Clinical trials
Alcoholism clinical trials
Below are recruiting alcoholism clinical trials, each written for real people, not researchers. We’re tracking 527 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06584448Recruiting
Drinking, acetate, and stress study
This study looks at how acetate (a substance produced when the body breaks down alcohol) affects stress and drinking. It tests if giving acetate can help people with alcohol use disorder (AUD) reduce their drinking.
New Haven, ConnecticutAges 18–60 - NCT06494891RecruitingPhase 2
Understanding motivation for IV alcohol drinking
This study looks at why people with alcohol use disorder choose to drink alcohol given through an IV. The goal is to better understand the motivation behind drinking, which could help improve treatments.
Los Angeles, CaliforniaAges 21–65 - NCT06318975Recruiting
Text messaging to prevent alcohol problems in air force
This study tests whether text messages can help prevent problem drinking among Air Force Technical Training students. It compares different ways of texting to see which works best.
San Antonio, TexasAges 18 years+ - NCT06326684RecruitingEarly Phase 1
Testing suvorexant for alcohol use disorder
This study tests whether the sleep medication suvorexant can help people with alcohol use disorder drink less. It involves a short stay where you'll receive either suvorexant or a placebo and then have alcohol.
Lexington, KentuckyAges 21–55 - NCT06307964Recruiting
Gut bacteria in alcoholic hepatitis
This trial is looking at bacteria inside the liver of people with alcoholic hepatitis. It may help understand how these bacteria affect the disease and lead to better treatments.
LyonAges 18 years+ - NCT06259916Recruiting
EEG to tell alcohol vs. cannabis intoxication
This study uses electroencephalography (EEG) to see if brain activity can tell whether you are drunk, high, or both. Results might help improve safety in the future.
Fort Collins, ColoradoAges 21–50 - NCT06136195RecruitingPhase 1
Mavoglurant for alcohol craving in heavy drinkers
This trial tests whether a medication called mavoglurant can reduce alcohol cravings and drinking in people who are heavy drinkers with alcohol use disorder and are not looking for treatment.
New Haven, ConnecticutAges 21–50 - NCT06138821Recruiting
Endoscopic sleeve gastroplasty for obesity and MASH
This study tests if a procedure called endoscopic sleeve gastroplasty helps people with obesity and a liver condition called MASH lose weight and improve their liver health. It might be an option if you have both obesity and MASH and haven't had weight-loss surgery before.
Boston, MassachusettsAges 18 years+ - NCT06002633Recruiting
Alcohol effects and brain responses in PTSD
This study explores how people with PTSD respond to alcohol and how their brains handle approach or avoidance situations. You may participate if you drink alcohol occasionally and are between 21 and 60 years old.
Austin, TexasAges 21–60 - NCT05287711Recruiting
Motivational alcohol support to help prevent partner violence
This study tests an extra (adjunct) counseling approach to reduce harmful alcohol use in Veterans enrolled in the Strength at Home program. The goal is to help prevent intimate partner violence (IPV), especially when alcohol is involved.
Boston, MassachusettsAges 18 years+ - NCT05786157Recruiting
Couples alcohol and safety support for drinking and relationship harm
This study tests a patient-focused approach to help couples where alcohol misuse and relationship physical harm may be happening. You may be asked to take part in sessions focused on safety, coping, and relationship communication, and some components may include controlled alcohol exposure.
Charleston, South CarolinaAges 21 years+ - NCT05766761Recruiting
Support to reduce alcohol during pregnancy
This study aims to help reduce alcohol use in pregnancy by offering support or testing an approach for people who’ve had alcohol recently. It may help you lower the risk to your pregnancy by focusing on alcohol exposure.
Houston, TexasAges 18 years+ - NCT05728697Recruiting
Test a liver ultrasound method to measure fat and stiffness
This trial tests a special ultrasound technique during an endoscopy to see how well it can detect changes in the liver from non-alcoholic fatty liver disease. It may help improve non-invasive assessment before or alongside a follow-up liver biopsy.
