Clinical trials
Aged clinical trials
Below are recruiting aged clinical trials, each written for real people, not researchers. We’re tracking 1,305 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06507189Recruiting
How exercise affects older adults: a study
This study looks at how different older adults respond to exercise. It will help researchers understand why some people benefit more than others. You will be asked to do supervised exercise sessions and tests over about 6 months.
Pensacola, FloridaAges 60 years+ - NCT07482176RecruitingPhase 3
Gene therapy trial for wet age-related macular degeneration
This trial tests a one-time gene therapy injection (IXO-vec) for people with wet age-related macular degeneration (nAMD). It aims to reduce the need for frequent eye injections by helping the eye make its own medicine to block the growth of harmful blood vessels.
Mesa, ArizonaAges 50 years+ - NCT03178149RecruitingPhase 1
Study of a new eye treatment for dry macular degeneration
This Phase 1 trial tests the safety and side effects of ASP7317 in older adults whose central vision is worsening from dry age-related macular degeneration (geographic atrophy). If you qualify, you would receive treatment in the study eye and be closely monitored for about a year.
Phoenix, ArizonaAges 50 years+ - NCT03577041Recruiting
Cost study of eye injections for new macular degeneration
This study evaluates the cost-effectiveness of three anti-VEGF eye injection treatments (bevacizumab, ranibizumab, or aflibercept) for patients with newly diagnosed age-related macular degeneration affecting the center of vision. The research aims to understand which treatment option provides the best medical and financial value in France.
AmiensAges 18–70 - NCT03821623RecruitingPhase 2
Vitamin-like nicotinamide riboside for higher blood pressure
This trial tests whether nicotinamide riboside can improve elevated blood pressure and blood vessel stiffness in middle-aged and older adults. You may be randomly assigned to take the study medicine or not, and the team will check your heart/blood vessel measurements over time.
Boulder, ColoradoAges 50 years+ - NCT03896529Recruiting
Study how aging and stress affect memory navigation
This study uses brain imaging (MRI) and controlled stimulation to understand how normal aging and stress affect memory and thinking, including how people navigate. It may help researchers learn what changes in the brain happen over time and with stress.
Atlanta, GeorgiaAges 65–80 - NCT03949647Recruiting
Study bone marrow samples from healthy adults every two years
This study collects bone marrow samples to look at healthy “bone marrow cells” and how they may change with aging. It may help researchers better understand aging biology by comparing samples over time.
Baltimore, MarylandAges 18–120 - NCT03954899Recruiting
Melatonin test for brain health in older adults
This study tests whether taking 5 mg of melatonin can improve thinking and brain health over time in older adults with early, mild symptoms. You may help researchers learn which brain changes and measures improve with melatonin.
Iowa City, IowaAges 56–85 - NCT04284397RecruitingEarly Phase 1
Study of safe temperature conditions for adults
This early study looks at which hot or cold environments are safest and most challenging for adults who don’t have symptoms of disease. It may help improve safety guidelines so older adults can exercise or be exposed to temperature changes more safely.
University Park, PennsylvaniaAges 18 years+ - NCT04330287Recruiting
Study of heart health in adults aging with HIV
This study looks at how aging affects heart health in people who have HIV. It may help researchers find better ways to prevent or monitor heart problems over time.
Essen, NordrheinwestfalenAges 18 years+ - NCT04339764RecruitingPhase 1/Phase 2
iPS cell eye transplant for dry macular degeneration
This early-phase study tests whether transplanting lab-made retinal cells from your own body can slow vision loss from geographic atrophy caused by dry age-related macular degeneration. It involves eye surgery and frequent follow-up to check safety and early signs of benefit.
Baltimore, MarylandAges 55–95 - NCT04413994Recruiting
Exclusive breast milk study in preterm babies
This study tests whether feeding extremely preterm babies only human milk (no formula) affects early health outcomes, including risks that may develop later. It also includes term-born babies for comparison. The study is mainly about feeding and safety, and you would follow the study’s feeding plan.
