Clinical trials
Alzheimer's Disease Dementia clinical trials
Below are recruiting alzheimer's disease dementia clinical trials, each written for real people, not researchers. We’re tracking 459 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07250113Enrolling by invitation
WeCareToFeedDysphagia study for care partners of older adults
This trial tests a program to help care partners of older adults with Alzheimer's disease and swallowing problems. It aims to reduce stress and improve care at home.
Manhasset, New YorkAges 18 years+ - NCT06855368Recruiting
Biomarkers for tracking dementia progression
This study looks at biological markers to monitor how dementia changes over time. It may help understand the disease better in people with early Alzheimer's or mild cognitive impairment.
RomaAges 18 years+ - NCT07306598Recruiting
PET imaging for tau-related brain diseases
This trial uses a special imaging agent called [18F]NIDF to take pictures of tau protein clumps in the brain, which are linked to Alzheimer's and other memory or movement disorders. It may help doctors see these changes more clearly.
Hefei, AnhuiAges 18–90 - NCT06723015Enrolling by invitationPhase 2
Tau PET in anti-amyloid therapy for Alzheimer's
This study uses brain scans to see how anti-amyloid treatments affect tau protein buildup in people with early Alzheimer's. If you have mild cognitive impairment or mild Alzheimer's, you may be eligible to help understand how these treatments work.
Rochester, MinnesotaAges 50–90 - NCT07262645RecruitingPhase 3
Light therapy for mild to moderate Alzheimer's disease
This study tests a near-infrared light therapy device for people with mild to moderate Alzheimer's disease. It may help with memory and thinking by using light on the head, a non-invasive approach.
Beijing, Beijing MunicipalityAges 50–85 - NCT07457125RecruitingPhase 1/Phase 2
Exosome therapy for mild to moderate Alzheimer's disease
This trial tests a new drug made from stem cell exosomes (CB-Exo-A600) to see if it can help people with mild to moderate Alzheimer's disease. It aims to slow down symptoms and improve quality of life.
BeijingAges 50 years+ - NCT06651567RecruitingPhase 2
Study of ITI-1284 for agitation in Alzheimer's
This trial tests an experimental drug called ITI-1284 to see if it can reduce agitation in people with Alzheimer's disease. It may help if you or your loved one experiences significant agitation related to Alzheimer's.
Anaheim, CaliforniaAges 55 years+ - NCT06540833RecruitingPhase 2
Study of ITI-1284 for psychosis in Alzheimer's disease
This trial tests an experimental drug, ITI-1284, to see if it can safely reduce psychosis (hallucinations or delusions) in people with Alzheimer's disease. It may be an option for patients who have both Alzheimer's and related psychotic symptoms.
Anaheim, CaliforniaAges 55 years+ - NCT06094192Recruiting
Brain stimulation to improve memory in Alzheimer's
This study tests whether a gentle, noninvasive brain stimulation technique called tACS can help improve memory in people with Alzheimer's disease or mild cognitive impairment. It may also include healthy older adults for comparison.
Boston, MassachusettsAges 50–100 - NCT06362707RecruitingPhase 2
Fasudil trial for early Alzheimer's disease
This trial tests a medication called fasudil to see if it can help people with early Alzheimer's disease. It is for people who have early symptoms (mild cognitive impairment or mild dementia) and have biomarker evidence of Alzheimer's in their brain.
Tromsø, NordlandAges 50–100 - NCT06827678Recruiting
Study of Alzheimer’s disease using brain scans in China
This study uses brain imaging to understand early changes in Alzheimer's disease. It may help people with or without memory problems learn more about their condition and support future treatments.
ShanghaiAges 45–90 - NCT06120049RecruitingPhase 2/Phase 3
Comparing new PET scans for Parkinson's, MSA, Lewy body dementia, and Alzheimer's
This study tests if a new radioactive tracer called [18F]-MFBG can help doctors better distinguish between Parkinson's disease, multiple system atrophy (MSA), dementia with Lewy bodies, and Alzheimer's disease. It compares the new scan with two standard scans to see which is most accurate.
