Clinical trials
Adolescence clinical trials
Below are recruiting adolescence clinical trials, each written for real people, not researchers. We’re tracking 958 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06527300RecruitingPhase 2
Study of NHWD-870 for advanced NUT cancer
This trial tests a new drug called NHWD-870 for people with NUT cancer (a rare cancer linked to a gene change). The goal is to see if the drug can help shrink tumors or slow the cancer's growth.
ChongqingAges 12–75 - NCT06449014Recruiting
Mini-implant palate expander for teens and adults
This study tests whether a new type of palate expander that uses small implants (mini-screws) can safely widen the upper jaw in people 16 and older. It may be an option for you if your upper jaw is too narrow, even if you have already stopped growing.
Anderlecht, Brussels CapitalAges 16 years+ - NCT06458920Recruiting
How friends help teens manage emotions
This study looks at how teens and young adults learn to manage their emotions. If you fit the age range and are healthy enough for an MRI, you may help us understand how social situations affect emotion regulation.
Los Angeles, CaliforniaAges 13–25 - NCT06476886Recruiting
Comparing two hospital units for teens in crisis
This trial tests a new way to help teenagers who are in a mental health crisis with suicidal thoughts. It compares two different hospital units to see which one works better for teens and their families.
Columbus, OhioAges 12–17 - NCT06465381Recruiting
Suicide prevention program for teens in Mozambique schools
This trial tests a safety planning and therapy program to help teens with suicidal thoughts. It is for students in certain schools in Mozambique.
BeiraAges Any age - NCT06203899Recruiting
Depression and suicide prevention for teens in special schools
This study tests a program to prevent depression and suicide in teens at special schools. It helps if you've had some symptoms but aren't already getting treatment.
Boekel, Noordoost BrabantAges 12–18 - NCT06273137Recruiting
Positive affect treatment for teens with early adversity
This trial tests a treatment designed to improve positive emotions in adolescents who have experienced stressful early life events. It may help your teen build resilience and emotional wellbeing.
Irvine, CaliforniaAges 12–16 - NCT05981677Recruiting
Social feedback and risk-taking in teens who self-harm
This study uses a brain scan (MRI) to understand how teens who self-harm respond to social feedback. It aims to learn more about why some teens take risks that may be harmful.
Chengdu, SichuanAges 15–18 - NCT06087341RecruitingPhase 1
CAR T-Cell Therapy for Advanced Sarcoma in Young People
This trial tests a special type of immune cell (called a CAR T-cell) that is trained to attack sarcoma cells. It is for children, teens, and young adults up to age 40 whose sarcoma has not responded to standard therapy. The treatment is given directly into the tumor, and the goal is to see if it is safe and how well it works.
MadridAges Up to 30 years - NCT05926804Recruiting
Screening and treatment for Helicobacter pylori in teens
This trial checks teenagers for a long-lasting H. pylori stomach infection and then treats those who need it. It may help prevent ongoing stomach problems from the infection and compare outcomes between treated and non-treated groups.
CoyhaiqueAges 14–18 - NCT06015191Recruiting
Remote heart rehab for teens with congenital heart disease
This trial tests a home-based cardiac rehab program for adolescents with certain types of congenital heart disease. It aims to help you exercise safely and improve your fitness using online coaching and monitoring.
Kansas City, MissouriAges 12–19 - NCT05921201Recruiting
RRE program to prevent depression in Chinese American teens
This trial tests an education and skills program (Relax, Reflect, and Empower, or RRE) designed to help prevent depression in Chinese American teens. It may help by teaching coping strategies before symptoms become more serious.
Boston, MassachusettsAges 14–18 - NCT06124846Recruiting
Cannabis break and brain changes in teens
This study looks at what happens in the brain when teens with cannabis use disorder stop using cannabis for 6 weeks. It uses MRI scans to see changes in areas that control habits and decisions.
Minneapolis, MinnesotaAges 15–18 - NCT05748730Recruiting
Care team support program for teens at risk of depression
This study tests an “integrated care” program that supports teens who are dealing with depression symptoms or recent suicidal thoughts. It also involves a parent or caregiver to help improve support at home and connect teens to the right help.
Gibbsboro, New JerseyAges 12–18 - NCT05859126Enrolling by invitation
Choline supplement study on teens’ learning and thinking
This study follows children of mothers who previously took a choline supplement, and it tests how those children think and learn when they reach age 13. It looks at whether earlier choline intake during pregnancy is linked to better or different thinking skills in adolescence.
Ithaca, New YorkAges 13–13 - NCT05768217Recruiting
Community program for teens and adults in participating neighborhoods
This study tests a community resiliency program to help people cope and thrive. It includes teens (13+) and adults living in specific neighborhoods chosen for the study.
Pittsburgh, PennsylvaniaAges 13 years+ - NCT05774002Recruiting
Psychological check-in for teens getting back surgery for scoliosis
This study asks teens with idiopathic scoliosis to complete psychological assessments while planning for elective back surgery. It may help doctors better understand patients’ mental and emotional needs around surgery.
The Bronx, New YorkAges 10–19 - NCT05652153Recruiting
Brain-signal study for teens with depression and suicide thoughts
This study looks at how certain brain “inhibitory” signals work in teenagers and young adults who have depression and either suicide thoughts or past suicide behavior. The goal is to better understand suicide risk and what might help reduce it, using brain and brainwave testing.
Minneapolis, MinnesotaAges 13–21 - NCT05796531Recruiting
Reduce self-harm urges after hospital stay using new skills
This trial tests a learning-based therapy (called therapeutic evaluative conditioning) to reduce adolescents’ thoughts and behaviors related to self-injury during and after a psychiatric inpatient hospital stay. It may help some teens feel less pulled toward self-harm after leaving the hospital.
Brighton, MassachusettsAges 12–19 - NCT05732779Recruiting
App-based check-ins to help teens take transplant medicines
This study tests a phone app that uses video check-ins (called directly observed therapy) to help adolescent heart-transplant patients take their immunosuppression medicines as prescribed. It may help reduce missed doses, which is important for protecting the transplanted heart.
Coral Gables, FloridaAges 10–21 - NCT05706376Recruiting
Family support program for Palestinian teens and parents
This study tests an evidence-based family support program that involves parents and adolescents together. It may help families improve support and wellbeing by giving structured guidance and group-based sessions.
Notre Dame, IndianaAges 12–75 - NCT05584449Recruiting
After-cancer group program for young adult survivorship goals
This trial offers a structured group curriculum to help young adults after cancer treatment manage survivorship concerns and improve outcomes. You may be eligible if you finished curative cancer treatment recently and can fully join all six group meetings.
Scottsdale, ArizonaAges 18–39 - NCT05558566Recruiting
Neurofeedback training for Tourette-related tics in teens
This study tests whether brain training using “neurofeedback” can reduce Tourette syndrome tics in children ages 10–16. It compares an active neurofeedback condition to a control condition while measuring brain activity with an MRI.
New Haven, ConnecticutAges 10–16 - NCT05463120Enrolling by invitation
Follow-up study of early growth and puberty timing
This study follows families from an earlier infant feeding study to better understand what affects when puberty starts. It looks at growth and hormone-related health information to explain differences in pubertal development.
Bethesda, MarylandAges 8–100
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Common questions
- Are there clinical trials for adolescence?
- Yes. Clin2 currently lists 958 recruiting adolescence studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adolescence trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adolescence trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.