Innsbruck, TyrolAges 1 day–5 years - NCT04659824Recruiting
MRI study of iron buildup in normal aging
This study uses special MRI scans to measure how iron builds up in the brain as people age. It may help researchers understand what iron changes mean for healthy (non-disease) aging.
LilleAges 18–95 - NCT04792554Recruiting
Study of aging around major non-heart surgery
This study looks at changes in health and function in older adults before and after major surgery. It may help doctors understand how “aging” affects recovery and what could improve outcomes.
SingaporeAges 65–100 - NCT04796545Recruiting
Implant study for late macular degeneration with cataracts
This post-market study looks at how well a telescope-like eye implant (NG SI IMT 3X) works for people with very advanced age-related macular degeneration that affects the center of vision, plus cataracts. The implant is placed in one eye, and you’ll get training to learn how to use it after surgery.
BrusselsAges 55 years+ - NCT07443826RecruitingPhase 1/Phase 2
Gene therapy for age-related muscle loss and heart health
This trial tests a gene therapy that may help rebuild muscle and improve blood vessel growth in people ages 35 to 75. It's designed for those with stable health conditions and no history of cancer, heart disease, blood clots, or diabetes.
Coxen Hole, Bay IslandsAges 35–75 - NCT02604563Recruiting
Aging, blood changes, and health in older adults
This study examines why some older adults develop changes in their blood cells that may affect their health. Researchers will look for links between these blood changes, aging, and common health problems in older people.
St Louis, MissouriAges 50 years+ - NCT07160179RecruitingPhase 1/Phase 2
Study of an eye injection for geographic atrophy
This study tests a new medicine (ABBV-6628) given as an injection into the eye to see how well it works and how it moves through the body for people with geographic atrophy (an advanced form of dry age-related macular degeneration). It may help slow vision loss from this condition.
Carmel, IndianaAges 50 years+ - NCT05028309Recruiting
Study how obesity affects breathing and exercise in older adults
This study compares how body weight (higher or lower body fat) affects lung function, breathing during exercise, and exercise capacity in adults ages 65–75. You may be asked to do lung and exercise testing, but only if you meet health and activity restrictions.
Dallas, TexasAges 65–75 - NCT05043753Recruiting
Ultrasound screening for abnormal baby growth late in pregnancy
This trial studies whether a specific ultrasound approach can better detect problems with fetal (baby) growth in the later part of pregnancy. It may help identify concerns earlier so your care team can plan the next steps.
Modena, ModenaAges 18–45 - NCT05048680Recruiting
Breathing low-oxygen training to support brain blood flow in seniors
This study tests whether brief “low-oxygen” conditioning can improve blood flow to the brain and overall cerebrovascular (brain blood vessel) health in older adults. It may help people who are generally less active, as long as they have no major medical or safety barriers for the training.
La Tronche, Auvergne-Rhône-AlpesAges 60–80 - NCT05149742Recruiting
Study of hearing loss and thinking skills in midlife adults
This study looks at how severe hearing loss affects thinking and memory in adults aged 45–64. Researchers will compare people with significant hearing loss to people with normal hearing who are similar in age, sex, and education.
ParisAges 45–64 - NCT05197270RecruitingPhase 1/Phase 2
Study drug 4D-150 for wet macular degeneration not responding enough
This early-stage study tests 4D-150 (a one-time injection into the eye) for “wet” age-related macular degeneration to see if it can better control leaking blood vessel growth and reduce fluid. It’s for people who are already getting anti-VEGF injections but still need ongoing treatment because of signs of fluid on special eye scans.
Phoenix, ArizonaAges 50 years+ - NCT05296980Recruiting
Testing a dementia risk-reduction program for older adults
This study checks whether a program called REMINDER can help reduce risk of developing dementia by improving risk factors over 12 weeks. It’s for older adults who have higher dementia risk but do not currently have dementia.
CoimbraAges 60–75
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Common questions
- Are there clinical trials for aged?
- Yes. Clin2 currently lists 1,305 recruiting aged studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aged trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aged trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.