Obstructive Sleep Apnea of Adult clinical trials

Sleep Apnea in Elderly

Tongue and mouth exercises for sleep apnea

This study tests if doing specific tongue and mouth exercises can help people with obstructive sleep apnea. If you have sleep apnea and are willing to pause other treatments for 3 months, you may be able to join.

Weight-loss drug for sleep apnea without CPAP

This study tests a new weight-loss medication called maridebart cafraglutide against a placebo in people with moderate to severe obstructive sleep apnea who are not using a CPAP machine. The goal is to find out if weight loss can reduce symptoms like pauses in breathing during sleep.

Treating sleep apnea to protect memory in older adults

This study tests whether treating sleep apnea can help protect memory and brain health in older adults. It involves using a CPAP machine or other treatments for sleep apnea and may include memory tests and brain scans over 2 years.

Airway changes after sleep apnea surgery

This study looks at how surgery for obstructive sleep apnea (a condition where breathing stops and starts during sleep) may affect your airway. The goal is to understand if the surgery makes it easier to manage your airway in the future.

Expanding the palate to help sleep apnea

This surgery expands the palate to treat obstructive sleep apnea caused by a narrow upper airway. It may help people with mild to moderate sleep apnea who have a specific type of airway collapse seen on a sleep-endoscopy test.

Study new sleep apnea and blood vessel function

This Phase 1 study looks at how blood vessel function is affected by obstructive sleep apnea in adults who are newly diagnosed and have not used CPAP. It may help researchers understand the early effects of sleep apnea and guide future treatments.

Breathing and sleep training for people with sleep apnea

This trial tests a comprehensive breathing and respiratory exercise program for newly diagnosed obstructive sleep apnea (OSA). It may help by improving sleep breathing and reducing apnea-related symptoms. You may be eligible if you recently learned you have OSA and meet age and health criteria.

Sleep apnea risk after dental surgery under general anesthesia

This study checks dental patients for the risk of sleep apnea before surgery and looks at whether that risk is linked to problems after general anesthesia. It may help you understand your own risk and improve safety.

Using a smartwatch to predict sleep apnea

This trial tests if a smartwatch can help predict sleep apnea in people who have symptoms like snoring or daytime sleepiness. It may offer a simpler way to identify the condition.

Maridebart Cafraglutide for sleep apnea in adults on CPAP

This study is testing whether a new medicine, called Maridebart Cafraglutide, can help people with obstructive sleep apnea who are already using a CPAP machine. The medicine may help with weight loss and potentially improve sleep apnea. Participants will either receive the medicine or a placebo (an inactive substance), and the study lasts for several months.

Nerve stimulation for adults with obstructive sleep apnea

This trial tests a device that stimulates a nerve to keep your airway open during sleep. It might help if you have moderate to severe obstructive sleep apnea and cannot use a CPAP mask.

Mouth guard study to reduce airway collapse in sleep apnea

This study tests whether using an anti-snoring mouth guard (a mandibular advancement appliance) can help keep your airway open during sleep if you have obstructive sleep apnea. If you’re referred for this kind of mouth guard, the trial will see if using it more regularly or in a specific way improves symptoms or breathing during sleep.

Sleep apnea study for Somali community adults

This study looks at obstructive sleep apnea—breathing pauses or poor breathing during sleep—in Somali community members. It aims to learn more about sleep apnea in this specific group, which can help guide better care.

Study testing obstruction patterns to guide CPAP alternatives

This study looks at how breathing passages narrow during sleep to better understand obstruction patterns. It may help people who are being considered for alternatives to CPAP (a common breathing device) for sleep-disordered breathing.

Testing how lung air volume affects airway narrowing during sleep testing

This study looks at whether changing lung air volume affects how open or blocked your upper airway is during a drug-induced sleep test (DISE). It may help guide surgical choices for people with obstructive sleep apnea (OSA).

Mouth exercises for sleep apnea with mouthguard therapy

This study tests whether specific mouth and throat exercises can help people with sleep apnea who already use a mandibular advancement device (a type of mouthguard). The goal is to see if adding exercises improves sleep and breathing.

Breathing Muscle Training for Sleep Apnea

This trial tests whether a simple breathing exercise (training the muscles you use to breathe in) can improve sleep apnea symptoms in people who already use CPAP. The goal is to see if adding this training helps you feel better or need less CPAP pressure.

Study of GLP-1 medicines after weight loss surgery

This study looks at what happens when people taking a GLP-1 medication (like Ozempic) either stop or continue it after weight loss surgery. The goal is to learn whether staying on the medicine helps with long-term weight control.

Melatonin for nighttime blood pressure in sleep apnea

This study tests whether melatonin can help lower nighttime blood pressure and improve sleep quality in people with obstructive sleep apnea who have 'non-dipping' blood pressure (blood pressure that stays high at night).

Sleep apnea treatment clustering study

This study looks at sleep recordings to group people with obstructive sleep apnea based on their unique signals. The goal is to match each person to the best treatment for them.

Studying silicone mouth tape for snoring and mild sleep apnea

This trial tests if wearing silicone tape over your mouth at night can help reduce snoring and improve mild sleep apnea. You will use the tape and report how you and your partner feel about your snoring.

Sleep apnea education and motivation program

This trial tests an educational program to help people with sleep apnea start using CPAP at home. The program is designed to motivate and guide you through the process of adapting to CPAP therapy.

New sleep apnea device study for CPAP users

This study tests a new device for sleep apnea that you can use instead of a CPAP machine. If you have moderate to severe sleep apnea and CPAP isn't working well for you, this study may help find an easier option.