Clinical trials
Adult clinical trials
Below are recruiting adult clinical trials, each written for real people, not researchers. We’re tracking 3,742 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05452694Recruiting
Personalized pain relief after back fusion surgery
This trial tests a personalized plan to manage pain after lumbar (lower back) fusion and decompression surgery. It may help reduce difficult pain while guiding safe use of opioids around the time of surgery.
Pittsburgh, PennsylvaniaAges 18–99 - NCT05465174RecruitingPhase 2
Tovorafenib for children and young adults with craniopharyngioma
This trial studies tovorafenib to treat craniopharyngioma in children and young adults. It aims to shrink the tumor or slow its growth, and to learn which patients benefit most and what side effects to expect.
Birmingham, AlabamaAges 1–39 - NCT05461092RecruitingEarly Phase 1
Nerve blocks to improve pain control after spinal fusion
This early-stage study tests whether a regional nerve block can improve pain control and recovery for older adults having elective lumbar spinal fusion. If you qualify, you may receive a special pain-control injection during surgery to reduce opioid needs and improve recovery comfort.
Iowa City, IowaAges 65 years+ - NCT05463263RecruitingPhase 1/Phase 2
Study drug for adults with relapsed or treatment-resistant lymphomas
This Phase 1/2 study tests dencatistat (STP938) to treat adults whose B-cell or T-cell lymphoma has come back or not responded to treatment. It looks at safety, the best dose, and whether it can shrink tumors or improve disease control when standard options have not helped.
Denver, ColoradoAges 18 years+ - NCT05468255Recruiting
Study how stopping exercise affects blood sugar and blood vessels
This study looks at what happens to blood sugar levels and blood vessel health when active adults stop exercising. It may help doctors understand how quickly these changes can happen and who may be most affected.
Norfolk, VirginiaAges Any age - NCT05481502Recruiting
Study looks at immune markers after cell therapy
This study collects immune and tumor-related samples to learn what predicts response to adoptive cell therapy (a treatment using immune cells). If you (or your child) are eligible, you may help researchers understand who benefits and why.
Villejuif, Val De MarneAges 2 years+ - NCT05483374Recruiting
Head and neck cancer registry for adult patients
This study builds a European database (registry) of adults with certain head and neck cancers to better understand how these cancers are diagnosed and treated over time. It may help future care by collecting real-world information, rather than testing a new medicine.
Brno, BrnoAges 18 years+ - NCT05490472RecruitingPhase 1/Phase 2
Study drug for advanced solid tumors that stopped responding
This early study tests a new medicine (JAB-2485) in adults with advanced solid tumors (cancers that have spread or grown locally). You may join to see if it can shrink tumors or control the disease when other treatments haven’t worked or weren’t tolerated.
Detroit, MichiganAges 18 years+ - NCT05491551Recruiting
Alcohol training program to help you cut back or quit
This study tests a structured training program for young adults who’ve been drinking heavily, to help them reduce drinking or quit. You’ll be asked to complete daily short check-ins and follow study instructions, and you may be randomly assigned to different parts of the program.
Berkeley, CaliforniaAges 18–26 - NCT05492513Recruiting
Constraint therapy for adults with mild arm weakness after stroke
This study tests a therapy that focuses on using your weaker arm more after a stroke by “constraining” the better arm during training. It may help improve how you move and use your hand and wrist in daily life if you still have mild movement and can participate in clinic sessions.
Birmingham, AlabamaAges 18 years+ - NCT05499741Recruiting
Heat-based therapy to improve sleep in adults with Tourette’s
This trial tests a forehead temperature-regulating therapy to help improve insomnia symptoms in adults who have Tourette’s (and significant tics). It may help you sleep better by testing whether changing forehead temperature can improve sleep quality and efficiency.
Los Angeles, CaliforniaAges 18–50 - NCT05503485Recruiting
Group or phone support for older adults with distress
This study tests whether structured group therapy, or supportive phone calls, can help older adults (75+) who feel increased psychological distress. You may be placed in a group session or offered phone support, and the study will compare your experience and outcomes.
