Clinical trials
Adolescence clinical trials
Below are recruiting adolescence clinical trials, each written for real people, not researchers. We’re tracking 932 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05654012Recruiting
Study of migraine risk in teens and kids
This study looks at how migraine may start or affect children by comparing young people who either have migraine symptoms or are at higher risk. It may help researchers understand migraine patterns and who could benefit from early prevention.
St Louis, MissouriAges 10–13 - NCT05662280Recruiting
Brain stimulation study for teens with ADHD and memory trouble
This study tests whether changing brain activity can improve working memory in teens who have ADHD and trouble remembering and holding information in mind. You and your parent will answer questionnaires, and brain imaging/brain-stimulation testing (MRI/TMS) may be used, with compensation for each session.
East Providence, Rhode IslandAges 12–18 - NCT05652153Recruiting
Brain-signal study for teens with depression and suicide thoughts
This study looks at how certain brain “inhibitory” signals work in teenagers and young adults who have depression and either suicide thoughts or past suicide behavior. The goal is to better understand suicide risk and what might help reduce it, using brain and brainwave testing.
Minneapolis, MinnesotaAges 13–21 - NCT05609630RecruitingPhase 3
Testing two medicines for active systemic juvenile arthritis
This Phase 3 trial studies how well upadacitinib (a pill) and tocilizumab (a shot/IV medicine) improve symptoms and inflammation in children with active systemic juvenile idiopathic arthritis (sJIA). It also looks at side effects and how these medicines move through the body.
Phoenix, ArizonaAges 1–17 - NCT05609916Recruiting
CBT therapy to help kids stop OCD medicine
This trial studies whether adding structured talk therapy (CBT) can help some children with obsessive-compulsive disorder (OCD) reduce and potentially stop their OCD medicine. It’s designed for kids who are still having meaningful symptoms despite being on an OCD medication long enough.
Houston, TexasAges 7–17 - NCT05617495Recruiting
Mindfulness training with brain scans for depression
This study tests a mindfulness-based program combined with “brain scan feedback” (fMRI neurofeedback) to see if it can help teenagers and young adults with major depression. It may help by teaching skills and tracking brain activity changes during treatment.
Boston, MassachusettsAges 13–18 - NCT05584449Recruiting
After-cancer group program for young adult survivorship goals
This trial offers a structured group curriculum to help young adults after cancer treatment manage survivorship concerns and improve outcomes. You may be eligible if you finished curative cancer treatment recently and can fully join all six group meetings.
Scottsdale, ArizonaAges 18–39 - NCT05558566Recruiting
Neurofeedback training for Tourette-related tics in teens
This study tests whether brain training using “neurofeedback” can reduce Tourette syndrome tics in children ages 10–16. It compares an active neurofeedback condition to a control condition while measuring brain activity with an MRI.
New Haven, ConnecticutAges 10–16 - NCT05588648RecruitingPhase 1/Phase 2
Vactosertib for recurrent or progressive bone cancer
This trial tests a new drug called vactosertib for people with a type of bone cancer called osteosarcoma that has come back or hasn't responded to other treatments. The goal is to see if the drug can help shrink or slow the cancer and to check its safety.
Cleveland, OhioAges 12 years+ - NCT05463120Enrolling by invitation
Follow-up study of early growth and puberty timing
This study follows families from an earlier infant feeding study to better understand what affects when puberty starts. It looks at growth and hormone-related health information to explain differences in pubertal development.
Bethesda, MarylandAges 8–100 - NCT05431088RecruitingPhase 2/Phase 3
Study of osivelotor for sickle cell disease
This study tests an investigational medicine called osivelotor for people with sickle cell disease (SCD). The goal is to see if it can reduce pain crises and improve overall health. It is for adults and adolescents aged 12 and older.
Mobile, AlabamaAges 12 years+ - NCT05427123Recruiting
Study for kids and teens with bipolar or cyclothymic disorder
This trial is testing treatments for children and teens (ages 9–19) who have been diagnosed with bipolar disorder or cyclothymic disorder. It also requires regular participation from a caregiver so the team can track symptoms and response over time.
