Nitric oxide to reduce support after heart surgery
Part of Heart & circulation clinical trials.
This trial tests whether giving nitric oxide gas during heart surgery can help patients recover faster and need less breathing and circulation support afterward. It is for people having planned heart or aortic surgery with a heart-lung machine for the first time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You are scheduled for a planned (not emergency) heart or aortic surgery that uses a heart-lung machine
- You have not had open heart surgery before
- You do not have severe heart failure or need major support like a balloon pump or ventilator before surgery
- You do not have advanced kidney disease (on dialysis or with very low kidney function)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether giving nitric oxide gas through a breathing tube can improve oxygen levels in patients with severe obesity who are on a ventilator. It may help those whose lungs are struggling due to acute respiratory failure.
This study tests whether giving nitric oxide gas through a breathing tube helps people with a lung condition called ARDS (acute respiratory distress syndrome) recover and leave the intensive care unit sooner. It may help some patients with mild-to-moderate cases who need a ventilator and a central line.
This study tests whether inhaled nitric oxide—a gas that helps relax blood vessels—can prevent kidney injury in patients at high risk during heart surgery. If it works, it could reduce serious kidney complications after surgery.
This trial studies whether giving nitric oxide during heart-lung bypass surgery can help protect a baby’s brain and kidneys. If you qualify, the study team will check outcomes after surgery to see if benefits happen compared with usual care.
This Phase 3 study tests whether not giving nitric oxide during heart-lung bypass in newborns helps reduce the risk of acute kidney injury. It focuses on newborns having heart surgery for congenital heart disease.
This study tests whether two noninvasive breathing/oxygen treatments after cardiac surgery help improve heart function. It may benefit people with weak pumping function who are recovering in the hospital and can safely use these devices.
Hear when a new Nitric Oxide trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.