Clinical trials
Alcohol Use clinical trials
Below are recruiting alcohol use clinical trials, each written for real people, not researchers. We’re tracking 262 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06593652Recruiting
How caregivers can help teens with alcohol use
This study looks at how involving caregivers in a brief talk with a primary care provider might help teens who are drinking alcohol or using other substances. It aims to find better ways to support teens and their families.
Indianapolis, IndianaAges 12–17 - NCT06559995RecruitingPhase 2/Phase 3
Ketone drink for alcohol withdrawal
This study tests whether a special ketone drink can ease alcohol withdrawal and help your brain heal. If you have been drinking heavily for at least 3 years and are having withdrawal symptoms now, this might be an option for you.
Philadelphia, PennsylvaniaAges 18–65 - NCT06493773Recruiting
Alcohol help for new liver disease diagnosis
This trial tests a program to help people recently diagnosed with alcohol-related liver disease cut back on drinking. If you qualify, you may get support to improve your liver health.
Køge, KøgeAges 18 years+ - NCT06405607RecruitingPhase 2
Psilocybin vs Ketamine for Alcohol Use Disorder Trial
This trial tests two psychedelic-assisted therapies, psilocybin and ketamine, to see which works better for reducing heavy drinking in people with alcohol use disorder (AUD). You'll receive either drug along with counseling, and the study monitors safety closely.
Iowa City, IowaAges 21–65 - NCT06269627RecruitingPhase 4
Brain activity study for alcohol use treatment
This trial tests how the medication acamprosate affects brain activity in people with moderate to severe alcohol use disorder. It may help researchers understand how this treatment works.
Bethesda, MarylandAges 21–65 - NCT06259916Recruiting
EEG to tell alcohol vs. cannabis intoxication
This study uses electroencephalography (EEG) to see if brain activity can tell whether you are drunk, high, or both. Results might help improve safety in the future.
Fort Collins, ColoradoAges 21–50 - NCT06070649RecruitingPhase 1
DMT for Alcohol Use Disorder
This trial tests whether a single dose of DMT, a psychedelic, can help people with alcohol use disorder. It's a small early-phase study to see if the treatment is safe and promising.
New Haven, ConnecticutAges 21–65 - NCT05855668Recruiting
Study how brain and behavior differ in alcohol and cannabis use
This study looks at how people’s thoughts, brain-related measures, and behaviors differ between alcohol use disorder and cannabis use disorder. You may be asked to join group psychotherapy and complete assessments, which could help improve how care is planned for people like you.
Toronto, OntarioAges 18 years+ - NCT05677321Recruiting
Study how taste and smell differ in alcohol use disorder
This study compares how people with alcohol use disorder and people without it experience taste and smell. It also checks brain activity during taste/smell testing to understand individual differences that may be linked to alcohol use.
Bethesda, MarylandAges 18–65 - NCT05486234Recruiting
Study to reduce cannabis and alcohol use with teen and caregiver
This study looks at ways to help teens cut down on cannabis and alcohol use. You may qualify if you’ve been using both in the last three months and your caregiver is able to join and consent.
Charleston, South CarolinaAges 13–17 - NCT05389930RecruitingPhase 2
Study how cannabis affects alcohol drinking
This Phase 2 study looks at whether using cannabis changes how much alcohol you drink. You may be able to take part if you’ve been drinking heavily and using cannabis recently and can meet health and screening requirements.
Providence, Rhode IslandAges 21–50 - NCT05015881Enrolling by invitationPhase 2/Phase 3
Brain and heart scans in alcohol use disorder
This study uses special brain and heart scans to see how sugar (glucose) is used in people with alcohol use disorder compared with people without it. It may help researchers understand the brain–heart connection in alcohol use disorder.
Philadelphia, PennsylvaniaAges 21–65 - NCT04998916Recruiting
Brain stimulation to reduce heavy drinking in alcohol use disorder
This trial tests a type of noninvasive brain stimulation to see if it can reduce drinking and related “wanting” to drink. It may help people with alcohol use disorder who are currently drinking heavily.
