Clinical trials
Alcohol Use clinical trials
Below are recruiting alcohol use clinical trials, each written for real people, not researchers. We’re tracking 282 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07573540Recruiting
Smart Phone App to Support Alcohol Recovery
This study tests a smartphone app called STAR designed to help people stay in recovery from alcohol use disorder. Researchers want to see if the app helps people maintain their sobriety after they've already stopped drinking.
Madison, WisconsinAges 18 years+ - NCT07612631RecruitingEarly Phase 1
Brain imaging study of alcohol and stress response
This research uses brain imaging to understand how two brain systems—one involved in stress and one involved in reward—interact in people with alcohol use disorder. The goal is to find new ways to help people reduce heavy drinking.
Pittsburgh, PennsylvaniaAges 18–55 - NCT05821634Enrolling by invitation
Personalized telehealth counseling for anxiety and alcohol use
This study personalizes how telehealth counseling is delivered for people dealing with anxiety or trauma-related symptoms and alcohol use problems. It may help by tailoring counseling timing and approach to what you need.
Piscataway, New JerseyAges 18–65 - NCT05855031Recruiting
Liver care support for people getting alcohol-use treatment
This trial looks at liver-focused care for people receiving outpatient treatment for alcohol dependence or alcohol-related harmful drinking. It may help by checking and improving how your liver health is supported while you stay in alcohol-use treatment.
KøgeAges 18–110 - NCT07559500RecruitingPhase 1
Study of tirzepatide for alcohol use disorder
This trial tests if tirzepatide, a diabetes drug, affects brain chemistry linked to alcohol use. Researchers want to see if it can help people with mild-to-moderate alcohol use disorder who also have tried stimulants.
Bethesda, MarylandAges 21–65 - NCT04135846RecruitingPhase 2
Alpha-blocker medicine to help reduce alcohol drinking
This Phase 2 trial tests whether blocking certain body signals (alpha receptors) with a study medicine can help people with alcohol use disorder cut down or stop drinking. You may be able to join if you meet alcohol-use criteria and can safely take the study drug.
Providence, Rhode IslandAges 18 years+ - NCT05042102RecruitingPhase 2
Donepezil plus brain training for alcohol use disorder
This Phase 2 study tests whether donepezil, along with structured cognitive (brain) training, can improve outcomes for people with alcohol use disorder. It will measure whether this combination helps after recent heavy drinking, while tracking safety over about 13 weeks.
West Haven, ConnecticutAges 18–80 - NCT05732207Recruiting
Study of brain changes in alcohol use disorder
This study looks at whether alcohol use disorder affects the cerebellum, a part of the brain involved in movement and balance. It may help researchers understand brain impacts and guide better treatments.
Baltimore, MarylandAges 25–55 - NCT05807139RecruitingPhase 1
Spironolactone for alcohol use disorder
This Phase 1 study tests whether spironolactone (a medicine that affects salt and hormone balance) is safe and potentially helpful in people with alcohol use disorder. You may be eligible if you are currently drinking heavily, have low alcohol withdrawal symptoms, and meet several lab and medication safety rules.
Baltimore, MarylandAges 21–99 - NCT06090422RecruitingPhase 1/Phase 2
Ketamine for depression and alcohol use disorder
This trial tests if ketamine can help people who have both depression and alcohol use disorder. You must be currently sober, have at least moderate depression, and be admitted to the hospital for addiction treatment.
TromsøAges 18–65 - NCT06160232RecruitingPhase 2
Psilocybin therapy for severe alcohol use disorder
This trial tests whether psilocybin, a psychedelic substance, combined with talk therapy can help people with severe alcohol use disorder stop or reduce drinking. Participants will first complete a 4-week inpatient detox program before receiving psilocybin in a supervised setting.
BrusselsAges 21–64 - NCT06286774Recruiting
Sleep and alcohol treatment study
This study tests whether improving sleep through cognitive behavioral therapy (CBT-I) can help reduce heavy drinking in people with both alcohol use disorder and insomnia. It might be a good fit if you have trouble sleeping and drink heavily.
