Clinical trials
Alcohol Use clinical trials
Below are recruiting alcohol use clinical trials, each written for real people, not researchers. We’re tracking 262 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07638553RecruitingPhase 3
Psilocybin to prevent alcohol relapse with depression
This study tests whether psilocybin (a psychedelic compound) can help people with severe alcohol use disorder stay sober longer, especially if they also have depression. Participants receive guided psilocybin sessions alongside counseling to reduce the risk of returning to heavy drinking.
BayonneAges 18 years+ - NCT06319885Recruiting
Text messaging to reduce high-risk alcohol use in older adults
This study uses text messages to help adults aged 55–80 who drink above recommended limits to reduce their alcohol intake. If you want to cut back but not necessarily quit completely, this program may be a good fit for you.
Odense, Southern DenmarkAges 55–80 - NCT06371404Recruiting
Brain imaging study of stress and alcohol use disorders
This study uses a special brain scan to look at how stress and alcohol use affect the brain. It may help people with PTSD, alcohol use disorder, or healthy volunteers understand these conditions better.
New Haven, ConnecticutAges 18–70 - NCT04164940Recruiting
Tracking how hospital care affects alcohol risk in older adults
This study looks at how adults aged 21+ change over time after being admitted to the hospital for alcohol-related problems. It may help researchers understand which hospital approaches work best for reducing future alcohol-related harm—especially for people who have not had alcohol or drug use disorders before.
StavangerAges 21 years+ - NCT07447635Recruiting
Testing a program to help cancer survivors quit smoking and reduce drinking
This study tests a program (MBI) to help cancer survivors quit smoking and cut back on alcohol. It's designed for people who want to make these changes in the next 30 days.
Tampa, FloridaAges 18 years+ - NCT06326684RecruitingEarly Phase 1
Testing suvorexant for alcohol use disorder
This study tests whether the sleep medication suvorexant can help people with alcohol use disorder drink less. It involves a short stay where you'll receive either suvorexant or a placebo and then have alcohol.
Lexington, KentuckyAges 21–55 - NCT06675539Recruiting
Testing a tool to predict alcohol withdrawal severity in French speakers
This study tests a French version of a questionnaire (PAWSS) that helps doctors predict how severe alcohol withdrawal might be. It is for people aged 18 to 60 who are dependent on alcohol and planning a supervised detox or being hospitalized for another reason.
ÉtampesAges 18–60 - NCT03827460RecruitingPhase 1
Study tests how men and women respond to alcohol abstinence
This Phase 1 study looks at sex differences in how the body and brain respond when people stop drinking alcohol for a short time. You may be asked to complete questionnaires and provide blood samples to measure changes during the abstinence period.
Indianapolis, IndianaAges 21–35 - NCT06789250Recruiting
Online therapy for mental health and alcohol use issues
This trial tests an internet-based cognitive behavioral therapy program designed for people who struggle with both mental health symptoms (like depression or anxiety) and problematic alcohol use. The goal is to see if this approach can help improve both issues at the same time, conveniently from home.
LinköpingAges 18 years+ - NCT05619185Recruiting
Online program to help couples reduce risky drinking
This study tests an adaptive (tailored) online program to help service members and their partners cut down risky alcohol use. It also focuses on whether couples can practice healthier communication and coping skills while feeling safe together.
Palo Alto, CaliforniaAges 18 years+ - NCT07441603Recruiting
Lifestyle support program for hospital patients
This trial tests a proactive lifestyle program for patients admitted to the hospital. It aims to help you improve your health habits during your stay.
GreifswaldAges 18–64 - NCT07118839RecruitingPhase 2/Phase 3
MDMA therapy for veterans with PTSD and alcohol use
This study tests whether MDMA-assisted therapy can help veterans who have both PTSD and alcohol use disorder. If you have tried a standard therapy before and want to reduce or stop drinking, this treatment may offer a new option.
