improves your engagement and involvement in your care.
Albuquerque, New MexicoAges 18 years+ - NCT06799117Recruiting
Decision Support for Opioid Addiction Treatment
This study tests a new way to help people in the emergency department who have moderate to severe opioid use disorder. It looks at using a decision-support tool to guide treatment choices.
Guilford, ConnecticutAges 18 years+ - NCT06370481Recruiting
HIV and addiction training program for Alabama clinics
This study tests a program to help people living with HIV in Alabama who also struggle with opioid or stimulant use. It takes place at your HIV clinic and checks whether a new approach to addiction care can improve your health.
Birmingham, AlabamaAges 18 years+ - NCT05529927RecruitingPhase 2
Dexamphetamine given long-acting to reduce cocaine use
This Phase 2 study tests whether a long-acting form of dexamphetamine can reduce cocaine use in people with moderate to severe cocaine use disorder. It also checks safety, including heart and mental health side effects, while you attend study visits regularly.
The HagueAges 18 years+ - NCT05859347Recruiting
Brain stimulation study for cannabis use disorder
This trial tests whether a treatment called repetitive transcranial magnetic stimulation (a non-surgical magnetic stimulation to the brain) can help people reduce or stop cannabis use. You may be eligible if you have cannabis use disorder and meet specific safety and symptom criteria.
Toronto, OntarioAges 18–65 - NCT06105853Recruiting
Stress and brain activity in alcohol use disorder
This study looks at how people with alcohol use disorder respond to stress and what happens in the brain. You'll use a smartphone and may have an MRI scan to understand your stress responses.
Mannheim, Baden-WurttembergAges 18–65 - NCT05992272Recruiting
How cues affect drinking and smoking habits
This study looks at how certain cues (like seeing a drink or a cigarette) trigger cravings and behavior in people who drink alcohol or smoke. Understanding this may help improve addiction treatments.
BerlinAges 16–65 - NCT01392885Recruiting
Brain health and exercise program for schizophrenia
This trial studies how a structured exercise program may affect brain health in people with schizophrenia or schizoaffective disorder. It may help researchers understand whether exercise can support brain function and overall health in this condition.
Vancouver, British ColumbiaAges 19–45 - NCT07558187Recruiting
Health Inequalities Study in Rural and Urban Communities
This research study examines how health differences vary between rural and urban areas and among different groups of people. Researchers want to understand what factors affect health outcomes and why some communities experience worse health than others.
LarissaAges 18 years+ - NCT06457243Recruiting
Brain stimulation for methamphetamine use disorder
This trial tests a type of brain stimulation (called cTBS) to see if it can reduce methamphetamine cravings and improve thinking. If you are in recovery or still using, you may be able to join.
Shanghai, Shanghai MunicipalityAges 18–60 - NCT06370988Recruiting
Theta-burst stimulation for bipolar depression
This study tests a type of brain stimulation (theta-burst TMS) to see if it helps improve depression in people with bipolar disorder. It might be a good option if you have tried medication but still feel depressed.
Toronto, OntarioAges 18–65 - NCT04499079Enrolling by invitation
ADAPT: Youth addiction prevention and treatment programs in local counties
This study tests whether a local program (called the LHS intervention) can improve addiction-related prevention and treatment for young people. You may be able to join if you live in a participating county and use a community mental health center service during the study period.
Indianapolis, IndianaAges 11–22 - NCT06413979Recruiting
Family support program for teens with substance use and mood or anxiety issues
This trial offers a family support program for teens with both substance use and internalizing problems like depression or anxiety. The goal is to help you and your caregiver work together to manage symptoms and improve well-being.
Jacksonville, FloridaAges 13–21 - NCT05142683Recruiting
Test an integrated care plan for teens with depression
This study tests whether a structured, coordinated care pathway helps teens (and their caregivers) manage depression better than usual care. It aims to see if targeted treatment and follow-up improve depression symptoms over time.
Toronto, OntarioAges 13–18
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Common questions
- Are there clinical trials for addiction disorders?
- Yes. Clin2 currently lists 101 recruiting addiction disorders studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a addiction disorders trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a addiction disorders trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.