Boston, MassachusettsAges 18 years+ - NCT05699018Recruiting
Screening people with liver scarring in primary care
This study tests how well primary care doctors can screen for advanced liver scarring in people with fatty liver from non-alcohol causes or from alcohol use. It may help find liver problems earlier so you can get the right follow-up.
AngersAges 40–80 - NCT05619185Recruiting
Online program to help couples reduce risky drinking
This study tests an adaptive (tailored) online program to help service members and their partners cut down risky alcohol use. It also focuses on whether couples can practice healthier communication and coping skills while feeling safe together.
Palo Alto, CaliforniaAges 18 years+ - NCT05522075Recruiting
Reducing Blood Pressure in Adults Who Binge Drink
This study looks at ways to lower blood pressure in adults ages 50–64 who drink little, moderate, or binge drink. It may help by testing an approach that supports healthier blood pressure in midlife.
Arlington, TexasAges 50–64 - NCT05241990Recruiting
Help improve alcohol care for people with HIV in clinics
This study tries a practical clinic strategy to help HIV clinics better offer and carry out alcohol treatment. You may be able to join if you work at the clinic or if you have HIV and your alcohol use screening shows possible unhealthy drinking.
San Diego, CaliforniaAges 18 years+ - NCT05015881Enrolling by invitationPhase 2/Phase 3
Brain and heart scans in alcohol use disorder
This study uses special brain and heart scans to see how sugar (glucose) is used in people with alcohol use disorder compared with people without it. It may help researchers understand the brain–heart connection in alcohol use disorder.
Philadelphia, PennsylvaniaAges 21–65 - NCT04946851Enrolling by invitation
Alcohol use study for adults who join the NIAAA screening
This study uses a brain-and-behavior “assessment” (neuroclinical testing) to better understand addiction. You may be tested only if you are an adult and are enrolled in the NIAAA screening program, and you cannot join if you are acutely intoxicated.
Bethesda, MarylandAges 18–99 - NCT04781322RecruitingPhase 1
Study drug to reduce LDL cholesterol effects in heavy drinkers
This Phase 1 study tests how safe a cholesterol-lowering antibody (alirocumab) is in people who drink heavily but are not seeking alcohol treatment. It also looks at early drug effects in the body to see how it might change cholesterol-related signals.
Bethesda, MarylandAges 21–65 - NCT04666402Recruiting
Testing better ways to diagnose early liver disease
This study looks at integrated diagnostic tests to find early liver problems sooner. It may help you (if referred to the community liver clinic) get more timely information about what’s going on.
Manchester, Greater ManchesterAges 18 years+ - NCT04395196RecruitingPhase 2
Prenatal choline for pregnancy after alcohol exposure
This trial tests whether taking a choline supplement during pregnancy can reduce harmful effects on the baby when a person drinks heavily while pregnant. It may help support healthier pregnancy and baby outcomes for those who meet the study’s drinking and nutrition criteria.
Cape Town, Western CapeAges 18–45 - NCT03884075RecruitingPhase 2
Semaglutide study for fatty liver and how sugar affects the liver
This Phase 2 study tests how semaglutide (a diabetes medication also used for weight) affects fatty liver and the liver’s response to sugar. It may help people with non-alcoholic fatty liver disease understand whether the drug improves liver fat and related changes.
Bethesda, MarylandAges 18–100 - NCT03845205Recruiting
Liver transplant timing study for alcohol-related liver disease
This study compares early versus standard liver transplant timing for people whose liver illness was caused by alcohol use. It looks at treatment outcomes to see which approach helps patients do better.
Baltimore, MarylandAges 18 years+
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Common questions
- Are there clinical trials for alcoholism?
- Yes. Clin2 currently lists 527 recruiting alcoholism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alcoholism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alcoholism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.