Clinical trials
Adult clinical trials
Below are recruiting adult clinical trials, each written for real people, not researchers. We’re tracking 3,742 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05353530RecruitingPhase 1
CAR T cell treatment for CD70-positive newly diagnosed glioblastoma
This trial tests a customized immune-cell treatment (CAR T cells) for adults with newly diagnosed glioblastoma (GBM) whose tumors have enough CD70 protein. If you qualify, the goal is to see whether this treatment can better control the cancer by targeting it in the brain.
Gainesville, FloridaAges 18–80 - NCT05355272RecruitingPhase 2
Growth hormone treatment for Gulf War illness with low growth hormone
This Phase 2 study tests whether replacing growth hormone can improve symptoms in veterans with Gulf War Illness and adult growth hormone deficiency. It also checks that the treatment is safe for people with stable medications and hormone regimens.
Houston, TexasAges 18–64 - NCT05361174RecruitingPhase 1/Phase 2
Testing an IOV-4001 infusion for advanced melanoma or lung cancer
This trial studies how well and how safely an infusion called IOV-4001 works in adults with advanced melanoma or non-small-cell lung cancer that cannot be removed with surgery. It also aims to see what side effects occur and whether the treatment can help control the cancer.
Los Angeles, CaliforniaAges 18–70 - NCT05361733RecruitingPhase 1
Safety and blood-drug study of XFB19 in healthy adults
This Phase 1 study tests whether XFB19 is safe and tolerable in healthy adults and how the drug moves through the body (what the blood levels look like). You would be in the study to help researchers understand early safety and dosing information.
Knoxville, TennesseeAges 18–55 - NCT05363319Recruiting
Cemiplimab study in adults with advanced lung cancer
This observational study looks at how well cemiplimab works and how safe it is for adults with advanced non-small cell lung cancer in everyday care in Europe. It mainly follows patients already prescribed cemiplimab, and asks them to complete questionnaires.
Klagenfurt, CarinthiaAges 18 years+ - NCT05365581RecruitingPhase 1
Study drug for stomach and pancreatic cancers with lab-checked targets
This Phase 1 trial tests ASP2138 alone or with other cancer medicines in adults with stomach (including GEJ) or pancreatic cancer. You may be eligible if your tumor has a specific protein marker and your health tests and scan results meet safety requirements.
Orange, CaliforniaAges 18 years+ - NCT05371613RecruitingPhase 2/Phase 3
Testing tividenofusp alfa vs idursulfase for MPS II
This trial compares a new treatment (tividenofusp alfa) to the current standard treatment (idursulfase) in children and young adults with MPS II. It’s looking to see which option works better and is safe, especially based on age and whether the disease affects the brain.
Oakland, CaliforniaAges 2–25 - NCT05372640RecruitingPhase 1
Drug combo trial for rare cancers with shared NUT features
This Phase 1 trial tests the safety and early signs of effectiveness of combining two anti-cancer drugs (ZEN003694 and abemaciclib) in teens and adults with metastatic or unresectable NUT carcinoma, breast cancer, and other solid tumors. It may help by finding a safer dose and whether the drug combination can shrink or control tumors that do not respond to standard treatments.
Los Angeles, CaliforniaAges 12 years+ - NCT05383911Recruiting
Sickle cell care plan choices for teens and young adults
This trial tests a way to help teens and young adults with sickle cell disease (SCD) and their caregivers actively take part in treatment decisions. It focuses on improving shared decision-making through interviews and a partner-centered approach.
Wilmington, DelawareAges 15 years+ - NCT05383742RecruitingPhase 2
Compare 6- vs 9-month treatment for tuberculous meningitis
This Phase 2 study tests whether a shorter, stronger 6-month set of medicines works as well as the usual 9-month regimen for tuberculous meningitis (TB infection in the covering of the brain/spinal cord). The goal is to improve outcomes while reducing treatment time and exposure.
Porto AlegreAges 15 years+ - NCT05392894RecruitingPhase 3
Transplant using a half-matched donor for severe sickle cell
This trial tests whether a half-matched (haploidentical) blood stem cell transplant can treat adults with severe sickle cell disease. It may help reduce serious complications and improve survival, but it requires a fit health status and specific donor and medical conditions.
LondonAges 18 years+ - NCT05394987Recruiting
Testing new glasses and vision function in amblyopia adults
This study looks at how changing your glasses prescription affects vision and visual function in adults with amblyopia (often called “lazy eye”). It may help researchers understand which optical correction best supports clearer, more balanced vision.