Los Angeles, CaliforniaAges 9–19 - NCT05277558Recruiting
MRI and brain testing in teens at risk for type 2 diabetes
This study looks at brain health in teens with normal weight, overweight, or obesity who are at risk for type 2 diabetes. It may help researchers understand how weight and diabetes risk affect the brain, using MRI scans and learning/memory tests.
St Louis, MissouriAges 12–17 - NCT05383742RecruitingPhase 2
Compare 6- vs 9-month treatment for tuberculous meningitis
This Phase 2 study tests whether a shorter, stronger 6-month set of medicines works as well as the usual 9-month regimen for tuberculous meningitis (TB infection in the covering of the brain/spinal cord). The goal is to improve outcomes while reducing treatment time and exposure.
Porto AlegreAges 15 years+ - NCT05383911Recruiting
Sickle cell care plan choices for teens and young adults
This trial tests a way to help teens and young adults with sickle cell disease (SCD) and their caregivers actively take part in treatment decisions. It focuses on improving shared decision-making through interviews and a partner-centered approach.
Wilmington, DelawareAges 15 years+ - NCT05390918Recruiting
Trial for teen sleep and suicidal thoughts risk
This study aims to see if treating insomnia (sleep problems) can lower overall risk related to suicidal behavior in teens. You may be eligible if you’ve had both recent sleep issues and recent suicidal thoughts, with some important safety exclusions.
Columbus, OhioAges 11–18 - NCT05319353RecruitingPhase 3
Maribavir for kids with CMV after transplant
This Phase 3 trial tests maribavir (an anti-CMV medicine) in children and teens who get CMV infection after a stem cell or solid organ transplant. It aims to see whether the drug is safe and well-tolerated, and whether it can reduce the virus in the body.
Wilmington, DelawareAges Up to 17 years - NCT05334823RecruitingPhase 2
CAR T-cell treatment for CD19-positive relapsed leukemia in children
This Phase 2 trial tests pCAR-19B, a customized immune-cell treatment for children and teens with CD19-positive B-ALL that has come back or did not respond to standard therapy. If eligible, you would receive the cell infusion after cell collection and testing to make sure the leukemia cells have the right marker.
Beijing, Beijing MunicipalityAges 3–21 - NCT05336201RecruitingPhase 2
Brain training program for teens with sickle cell disease
This Phase 2 study tests a cognitive (thinking) training program to help teens with sickle cell disease prepare for the changes in their care as they grow older. It may help with skills like learning, attention, and planning for transition to adult care.
Birmingham, AlabamaAges 10–18 - NCT05336084Recruiting
Study how sleep timing affects mood and thinking in teens
This study looks at how your body clock and sleep “pressure” affect reward feelings and thinking control. It may help researchers understand teen sleep patterns and how they connect to brain and behavior.
Pittsburgh, PennsylvaniaAges 13–18 - NCT05287126RecruitingPhase 2
Etrasimod for teens with active ulcerative colitis
This trial tests whether etrasimod can improve ulcerative colitis (UC) symptoms in adolescents with moderate to severe, active disease. It may help reduce inflammation and disease activity, especially if current treatments aren’t working well enough.
Little Rock, ArkansasAges 12–17 - NCT05235867Recruiting
Secretin to help teens with anorexia during refeeding
This trial studies whether secretin can help the body during “refeeding,” the careful process of restarting nutrition in people hospitalized for restrictive-type anorexia nervosa. It compares participants with very high vs very low urine output during refeeding to see if responses differ.
Los Angeles, CaliforniaAges 13–24 - NCT05164172RecruitingPhase 3
Eptinezumab for kids with ongoing or recurring migraine
This trial studies eptinezumab, a migraine treatment, in children and teens ages 6 to 17 who already completed an earlier migraine study. It mainly helps doctors learn whether the treatment can be continued safely and effectively over time.
New Haven, ConnecticutAges 6–17 - NCT05151718Recruiting
Study of ependymoma treatment resistance in children
This trial looks at why ependymoma can resist (be harder to treat) after radiation or treatment. It studies children who are already being followed in specific existing programs, which may help researchers find better treatment approaches in the future.
ToulouseAges Up to 25 years
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Common questions
- Are there clinical trials for adolescence?
- Yes. Clin2 currently lists 932 recruiting adolescence studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adolescence trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adolescence trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.