West Haven, ConnecticutAges 18 years+ - NCT07232641Recruiting
How pandemic rules affected opioid addiction treatment in the VA
This study looks at how changes in federal and state rules about medications for opioid use disorder during the pandemic affected veterans. It uses information already in your VA records, so there are no extra visits or tests needed.
Boston, MassachusettsAges 18 years+ - NCT07071779Recruiting
Online training to help young people resist alcohol or cocaine
This study tests a web-based training program to help teens and young adults (ages 14–35) improve their ability to say no to alcohol or cocaine. The training could make it easier to resist cravings during treatment.
BernAges 14–35 - NCT07602270Recruiting
How a Ketogenic Diet Affects Alcohol in Your Body
This study tests whether eating a ketogenic diet (very low carb, high fat) changes how your body processes alcohol. Researchers will have you follow a special diet and then measure your body's response to controlled amounts of alcohol in a lab setting.
Philadelphia, PennsylvaniaAges 21–50 - NCT06084520Recruiting
Pain questionnaire study for opioid and non-opioid patients
This study tests two questionnaires for people with long-term pain. Researchers want to see if the tools work well for both those taking opioids and those who are not. Your answers can help improve pain care.
Uppsala, UpplandAges 18–75 - NCT06959342Recruiting
Brain stimulation to reduce cravings in alcohol use disorder
This trial tests if a gentle brain stimulation technique (tDCS) can help people with alcohol use disorder control their cravings and drinking habits. It is an add-on to your regular treatment.
MannheimAges 18–65 - NCT06771843Recruiting
Helping men with HIV reduce drinking and improve HIV prevention
This study tests whether helping men with HIV who also drink heavily can lower their alcohol use and improve how well HIV treatment works to prevent passing the virus to others. It's for men living in fishing communities in Uganda.
KampalaAges 18 years+ - NCT06484075RecruitingPhase 1/Phase 2
Sleep medication for alcohol use disorder
This study tests whether suvorexant, a sleep aid, can help people with alcohol use disorder by looking at brain changes. It may improve sleep and reduce drinking.
Bethesda, MarylandAges 18–75 - NCT05365347Recruiting
Program to reduce risky alcohol use in early psychosis
This study tests an intervention aimed at helping people with early psychosis who also drink in a risky way. It may help reduce problematic drinking during a critical early period of illness.
Halifax, Nova ScotiaAges 16–35 - NCT07485036Recruiting
Study on mood and alcohol use in new mothers
This study looks at how new mothers feel emotionally, including mood, alcohol use, and symptoms of depression. By participating, you can help researchers understand the challenges mothers face in the first year after childbirth.
Chicago, IllinoisAges 18 years+ - NCT06835907Recruiting
Baclofen for anxiety and alcohol use disorder
This trial tests if baclofen can help people with both anxiety and alcohol use disorder. It is an open-label study, meaning everyone knows they are taking the medication. Researchers want to see if it supports people in staying alcohol-free.
Jette, Brussels CapitalAges 18–65 - NCT07214207RecruitingPhase 2
Testing a sleep medicine for alcohol use disorder and stress-related drinking
This trial tests whether a medicine called suvorexant, which is used for sleep, can help people with alcohol use disorder drink less, especially when stressed. You would receive the medicine or a placebo, and researchers will track your drinking and stress levels over several weeks.
Columbus, OhioAges 18–65 - NCT05959434RecruitingPhase 2
Therapy program to reduce drinking relapse and PTSD symptoms
This Phase 2 study tests a combined therapy approach for people who have both alcohol use disorder and post-traumatic stress disorder (PTSD). It aims to help you process stressful memories and lower the chances of relapse back to heavy drinking.
Charleston, South CarolinaAges 18 years+
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Common questions
- Are there clinical trials for alcohol use?
- Yes. Clin2 currently lists 262 recruiting alcohol use studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alcohol use trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alcohol use trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.