Clinical trials
Adult clinical trials
Below are recruiting adult clinical trials, each written for real people, not researchers. We’re tracking 3,746 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06696755RecruitingPhase 2
Study of icalcaprant for bipolar depression
This study tests an oral medication called icalcaprant for adults with bipolar I or II who are currently in a depressive episode. The goal is to see if it reduces symptoms and whether it's safe when taken alongside your usual mood stabilizer.
Huntsville, AlabamaAges 18–65 - NCT06700070RecruitingEarly Phase 1
Testing a microdose drug in solid tumors before surgery
This study tests a tiny amount of an experimental drug (PBA-0111) injected directly into tumors that will be surgically removed later. The goal is to see how the drug affects the tumor tissue, which may help guide future treatments for solid tumors like head and neck cancer, certain sarcomas, or triple-negative breast cancer.
Shreveport, LouisianaAges 18 years+ - NCT06700538RecruitingPhase 1/Phase 2
Study of an experimental drug for obesity with or without type 2 diabetes
This study tests an experimental medication called ARO-INHBE in adults with obesity, including those who also have type 2 diabetes. The goal is to see if it helps with weight loss and is safe.
CamberwellAges 18–65 - NCT06702449RecruitingPhase 1/Phase 2
UTI vaccine safety and immune response study for adults 18-64
This trial tests a new vaccine to prevent urinary tract infections (UTIs). It first checks safety and immune response in healthy adults, then in women with recent E. coli UTIs. The goal is to see if the vaccine can reduce future infections.
Lenexa, KansasAges 18–64 - NCT06694441Recruiting
Sleep, brain chemicals, and memory in older adults with insomnia
This study looks at how a brain chemical called norepinephrine affects sleep and thinking in older adults with insomnia. You may join if you are 55+, have insomnia, and are generally healthy.
Chicago, IllinoisAges 55 years+ - NCT06702553RecruitingPhase 3
Nitric oxide to reduce support after heart surgery
This trial tests whether giving nitric oxide gas during heart surgery can help patients recover faster and need less breathing and circulation support afterward. It is for people having planned heart or aortic surgery with a heart-lung machine for the first time.
Boston, MassachusettsAges 18 years+ - NCT06697600Recruiting
Supporting decisions for older adults with AML and their caregivers
This study helps older adults with newly diagnosed acute myeloid leukemia (AML) and their caregivers make informed decisions about treatment. You and a caregiver (like a family member or friend) will get extra support to talk through your options.
Birmingham, AlabamaAges 60 years+ - NCT06694506Recruiting
Health outcomes in adults with childhood growth hormone deficiency
This study follows adults who had growth hormone deficiency as children and are now part of a research registry. It aims to understand their health outcomes as they transition into adulthood.
Brussels, Woluwe-saint-lambertAges 18 years+ - NCT06704906Recruiting
Spine fusion surgery with a new bone graft material
This study tests a new bone graft material (Fibergraft BG Putty) used with a special screw system (Viper Prime) during spine fusion surgery. It is for adults with lower back problems who need 1 to 3 vertebrae fused, and who are not smokers or have a very low bone density.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06695169Recruiting
Studying smart pump and electronic health record use in hospital units
This trial looks at how nurses and hospital staff use smart infusion pumps connected to electronic health records. It aims to improve safety and reduce errors with IV medications.
San Antonio, TexasAges 20 years+ - NCT06449014Recruiting
Mini-implant palate expander for teens and adults
This study tests whether a new type of palate expander that uses small implants (mini-screws) can safely widen the upper jaw in people 16 and older. It may be an option for you if your upper jaw is too narrow, even if you have already stopped growing.
Anderlecht, Brussels CapitalAges 16 years+ - NCT05319678Recruiting
Music and voice testing in cochlear implant users
This study looks at how well cochlear implant users do musical and voice skills, including children and adults who use one or two implants. You might benefit by helping researchers understand how these skills develop and how devices work over time.