Waterloo, OntarioAges 18–39 - NCT05404906RecruitingPhase 2/Phase 3
Azacytidine plus venetoclax to prevent AML coming back
This trial studies azacytidine (AZA) plus venetoclax as maintenance treatment to help keep acute myeloid leukemia (AML) in first remission. It may help delay or prevent AML from returning in younger adults who cannot get a stem cell transplant right away.
Suzhou, JiangsuAges 18–64 - NCT05413278Recruiting
Helps teens with inherited metabolism conditions move to adult care
This study tests a targeted approach to help teenagers with inherited metabolism conditions successfully transfer from children’s to adult healthcare. It may help families feel more confident and reduce problems during the handoff to adult services.
ViennaAges 14–25 - NCT05418868RecruitingPhase 1
Long-acting cabotegravir injection safety in healthy adults
This Phase 1 study tests how the body handles a long-acting (slow-release) cabotegravir injection combined with a drug called hyaluronidase. It also checks safety and side effects in healthy adults to help future HIV-prevention or treatment plans.
Orlando, FloridaAges 18–55 - NCT05419076RecruitingPhase 2
SRS radiation for small cell lung cancer with brain spread
This Phase 2 trial tests a type of focused radiation (stereotactic radiosurgery, or SRS) for people with small cell lung cancer that has spread to the brain. It looks at whether this approach can treat brain metastases when the cancer has limited to a certain number of spots.
Basking Ridge, New JerseyAges 18 years+ - NCT05419960Recruiting
Hearing and balance testing for teens with osteogenesis imperfecta
This study checks how well the inner ear and balance system work in children and young adults with osteogenesis imperfecta (OI). The goal is to better understand hearing and balance issues that can affect daily life.
ParisAges 12–20 - NCT05421325RecruitingPhase 2
Vaccine-like immune treatment to prevent lung infections in seniors
This Phase 2 study tests a site-specific immune “booster” in people age 65 and older to help improve natural immunity and reduce respiratory (lung/airway) infections. You may be eligible if you can consent, are in an eligible living situation, and are not currently using certain immune-suppressing medicines.
Burnaby, British ColumbiaAges 65 years+ - NCT05428228Recruiting
Hydration drink study in healthy adults
This study tests two new hydration drink formulas to see how well they rehydrate healthy adults. It’s mainly about measuring how your body responds after drinking the study products during visits.
Memphis, TennesseeAges 18–35 - NCT05428345Recruiting
Shot of vedolizumab skin injection for active bowel inflammation
This study tests whether a weekly/regular skin injection version of vedolizumab can help adults with moderate to severe ulcerative colitis or Crohn’s disease who did not fully respond to other treatments or TNF blockers. It may help by moving you from an intravenous (IV) infusion to a self/clinic injection option.
Goyang-si, Gyeonggi-doAges 18 years+ - NCT05442515RecruitingPhase 1/Phase 2
CAR T-cell treatment for hard-to-treat B-cell cancers in youth
This trial tests a personalized immune-cell therapy (CAR T cells) made to attack B-cell cancers that have come back or did not respond to prior treatment. It aims to see how well the treatment works and how safe it is in children and young adults.
Bethesda, MarylandAges 3–39 - NCT05443737RecruitingPhase 3
Telehealth care to protect fertility in young people with cancer
This trial tests a telehealth (video/phone) program that helps adolescents and young adults with cancer plan for future fertility. It may help you get support and options for preserving your ability to have children before cancer treatment affects it.
Duarte, CaliforniaAges birth–50 years - NCT05445583Recruiting
Technology support program for young adults with uncontrolled asthma
This study tests whether a technology-based program can help improve asthma control in young African American adults who are not currently well controlled. It may help you track symptoms and use asthma tools more consistently between clinic visits.
Tallahassee, FloridaAges 18–30 - NCT05447325Recruiting
Brain scans to study vaping to smoking risk
This study uses brain imaging to better predict who might start smoking cigarettes and who might increase nicotine use among young adult e-cigarette (vaping) users. It may help researchers find early warning signals so support can be targeted sooner.
Athens, GeorgiaAges 18–29
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Common questions
- Are there clinical trials for adult?
- Yes. Clin2 currently lists 3,742 recruiting adult studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adult trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adult trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.