Columbia, MissouriAges 18–49 - NCT06479681Recruiting
Coaching help for alcohol use recovery in hospital
This trial tests if a peer recovery coach can help people with alcohol use disorder stay sober after being hospitalized. You'll get support from someone who has been through recovery themselves.
Greenville, South CarolinaAges 18–75 - NCT06629259RecruitingPhase 2
Guanfacine for Alcohol Use Disorder
This trial tests if guanfacine, a medication that calms certain brain signals, can help people reduce or stop drinking. You may qualify if you have moderate to severe alcohol use disorder and want to quit.
Indianapolis, IndianaAges 18 years+ - NCT06648642Recruiting
MRI-guided brain stimulation for alcohol use disorder
This study tests whether a new type of brain stimulation, guided by MRI and a robot, can help reduce heavy drinking in people with alcohol use disorder. The treatment is non-invasive and aims to improve brain function related to cravings.
San Antonio, TexasAges 18–65 - NCT06853912RecruitingPhase 2
Psilocybin therapy for PTSD and alcohol use in veterans and first responders
This trial tests whether psilocybin, given along with psychological support, can help military veterans and first responders who have both PTSD and alcohol use disorder. If you're a veteran or first responder looking to reduce or stop drinking, you may be able to participate.
Seattle, WashingtonAges 21–65 - NCT07279558RecruitingPhase 2
CBD and Alcohol Use Study
This study tests whether cannabidiol (CBD), a compound from cannabis, can help people who drink alcohol regularly reduce their drinking or change their drinking patterns. You may be eligible if you're 21-65, have used CBD or cannabis before, drink alcohol regularly, and don't take certain medications that could interfere.
Aurora, ColoradoAges 21–65 - NCT07413458Recruiting
VR nature for alcohol use disorder
This trial tests whether using virtual reality (VR) nature scenes can help people with alcohol use disorder who also have depression. You'll be in an intensive outpatient program and may try VR sessions to see if they reduce cravings and improve mood.
Ann Arbor, MichiganAges 18 years+ - NCT06173973Enrolling by invitationPhase 2/Phase 3
Ketone supplement for alcohol withdrawal symptoms
This study tests whether a special supplement (ketones) can help people feel better during alcohol withdrawal. It is for adults who are already in a treatment program for alcohol withdrawal.
Philadelphia, PennsylvaniaAges 18–75 - NCT02108054Recruiting
Building and testing tasks to measure brain and movement
This study helps create and test simple tasks that measure brain function and movement in people with different backgrounds. It may help researchers better understand how the brain and body work, which can improve future alcohol-related treatments.
Bethesda, MarylandAges 18–65 - NCT05576350Recruiting
Coaching to reduce risky drinking and HIV risk
This study tests an intervention (coaching/skills training) to help reduce risky alcohol use and reduce behaviors that increase HIV risk. It may help you if you drink in an at-risk way and may benefit from HIV prevention like PrEP.
New Haven, ConnecticutAges 18–35 - NCT04957628Recruiting
Tailored interventions for people in hospital medical wards
This study tests whether personalized (tailored) interventions can help patients during their hospital stay in medical wards. You may be invited to participate if you can understand the study information and your stay is for a medical issue, not a major injury or planned surgery.
OsloAges 18 years+ - NCT07059078Recruiting
Talk therapy with or without mindfulness for teen drinking
This study tests whether a brief talk therapy session, sometimes combined with mindfulness exercises, can help teens reduce alcohol use. It is designed for teens who get care at Johns Hopkins and already drink alcohol at least once a month.
Baltimore, MarylandAges 12–17 - NCT05372029Recruiting
Study of animal-assisted therapy for alcohol use disorder
This trial studies whether animal-assisted therapy can help Veterans with alcohol use disorder, especially early after quitting or reducing alcohol. It may help with cravings or staying stable, but you must meet specific health and safety requirements.
San Diego, CaliforniaAges 18–65
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Common questions
- Are there clinical trials for alcohol use?
- Yes. Clin2 currently lists 282 recruiting alcohol use studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alcohol use trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alcohol use trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.