Clinical trials
Alcohol Use Disorder clinical trials
Below are recruiting alcohol use disorder clinical trials, each written for real people, not researchers. We’re tracking 356 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05505188Recruiting
Predicting long-term pain after head and neck radiotherapy
This study looks for ways to predict and improve pain you may have months after radiotherapy for first head and neck cancer. It may help doctors better anticipate pain and support patients during recovery.
CaenAges 18 years+ - NCT06727331RecruitingPhase 2
Tirzepatide for alcohol use recovery
This trial tests if tirzepatide, a medication that helps with appetite and blood sugar, can help people with alcohol use disorder drink less or stop drinking. You would visit the clinic regularly and receive the drug or a placebo.
Boston, MassachusettsAges 18 years+ - NCT06712602RecruitingPhase 1
Testing PT150 for Alcohol Use Disorder
This study tests whether a drug called PT150 can help people with moderate to severe alcohol use disorder who are not currently seeking treatment. You will be asked to stay abstinent from alcohol for short periods and attend sessions to see how PT150 affects your body and alcohol cravings.
Lexington, KentuckyAges 21–55 - NCT06706349Recruiting
Exercise to improve sleep in alcohol use disorder
This study tests whether a personalized exercise program can improve sleep quality in people with alcohol use disorder. You would work with a physical activity coach over several weeks, and your sleep and health would be monitored closely.
BesançonAges 18–65 - NCT06684483Recruiting
Heavy alcohol use and your mouth health
This study looks at how heavy alcohol use affects your saliva and mouth health. It compares people with alcohol use disorder to healthy volunteers to see if the heavy drinking changes the mouth's natural defenses.
Bethesda, MarylandAges 18–100 - NCT06415721Recruiting
TMS guided by brain scans for alcohol use disorder
This study uses a brain stimulation technique called TMS combined with MRI scans to treat alcohol use disorder. It aims to see if targeting specific brain connections can help reduce drinking.
Palo Alto, CaliforniaAges 25–75 - NCT06679062RecruitingPhase 2
Suvorexant for alcohol use disorder and PTSD
This study tests whether the sleep medication suvorexant can help people with both alcohol use disorder and PTSD. If you're struggling with drinking, PTSD symptoms, and poor sleep, this trial may offer a new treatment option.
Los Angeles, CaliforniaAges 21–65 - NCT06648642Recruiting
MRI-guided brain stimulation for alcohol use disorder
This study tests whether a new type of brain stimulation, guided by MRI and a robot, can help reduce heavy drinking in people with alcohol use disorder. The treatment is non-invasive and aims to improve brain function related to cravings.
San Antonio, TexasAges 18–65 - NCT04598399Recruiting
Mindfulness program for alcohol relapse prevention
This study compares two non-medication programs to help people with alcohol use disorder stay away from relapse. It tests whether mindfulness-based relapse prevention works better than relaxation meditation without a guide.
AngersAges 18 years+ - NCT06629259RecruitingPhase 2
Guanfacine for Alcohol Use Disorder
This trial tests if guanfacine, a medication that calms certain brain signals, can help people reduce or stop drinking. You may qualify if you have moderate to severe alcohol use disorder and want to quit.
Indianapolis, IndianaAges 18 years+ - NCT06620276Recruiting
Ketamine and therapy for alcohol use disorder and depression
This trial tests if combining ketamine infusions with weekly therapy can help people who have both alcohol use disorder and hard-to-treat depression. You may qualify if you drink at least moderately, have treatment-resistant depression, and are willing to attend 8 therapy sessions.
Montreal, QuebecAges 18–70 - NCT06618755Recruiting
Staying sober after detox: a coaching study
This study tests if motivational interviews after hospital detox help people with alcohol use disorder stay completely sober for one year. It might help you if you are committed to full abstinence and have a phone available.