Charleston, South CarolinaAges 21–65 - NCT04616781RecruitingPhase 2/Phase 3
Ketone drink study for alcohol use disorder brain function
This study tests whether a ketone-based treatment (a ketone ester) can change brain activity in people with alcohol use disorder who are not currently seeking treatment. You may also have brain scans, so the study is looking for safe MRI eligibility and certain health factors.
Philadelphia, PennsylvaniaAges 21–65 - NCT05408247RecruitingPhase 4
N-acetylcysteine to help people cut back on alcohol
This trial tests whether N-acetylcysteine (a supplement-like medicine) can help people with alcohol use disorder reduce or stop drinking. You may be randomly assigned to receive N-acetylcysteine or a comparison treatment, and you’ll complete interviews during the study.
Sydney, New South WalesAges 18–70 - NCT05899660Recruiting
Omega-3 for alcohol use disorder during withdrawal
This trial studies whether taking omega-3 supplements during a hospital alcohol-withdrawal program can improve recovery for people with alcohol use disorder. It may help by changing inflammation and how the body responds to stopping alcohol.
BrusselsAges 18–70 - NCT07825818RecruitingEarly Phase 1
Brain scan study for heavy drinkers
This study uses a special brain scan to look at how alcohol use affects energy production in brain cells. It may help researchers find new ways to treat alcohol use disorder.
Pittsburgh, PennsylvaniaAges 18–55 - NCT07735585Recruiting
App-based support for alcohol use disorder
This study tests a smartphone app that uses rewards to help people reduce or stop drinking. You may be eligible if you have alcohol use disorder and are seeking treatment at a specific clinic in São Paulo.
São Paulo, São PauloAges 18–70 - NCT07612631RecruitingEarly Phase 1
Brain imaging study of alcohol and stress response
This research uses brain imaging to understand how two brain systems—one involved in stress and one involved in reward—interact in people with alcohol use disorder. The goal is to find new ways to help people reduce heavy drinking.
Pittsburgh, PennsylvaniaAges 18–55 - NCT07573540Recruiting
Smart Phone App to Support Alcohol Recovery
This study tests a smartphone app called STAR designed to help people stay in recovery from alcohol use disorder. Researchers want to see if the app helps people maintain their sobriety after they've already stopped drinking.
Madison, WisconsinAges 18 years+ - NCT05102942Recruiting
Online training to improve attention for alcohol use disorder
This study tests whether an online attention-focused training program can help people with alcohol use disorder better control their attention and urges. It may offer an extra tool alongside standard primary treatment.
Valby, Capital Region of DenmarkAges 18–75 - NCT07464613Recruiting
Social thinking in severe alcohol use disorder
This study looks at how people with severe alcohol use disorder process social information, like understanding others' emotions or intentions. It uses brain imaging (MRI) and tests on a smartphone. The goal is to learn more about social cognition in recovery.
Reims, ReimsAges 18–65 - NCT05997212Recruiting
Can brain stimulation help with thinking skills in alcohol use disorder?
This study tests if a noninvasive brain stimulation technique called repetitive TMS (rTMS) can improve thinking skills like decision-making and focus in people recovering from alcohol use disorder. You must have been alcohol-free for 8 weeks to 5 years.
Querétaro City, QuerétaroAges 25–59 - NCT07219953RecruitingPhase 3
Testing brenipatide for alcohol use disorder
This study tests an experimental medicine called brenipatide to help people reduce or stop drinking. It involves getting a daily injection and completing check-ins and questionnaires over several months.
Scottsdale, ArizonaAges 18–75
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Common questions
- Are there clinical trials for alcohol use?
- Yes. Clin2 currently lists 262 recruiting alcohol use studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alcohol use trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alcohol use trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.