GothenburgAges 75 years+ - NCT05505500Recruiting
Parent and patient interviews for childhood kidney swelling
This study uses interviews to understand how swelling from nephrotic syndrome affects daily life for children and their caregivers. It may help researchers design better care by capturing the patient and parent perspective.
Ann Arbor, MichiganAges 2 years+ - NCT05516277Recruiting
Insomnia care study for older adults with PTSD
This study tests a treatment plan for insomnia (trouble sleeping) in older adults who also have post-traumatic stress disorder (PTSD). The goal is to see whether improving sleep also supports heart and metabolic health (such as blood sugar and heart-related measures).
North Hills, CaliforniaAges 50 years+ - NCT05518578RecruitingPhase 2
Drug trial for hard-to-control focal epilepsy with brain scar
This Phase 2 trial tests SPN-817 in adults whose seizures are still not well controlled despite trying multiple seizure medicines. It targets people with a specific type of brain finding called focal cortical dysplasia and looks at safety/tolerability and seizure outcomes over several weeks.
Jacksonville, FloridaAges 18–70 - NCT05519475RecruitingPhase 2
Gene-silencing medicine trial for adults with MASH and liver scarring
This Phase 2 study tests a gene-silencing treatment to improve chronic liver disease called MASH, especially in people with certain genetic risk. You may be eligible if you have MASH with moderate-to-advanced scarring and specific test results, and if other liver causes and recent substance/alcohol issues don’t apply.
Chandler, ArizonaAges 18–75 - NCT05522075Recruiting
Reducing Blood Pressure in Adults Who Binge Drink
This study looks at ways to lower blood pressure in adults ages 50–64 who drink little, moderate, or binge drink. It may help by testing an approach that supports healthier blood pressure in midlife.
Arlington, TexasAges 50–64 - NCT05523505Recruiting
Noninvasive brain stimulation to improve adult reading understanding
This study tests whether a safe, non-drug brain stimulation approach can help adults better understand what they read. It aims to see if the treatment improves reading comprehension and related thinking skills.
Nashville, TennesseeAges 18–40 - NCT05525923Recruiting
Personalized pain plan after chest surgery in adults
This trial tests a personalized (tailored) plan to manage pain after thoracic (chest) surgery. It may help improve comfort and recovery by matching pain treatment to your situation after surgery.
Pittsburgh, PennsylvaniaAges 18–99 - NCT05535855RecruitingPhase 1
UCD19 CAR T for adult ALL with MRD in remission
This early-phase study tests a personalized immune-cell treatment (CAR T) for adults with B-cell acute lymphoblastic leukemia (ALL) who still have tiny amounts of cancer detectable by a special test called MRD. It aims to improve outcomes for people who are in first remission but not completely “cancer-free” by MRD testing.
Aurora, ColoradoAges 18 years+ - NCT05538871Recruiting
Testing body movement and physical capacity in scoliosis adults
This study checks how well people can move and perform physical tasks if they have scoliosis (an uneven spine), or if they’re a healthy comparison group. It may help researchers better understand how body structure and function are affected by different types of scoliosis.
Edmonton, AlbertaAges 18 years+ - NCT05540613Recruiting
Tai Chi versus exercise to help thinking in mild memory loss
This study compares Tai Chi with conventional exercise to improve thinking and memory in older adults who have mild cognitive impairment. If you qualify, you may be asked to do a supervised exercise program and be tested on thinking abilities over time.
Hong KongAges 50 years+ - NCT05545007Recruiting
Pre-op vs post-op focused radiation for large brain metastases
This study compares giving focused, high-dose radiation before surgery versus after surgery for people with large brain metastases. The goal is to see which timing works best to control the tumors and help neurological outcomes.
Brescia, BresciaAges 18 years+ - NCT05556928Recruiting
Cancer and aging study for adults with blood cancers
This study builds a registry to learn how aging and “resilience” relate to outcomes in people with blood cancers. You may be asked to complete questionnaires during UAB visits, which can help researchers better understand needs in older adults.
Birmingham, AlabamaAges 50 years+
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Common questions
- Are there clinical trials for adult?
- Yes. Clin2 currently lists 3,742 recruiting adult studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adult trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adult trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.