Clinical trials
Advanced or Metastatic Breast Cancer clinical trials
Below are recruiting advanced or metastatic breast cancer clinical trials, each written for real people, not researchers. We’re tracking 6,090 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06992687Enrolling by invitationPhase 1/Phase 2
Study of HB0052 for advanced solid tumors
This trial tests a new drug called HB0052 for people with advanced solid tumors that have stopped responding to standard treatments. It aims to see if the drug is safe and effective for various cancer types.
BeijingAges 18 years+ - NCT06989398Recruiting
ASCEND supervisor training for Dutch small businesses
This trial tests a training program for supervisors in Dutch companies with 10–250 employees. It aims to improve supervisor skills and employee well-being.
AmsterdamAges 18 years+ - NCT06986421Recruiting
How stroke patients and staff feel about high-tech rehab tools
This study listens to both stroke patients and the rehab staff who care for them. It asks about their thoughts and feelings about high-tech rehab tools like robots and virtual reality, whether they've used them or not.
HyèresAges 18 years+ - NCT06984146RecruitingPhase 2
Nivo40-AVD for advanced Hodgkin lymphoma
This trial tests a combination of nivolumab and chemotherapy (AVD) for people newly diagnosed with advanced classic Hodgkin lymphoma. The goal is to see if adding nivolumab improves treatment outcomes.
MoscowAges 18 years+ - NCT06972615RecruitingPhase 2
Bladder chemo plus pembrolizumab for BCG-treated cancer
This trial tests a combination of chemotherapy placed directly into the bladder and an immunotherapy drug called pembrolizumab (given through a vein) for people with high-risk bladder cancer that has not completely responded to or has returned after BCG treatment.
CABAAges 18 years+ - NCT06973902Recruiting
A study on heart pump therapy and stress echo for advanced heart failure
This trial tests how well a heart stress ultrasound (dobutamine echo) can predict if you will get better from a special heart device called cardiac contractility modulation (CCM). CCM is a pacemaker-like implant for people with advanced heart failure who still have symptoms even with the best medicines. The study will help doctors know which patients benefit the most from this device.
Marcianise, CampaniaAges 18 years+ - NCT06977503Recruiting
Electrical stimulation with life coaching for burnout in healthcare workers
This study tests whether a gentle electrical headband used at home, plus online life coaching, can help reduce burnout symptoms in healthcare workers. You would attend three in-person visits and join group coaching sessions over about 15 weeks.
Buffalo, New YorkAges 21–75 - NCT06981325RecruitingPhase 2
Cemiplimab for advanced basal cell carcinoma
This trial tests cemiplimab, an immunotherapy drug, as a first treatment for advanced basal cell carcinoma that cannot be removed with surgery or radiation. The goal is to see if it can shrink or control the cancer.
ErfurtAges 18 years+ - NCT06974604RecruitingPhase 2
Mouthwash to prevent mouth sores from Datopotamab deruxtecan
This trial tests if a dexamethasone mouthwash can prevent painful mouth sores (stomatitis) caused by the cancer drug Datopotamab deruxtecan (Dato-DXd). It's for people with certain types of advanced lung or breast cancer who have already tried other treatments.
Providence, Rhode IslandAges 18 years+ - NCT06974370RecruitingPhase 2
Avoiding brain radiation when chemo or other drugs work
This trial tests whether some people with brain metastases from solid tumors can safely skip radiation if their cancer drugs (like targeted therapy, immunotherapy, or certain chemotherapies) shrink the brain tumors. You will get MRI scans to see if the drugs are working.
Burlington, VermontAges 18 years+ - NCT06971614RecruitingPhase 2
T3011 for bladder cancer not responding to standard treatments
This trial tests a drug called T3011 for a type of bladder cancer that hasn't responded to standard treatments like BCG or chemotherapy. It aims to see if T3011 can help shrink the cancer or keep it from growing, offering a new option for people who have limited choices.
Queen Creek, ArizonaAges 18 years+ - NCT06965374Recruiting
Study of a new Parkinson's injection and quality of life
This study is looking at how a new continuous 24-hour injection treatment (foslevodopa/foscarbidopa) affects quality of life in people with advanced Parkinson's disease. It is a real-world study, meaning you just take the medication as your doctor prescribes, and researchers observe the results.
