Clin2
NCT06970639Possibly a fitRecruiting

Study comparing new targeted drug plus chemo vs osimertinib for lung cancer with brain tumors

NSCLC Patients With Brain Metastasis

Treatments studied

Part of Brain & nervous system, Cancer, Lungs & breathing clinical trials.

This trial tests a new targeted therapy called furmonertinib combined with chemotherapy against the current standard osimertinib for people with a specific type of non-small cell lung cancer (NSCLC) that has spread to the brain. It aims to find a better treatment option for patients whose cancer cells have a common EGFR mutation.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
380 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have a type of lung cancer called non-squamous non-small cell lung cancer that has spread to the brain.
  • Your cancer cells have an EGFR mutation (either exon 19 deletion or L858R).
  • You have not had any prior cancer treatment for advanced or metastatic lung cancer.
  • You are at least 18 years old and in generally good health (able to take care of yourself).
  • You have at least one brain tumor and one tumor outside the brain that can be measured on scans.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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