Clinical trials
Adjuvant clinical trials
Below are recruiting adjuvant clinical trials, each written for real people, not researchers. We’re tracking 576 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06796686RecruitingPhase 1
HIV vaccine safety and immune response study for healthy adults
This trial tests a new two-part HIV vaccine regimen in healthy adults without HIV. The goal is to see if it is safe and produces an immune response that could help prevent HIV.
San Francisco, CaliforniaAges 18–55 - NCT06950814Recruiting
Impact of extra treatment after surgery for liver cancer
This study looks at whether additional treatment after liver surgery (like chemotherapy or radiation) can help people with a rare and aggressive liver cancer called primary hepatic sarcomatoid carcinoma (PHSC). It only includes people who had surgery and no other cancer treatments before that.
Chengdu, SichuanAges 18 years+ - NCT07010419RecruitingPhase 3
Firmonertinib vs placebo for early-stage lung cancer with rare EGFR mutations
This trial tests if Firmonertinib, a targeted pill, can prevent lung cancer from returning after surgery in people with non-small cell lung cancer that has certain uncommon EGFR gene changes. If you have had complete tumor removal and have one of these specific mutations, this study may help you stay cancer-free longer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07371234RecruitingPhase 2
Low-dose radiation and immunotherapy before surgery for head and neck cancer
This trial tests a combination of low-dose radiation and an immunotherapy drug (similar to Keytruda) given before surgery for advanced head and neck cancer. The goal is to see if this approach can shrink tumors and improve outcomes.
GuangdongAges 18–75 - NCT07417397RecruitingPhase 3
TACE after surgery for high-risk liver cancer
This trial tests whether a liver-directed treatment called TACE (transarterial chemoembolization) after surgery can help prevent liver cancer from coming back in people with high-risk features.
NanningAges 18–70 - NCT07417800Recruiting
Predicting liver cancer treatment after surgery
This study uses digital scans of your tumor tissue and CT/MRI images to build a computer model that helps predict whether you might need extra treatment (adjuvant therapy) after liver cancer surgery. The goal is to use your own tissue and scan data to personalize follow-up care.
Hangzhou, ZhejiangAges 18 years+ - NCT05983874Enrolling by invitationPhase 1
Booster HIV vaccine study for those who got the first shots
This study tests two booster doses of an HIV vaccine to see if they are safe and boost the immune system. It is for healthy adults who already received three earlier doses of a related vaccine.
AmsterdamAges 18–51 - NCT05640999RecruitingPhase 2
Trial for early uterine cancer with POLE mutation after surgery
This Phase 2 trial studies an added (adjuvant) treatment for early-stage uterine cancer that has a specific genetic change called POLE mutation and does not have a p53 abnormal pattern. The goal is to lower the risk of the cancer coming back after surgery.
Anchorage, AlaskaAges 18 years+ - NCT04009265RecruitingPhase 3
Compare chemotherapy, chemoradiation, or surgery alone after esophageal surgery
This Phase 3 trial looks at the best next step after surgery for thoracic esophageal squamous cell cancer that has spread to nearby lymph nodes. It compares adding chemotherapy, adding chemoradiation (chemotherapy plus radiation), or not adding additional treatment right away, to see which approach works best and is safest.
Fuzhou, FujianAges 18–75 - NCT04280822RecruitingPhase 3
Immunotherapy plus chemo versus chemo alone before surgery
This Phase 3 trial tests whether adding immunotherapy to chemotherapy before surgery works better than chemotherapy alone for resectable esophageal cancer. The goal is to improve outcomes after tumor shrinkage before the operation.
Zhengzhou, HenanAges 18–75 - NCT04843852RecruitingPhase 1
Test vaccine added to hepatitis B treatment
This early-phase study tests whether a hepatitis B vaccine (with an added ingredient to boost the immune response) can safely help people with long-term hepatitis B who are already on antiviral therapy. It is mainly looking at safety and how the immune system responds.
Baltimore, MarylandAges 18 years+ - NCT04875585RecruitingPhase 2
Neoadjuvant and post-surgery immunotherapy for operable lung cancer
This trial tests a combination of medicines given before surgery and immunotherapy after surgery for resectable non-small cell lung cancer (NSCLC). It aims to shrink the tumor before the operation and reduce the risk of cancer coming back after surgery.