Madrid, MadridAges 6 years+ - NCT06688539RecruitingPhase 4
Quitting e-cigarettes in adults who also use cannabis
This trial tests if varenicline, a stop-smoking medication, can help people ages 18 to 40 quit e-cigarettes while also using cannabis. It's designed for regular e-cigarette users who want to quit and who use cannabis at least 10 days per month.
Charleston, South CarolinaAges 18–40 - NCT06692894Recruiting
Inflammation and Heart Risk in Myelodysplastic Syndromes
This study looks at whether certain signs of inflammation in the blood can help predict heart problems in people with myelodysplastic syndromes (MDS). If you have MDS and are generally well enough to participate, this trial may help doctors better understand and manage your risk of heart disease.
Burlington, VermontAges 18 years+ - NCT06691971Recruiting
Testing a device that detects wheezing in asthma attacks
This study is testing a device called AeviceMD that listens for wheezing—a whistling sound when breathing—to help doctors quickly spot asthma attacks. If you or your child is in the emergency room with a sudden asthma flare-up, you may be able to join.
The Bronx, New YorkAges 3 years+ - NCT06689618Recruiting
Electrical muscle stimulation exercise study for older adults
This study tests if whole-body electrical muscle stimulation exercise helps improve nerve signals to muscles in older adults. It compares older participants (65+) with younger ones (18-39) to see how this type of exercise affects muscle activation.
Columbia, MissouriAges 18 years+ - NCT06684769Recruiting
Chitosan brush and enamel proteins for gum treatment
This trial tests a new way to clean deep gum pockets at the base of molars using a chitosan brush and enamel proteins. It's for people who still have gum problems after standard treatment.
RigaAges 18 years+ - NCT06686914RecruitingPhase 1
How CBD affects driving by dose and sex
This study tests how different doses of CBD (a cannabis compound) affect driving ability in healthy adults. It looks at whether men and women react differently, and helps understand if CBD is safe to use before driving.
Morgantown, West VirginiaAges 18–30 - NCT06692400Recruiting
Suctioning, pain, and blood markers in intubated patients
This study looks at how routine suctioning of the breathing tube affects pain levels and certain substances in the blood in adults who are on a breathing machine for serious infections like flu, pneumonia, COVID, or sepsis. It may help doctors better understand and manage your comfort during this procedure.
Loma Linda, CaliforniaAges 18 years+ - NCT06683235Enrolling by invitation
Flaxseed for Type 2 Diabetes in Mexico
This trial tests if flaxseed can help control blood sugar in adults with type 2 diabetes. You may be able to join if you have diabetes that is not well-controlled and live in Oaxaca.
Oaxaca City, OaxacaAges 30–70 - NCT06688864Recruiting
App-based support for chronic pain in underserved adults
This study tests a smartphone app (EPIO) to help people with chronic pain manage their daily life. It is designed for adults who are Black and/or LGBTQ+ and face added challenges because of limited resources.
Rochester, MinnesotaAges 18 years+ - NCT06687733RecruitingPhase 1/Phase 2
Gene therapy for phenylketonuria
This trial tests a new gene therapy, NGGT002, which delivers a healthy gene to help people with phenylketonuria (PKU) manage their phenylalanine levels. It may reduce the need for strict diet control.
Bengbu, AnhuiAges 18–55 - NCT06682793RecruitingPhase 1/Phase 2
Study of A2B395 therapy for solid tumors with EGFR and HLA loss
This trial tests a new cell therapy called A2B395 for cancers that have EGFR, a protein on the cell surface, and have lost a specific marker called HLA-A*02. The therapy uses specially engineered immune cells to target and kill these cancer cells. This may help patients with colorectal, lung, head and neck, breast, kidney, or other solid tumors that are no longer responding to standard treatments.
Gilbert, ArizonaAges 18 years+ - NCT06627803Recruiting
Alcohol effects and drinking habits in young adults with friends
This study looks at how drinking with a close friend affects alcohol's effects and later drinking habits. You and your friend will participate together to help researchers understand social drinking patterns.
Los Angeles, CaliforniaAges 21–28
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Common questions
- Are there clinical trials for adult?
- Yes. Clin2 currently lists 3,746 recruiting adult studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adult trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adult trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.