Ghent, GentAges 18–85 - NCT06418971Recruiting
Testing a caregiving support platform for dementia caregivers
This study is testing an online platform called CarePair that helps connect family caregivers of people with dementia to resources and support. It may help caregivers find the assistance they need.
Los Angeles, CaliforniaAges 18 years+ - NCT05934188Recruiting
Study how gut signals relate to brain aging and diseases
This study looks at how the gut may influence the brain in normal aging and conditions like Alzheimer’s, Parkinson’s, and multiple sclerosis. It may help researchers understand new ways to measure or treat these brain changes over time.
Venice-Lido, VeniceAges 20–90 - NCT06887192RecruitingPhase 2
Testing ML-007C-MA for Alzheimer's Psychosis
This trial tests a study drug called ML-007C-MA to see if it can safely reduce hallucinations and delusions in people with Alzheimer's disease who also have psychosis. If you or your loved one has Alzheimer's and has been experiencing false beliefs or seeing/hearing things that aren't there for at least two months, this study may be an option.
Phoenix, ArizonaAges 55–90 - NCT07033494RecruitingPhase 2
Study of MK-2214 for early Alzheimer's disease
This trial tests an experimental medicine called MK-2214 for people with early Alzheimer's (mild cognitive impairment or mild dementia). The goal is to see if it can slow memory and thinking problems.
Irvine, CaliforniaAges 50–85 - NCT07512362RecruitingPhase 2
Stem cells and antibodies for early Alzheimer's disease
This study tests whether human stem cells, combined with your existing Alzheimer's medication (Leqembi or Kisunla), can help slow memory loss and improve daily functioning in people with mild cognitive impairment or early Alzheimer's. You would receive a stem cell infusion as an add-on to your current treatment.
Miami, FloridaAges 55–90 - NCT03503331RecruitingPhase 2
Alzheimer’s imaging add-on for research center patients
This study adds special brain scans (MRI and a PET scan) for people already enrolled in the UAB Alzheimer’s Disease Center research program. The scans are used to learn more about brain changes in Alzheimer’s, which may help researchers find better ways to measure and understand the disease.
Birmingham, AlabamaAges 50 years+ - NCT06923007Recruiting
Vagus nerve stimulation for Alzheimer's disease
This trial tests if a nerve stimulation device can help people with mild to moderate Alzheimer's. It is for patients aged 50 to 80 who are on a stable medication.
BeijingAges 50–80 - NCT07040904Recruiting
Mindfulness to help older Latino adults stay mentally sharp
This study tests whether mindfulness training can help older Latino adults stay sharp as they age. Researchers will measure changes in thinking skills and brain health.
St Louis, MissouriAges 65 years+ - NCT07259499Recruiting
Predictors of emergency visits in frail older adults
This study looks at why frail older adults go to the emergency room. Researchers want to see if blood tests and brain scans can help predict who needs emergency care. Participation involves one interview and having had a recent brain scan and blood work.
Pisa, PisaAges 65 years+ - NCT07422857RecruitingPhase 3
A PET scan for detecting signs of Alzheimer's
This trial uses a new type of PET scan to look for specific proteins in the brain that are linked to Alzheimer's disease. It will help doctors see how these proteins relate to cognitive decline and compare scans from people with normal thinking to those with memory problems.
Wuhan, HubeiAges 50 years+ - NCT04360200Recruiting
Study of thinking changes in older adults
This trial looks at people over age 50 who have mild thinking or memory problems but do not have dementia by standard clinical criteria. It tests how these early changes are characterized and measured using exams such as blood tests and brain scans, which may help improve understanding and future care.
Guangzhou, GuangdongAges 50 years+ - NCT04579120Recruiting
Brain scan study in healthy aging or early Alzheimer’s
This study uses brain imaging to understand changes in the brain during normal aging and early Alzheimer’s disease (AD). It may help researchers spot early brain changes and evaluate how well imaging measures those changes.
St Louis, MissouriAges 18 years+
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Common questions
- Are there clinical trials for alzheimer's disease dementia?
- Yes. Clin2 currently lists 459 recruiting alzheimer's disease dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alzheimer's disease dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alzheimer's disease dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.