MontpellierAges 18 years+ - NCT06593652Recruiting
How caregivers can help teens with alcohol use
This study looks at how involving caregivers in a brief talk with a primary care provider might help teens who are drinking alcohol or using other substances. It aims to find better ways to support teens and their families.
Indianapolis, IndianaAges 12–17 - NCT06584448Recruiting
Drinking, acetate, and stress study
This study looks at how acetate (a substance produced when the body breaks down alcohol) affects stress and drinking. It tests if giving acetate can help people with alcohol use disorder (AUD) reduce their drinking.
New Haven, ConnecticutAges 18–60 - NCT06479681Recruiting
Coaching help for alcohol use recovery in hospital
This trial tests if a peer recovery coach can help people with alcohol use disorder stay sober after being hospitalized. You'll get support from someone who has been through recovery themselves.
Greenville, South CarolinaAges 18–75 - NCT06552741Recruiting
Screening for substance and alcohol use studies
This study screens people with or without past or current substance or alcohol use problems. It helps the researchers see if you might qualify for other studies at the NIDA research center.
Baltimore, MarylandAges 18–99 - NCT06559995RecruitingPhase 2/Phase 3
Ketone drink for alcohol withdrawal
This study tests whether a special ketone drink can ease alcohol withdrawal and help your brain heal. If you have been drinking heavily for at least 3 years and are having withdrawal symptoms now, this might be an option for you.
Philadelphia, PennsylvaniaAges 18–65 - NCT06548490RecruitingPhase 2
Semaglutide for Opioid Use Disorder
This study tests whether a once-weekly injection of semaglutide (a GLP-1 receptor agonist) can reduce opioid use in people who are already on buprenorphine or methadone but still using opioids. It lasts about 19 weeks.
Baltimore, MarylandAges 18–75 - NCT06518785Recruiting
Ultrasound brain treatment for alcohol use disorder
This study tests if focused ultrasound can help reduce alcohol cravings by stimulating a specific part of the brain. Participants will receive ultrasound treatments and undergo an MRI to see how the brain responds.
San Francisco, CaliforniaAges 18 years+ - NCT06493773Recruiting
Alcohol help for new liver disease diagnosis
This trial tests a program to help people recently diagnosed with alcohol-related liver disease cut back on drinking. If you qualify, you may get support to improve your liver health.
Køge, KøgeAges 18 years+ - NCT06494891RecruitingPhase 2
Understanding motivation for IV alcohol drinking
This study looks at why people with alcohol use disorder choose to drink alcohol given through an IV. The goal is to better understand the motivation behind drinking, which could help improve treatments.
Los Angeles, CaliforniaAges 21–65 - NCT06426303RecruitingPhase 4
Alcohol Use Disorder Treatment in Veterans: Brain and Inflammation
This study is for veterans with alcohol use disorder who have been sober for 5 days to 3 weeks. It looks at how trauma, inflammation, and brain function relate to alcohol problems and how well treatment works. You will be in a group that gets medication or a placebo.
Portland, OregonAges 18–60 - NCT06399653Recruiting
Nerve stimulation for alcohol use disorder in veterans
This study tests a non-invasive device that gently stimulates a nerve in your neck (the vagus nerve) to see if it can help reduce alcohol cravings and improve daily functioning. It is designed for veterans who struggle with heavy drinking and want to explore a new treatment option.
San Diego, CaliforniaAges 21–65 - NCT06405607RecruitingPhase 2
Psilocybin vs Ketamine for Alcohol Use Disorder Trial
This trial tests two psychedelic-assisted therapies, psilocybin and ketamine, to see which works better for reducing heavy drinking in people with alcohol use disorder (AUD). You'll receive either drug along with counseling, and the study monitors safety closely.
Iowa City, IowaAges 21–65
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Common questions
- Are there clinical trials for alcohol use disorder?
- Yes. Clin2 currently lists 356 recruiting alcohol use disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alcohol use disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alcohol use disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.