Troina, EnnaAges 18 years+ - NCT06970639RecruitingPhase 3
Study comparing new targeted drug plus chemo vs osimertinib for lung cancer with brain tumors
This trial tests a new targeted therapy called furmonertinib combined with chemotherapy against the current standard osimertinib for people with a specific type of non-small cell lung cancer (NSCLC) that has spread to the brain. It aims to find a better treatment option for patients whose cancer cells have a common EGFR mutation.
Guangdong, GuangzhouAges 18 years+ - NCT06970171Enrolling by invitation
Willingness to use a sleep apnea mouthpiece
This trial tests how well people accept a mouthpiece (mandibular advancement device) to treat obstructive sleep apnea (a condition where your breathing stops and starts during sleep). If you have sleep apnea and can wear a device that moves your lower jaw forward while you sleep, you may be able to join.
Greifswald, Mecklenburg-VorpommernAges 18–75 - NCT06964568RecruitingPhase 3
Chemoradiation followed by immunotherapy for esophageal cancer
This trial tests a treatment for locally advanced esophageal cancer. You'll receive chemoradiation (chemo plus radiation) followed by a maintenance drug (a PD-1 inhibitor) to help prevent the cancer from coming back.
ShanghaiAges 18 years+ - NCT06967324Recruiting
Tailored support for advanced COPD with flare-ups
This study tests a personalized care program for people with advanced COPD who have had a flare-up in the last year. It aims to improve quality of life and reduce symptoms by offering extra support at home.
HvidovreAges 65 years+ - NCT06971640Recruiting
ADHD and sleep study for kids ages 6-9
This study looks at how sleep patterns relate to ADHD symptoms and thinking skills in children. It helps find out if a child's internal clock (circadian rhythm) might be delayed.
Durham, North CarolinaAges 6–9 - NCT06954467RecruitingPhase 2
Two immunotherapy drugs for advanced liver cancer
This study tests two new immunotherapy drugs (JS207 and JS007) as a first treatment for advanced liver cancer. It might be an option if you have not had any prior cancer medicine and your liver tumor is not blocking the main portal vein.
Hefei, AnhuiAges 18 years+ - NCT06957626Recruiting
Predicting polyp return after removal
This study aims to develop a tool using gut bacteria and metabolites to predict if high-risk colon polyps will come back after removal. If you are between 40 and 75 and have had certain types of colon polyps removed, you may be able to help us build better prediction methods.
BeijingAges 40–75 - NCT06957015Recruiting
New system to measure polyp size during colonoscopy
This trial tests a new computer system that helps doctors estimate the size of polyps during a colonoscopy. It may help doctors make better decisions about your treatment.
ShatinAges 18 years+ - NCT06956248Recruiting
Access to new treatments for advanced solid tumors
This trial offers access to experimental or non-standard cancer treatments for people with advanced solid tumors who have run out of standard options. The goal is to find new ways to treat cancers that are hard to manage.
SingaporeAges 21–99 - NCT05170503RecruitingPhase 2
Immunotherapy plus chemo before surgery for junction stomach cancers
This Phase 2 study tests giving immunotherapy together with chemotherapy before surgery for certain “locally advanced” cancers at the esophagus-stomach junction. It may help shrink the tumor and improve outcomes by treating the cancer earlier with both immune and chemotherapy approaches.
Guangzhou, GuangdongAges 18–75 - NCT06309836Recruiting
Study of advanced basal cell carcinoma in patients
This study looks at how people with advanced basal cell carcinoma (a type of skin cancer that is hard to treat or has spread) are cared for and what happens over time. It does not test any new treatments, but helps doctors learn more about the disease.
Roma, ITAAges 18 years+ - NCT06648733Recruiting
Better medication safety when leaving the hospital for palliative care
This trial studies how to improve medication management when patients with advanced illnesses move from hospital care to home care in Muenster. It aims to make the switch smoother and safer for people who need palliative (comfort-focused) treatment.
Münster, North Rhine-WestphaliaAges 18 years+
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Common questions
- Are there clinical trials for advanced or metastatic breast cancer?
- Yes. Clin2 currently lists 6,090 recruiting advanced or metastatic breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a advanced or metastatic breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a advanced or metastatic breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.