Innsbruck, TyrolAges 18 years+ - NCT05277688RecruitingPhase 3
Radiation alone versus added chemotherapy after cervical cancer surgery
This trial compares standard radiation to radiation plus chemotherapy after surgery for early-stage cervical cancer. It aims to lower the chance the cancer comes back in patients considered higher risk based on their surgical pathology.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT05292742RecruitingPhase 2
Continue targeted breast cancer therapy or switch to a new combo
This Phase 2 study compares two treatment plans after breast surgery when cancer did not fully disappear before surgery. It tests whether adding trastuzumab, pyrotinib, and capecitabine works better than continuing the original targeted therapy.
Fuzhou, FujianAges 18–75 - NCT05462106RecruitingPhase 1/Phase 2
ACI-24.060 study for early Alzheimer’s in adults and Down syndrome
This Phase 1/2 study tests an Alzheimer’s treatment called ACI-24.060 to see if it affects the disease in people with early Alzheimer’s changes. It includes two groups: older adults with early symptoms and people with Down syndrome who also show Alzheimer’s-related changes on brain scans.
Phoenix, ArizonaAges 35–85 - NCT05516628RecruitingPhase 2
Adjuvant atezolizumab plus bevacizumab after liver cancer surgery
This trial studies whether adding atezolizumab and bevacizumab after complete liver cancer surgery can lower the chance the cancer comes back. It also uses “multi-omics” tests (special lab tests on your tissue/blood) to help predict who is more likely to respond or resist treatment.
SingaporeAges 21–90 - NCT05534087RecruitingPhase 3
Blood test guided chemo after colon cancer surgery
This study tests whether giving additional (adjuvant) chemotherapy based on a special blood test—circulating tumor DNA (ctDNA)—can lower the risk of colon cancer coming back. It targets people with stage II–III colon cancer whose blood test is positive for minimal residual disease (MRD) after completing standard chemo.
GoyangAges 19–75 - NCT05536505RecruitingPhase 2
After-surgery targeted pill to prevent relapse in EGFR lung cancer
This Phase 2 trial studies whether an EGFR-targeted pill, given after surgery, can reduce the chance of lung cancer coming back. It specifically looks at people whose tumors have certain EGFR changes and where “minimal residual disease” (tiny leftover cancer) is being used to guide treatment.
BeijingAges 18–80 - NCT05593458RecruitingPhase 3
Stomach cancer surgery before chemo: artery-based or drip chemo
This trial compares two ways of giving chemotherapy before surgery for locally advanced stomach or stomach–esophagus cancer: chemo sent through an artery versus chemo given through an IV line. It also studies adding PD-1 immunotherapy to see which approach works better and is safer.
Hangzhou, ZhejiangAges 18–75 - NCT05595408Recruiting
Tracking tumor DNA to predict relapse after upper kidney cancer surgery
This study checks tumor DNA found in blood and urine to see who is at higher risk of the cancer coming back after surgery. It may help doctors identify “minimal residual disease,” meaning tiny amounts of cancer that can remain after treatment.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05692674RecruitingPhase 2
Proton radiation after breast surgery with implant reconstruction
This trial studies a type of radiation made with proton beams given after mastectomy and implant reconstruction to lower breast cancer coming back. It’s for people who need additional (adjuvant) radiation and have not had prior radiation to the chest or breast.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT05731258Recruiting
Watch how liposomal doxorubicin is used after breast cancer
This is an observational study that follows people receiving add-on (adjuvant) chemotherapy after primary breast cancer. It aims to understand treatment patterns and outcomes for patients healthy enough to receive liposomal doxorubicin and who have no major complications.
Hangzhou, ZhejiangAges 18–75 - NCT05735145RecruitingPhase 3
Chemo plus radiation, then extra chemo for advanced cervical cancer
This Phase 3 study looks at whether adding chemotherapy after standard chemo-radiation can improve outcomes for advanced cervical cancer. You might be eligible if your cancer responded fully to initial treatment and you meet safety and health requirements.
Liuzhou, GuangxiAges 18–75 - NCT05760612RecruitingPhase 3
After breast cancer surgery, test neratinib plus trastuzumab
This trial studies whether adding neratinib to standard trastuzumab treatment after neoadjuvant (before-surgery) therapy lowers the risk of breast cancer coming back. It is for people whose breast cancer is hormone-receptor positive and HER2 positive, with residual cancer found after neoadjuvant treatment.
GuangzhouAges 18–70
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Common questions
- Are there clinical trials for adjuvant?
- Yes. Clin2 currently lists 576 recruiting adjuvant studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adjuvant trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adjuvant trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.