Clinical trials
Alzheimer's Disease Dementia clinical trials
Below are recruiting alzheimer's disease dementia clinical trials, each written for real people, not researchers. We’re tracking 459 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03140865Recruiting
Alzheimer’s disease research core for brain and memory testing
This study group collects detailed information from people with normal memory, mild cognitive impairment, or mild Alzheimer’s disease to support Alzheimer’s research. You may need multiple visits, brain scans, and sometimes a spinal fluid sample, with strict health and medication requirements to keep results clear.
Winston-Salem, North CarolinaAges 55 years+ - NCT06338397Recruiting
Social and emotional thinking in Alzheimer's
This study looks at how Alzheimer's disease and similar conditions affect social and emotional thinking. Researchers will use brain scans and questionnaires to understand these changes better.
LilleAges 40–85 - NCT06976203RecruitingPhase 3
Testing karxt for thinking problems in alzheimer's
This trial tests if a combination medicine, KarXT plus KarX-EC, can help with thinking and memory problems in people with mild to moderate Alzheimer's disease. It aims to see if the treatment is safe and effective.
Fullerton, CaliforniaAges 60–85 - NCT07399171RecruitingPhase 2
Testing HT-4253 to prevent Alzheimer's in APOE4 carriers
This trial tests an experimental drug called HT-4253 to see if it can prevent Alzheimer's disease in people who are at higher genetic risk (carry the APOE4 gene) and have early signs of amyloid buildup in the brain. If you qualify, you would take the drug or a placebo and be monitored over time.
Abu Dhabi, Abu Dhabi EmirateAges 50–75 - NCT07477431RecruitingPhase 2
Testing levetiracetam for those at risk of Alzheimer's
This trial tests if a medication called levetiracetam (a drug usually used for seizures) can help protect memory in people who are at higher risk for Alzheimer's but do not yet have memory problems. It involves brain scans and cognitive tests to see if the drug can reduce overactive brain activity linked to memory loss.
Toronto, OntarioAges 55–85 - NCT04123314RecruitingEarly Phase 1
Psilocybin study for depression in mild memory or early Alzheimer’s
This early-phase study tests whether psilocybin (a psychedelic substance) can help with depression in people who have mild memory problems or early Alzheimer’s. The trial also closely monitors safety, thinking changes, mood, and blood pressure before and after dosing.
Baltimore, MarylandAges 18–85 - NCT04804241RecruitingPhase 2
Senicapoc for early Alzheimer’s symptoms
This Phase 2 study tests whether the drug senicapoc can slow or improve symptoms in people with early Alzheimer’s disease or mild memory impairment. You would have a 50/50 chance of getting senicapoc or a placebo (inactive pill), along with regular study visits and testing.
Sacramento, CaliforniaAges 55–85 - NCT05405075Recruiting
Alzheimer’s research study with brain tests and blood samples
This study supports Alzheimer’s research by collecting health and thinking (cognitive) test results and blood samples to study genetics and biomarkers. You may be enrolled if you’re age 40 or older and can do these checkups, even if you have mild memory problems or dementia.
Phoenix, ArizonaAges 40 years+ - NCT05516667Recruiting
Study of Alzheimer’s patients and their families
This study follows people with Alzheimer’s disease and family members over 2 years. It uses regular questionnaires and medical checkups to better understand needs and health changes for patients and caregivers.
France, MarseilleAges 18 years+ - NCT06385951Recruiting
Virtual reality navigation test for early Alzheimer's detection
This study uses a virtual reality navigation task to detect early signs of Alzheimer's disease. It compares people with mild cognitive problems, mild Alzheimer's, and healthy older adults to see if this test can spot the disease earlier.
Ghent, East-FlandersAges 50–80 - NCT06669182Recruiting
Cerebellar TMS for Alzheimer's Disease
This trial uses a non-invasive brain stimulation technique (TMS) to target the cerebellum in people with Alzheimer's disease. It aims to see if this treatment can improve symptoms and cognitive function.
Xi'an, ShaanxiAges 50–85 - NCT06741553Recruiting
Studying lecanemab for early Alzheimer's disease
This study looks at how well lecanemab works for people with early Alzheimer's disease. It aims to see if the drug can help slow down memory and thinking problems.
Hangzhou, ZhejiangAges Up to 85 years - NCT07073066Recruiting
Lymphatic surgery for Alzheimer's disease (CLEAN-AD trial)
This trial tests a surgical procedure that connects lymphatic vessels in the neck to help clear waste from the brain in people with moderate-to-severe Alzheimer's disease. The goal is to see if this can improve thinking and memory.
Dongguan, GuangdongAges 50–80 - NCT07598617Recruiting
Testing a New Computer Memory Assessment for Early Cognitive Changes
This study evaluates a new computer-based test to detect early memory and thinking changes before they progress to dementia. Researchers are looking for adults 65+ who've noticed subtle cognitive changes in the last 5 years to help refine and test this assessment tool.
Plymouth, DevonAges 65 years+ - NCT06733714Recruiting
Brain stimulation plus memory training for older adults
This study tests whether a gentle, non-invasive electrical current applied to the scalp (tACS) combined with computer-based brain exercises can improve memory and thinking in older adults who have concerns about their cognitive health.
Rio de Janeiro, Rio de JaneiroAges 50 years+ - NCT06792877Recruiting
Mindfulness for thinking in early Alzheimer's
This study tests if mindfulness training can help protect thinking and memory in early-stage Alzheimer's disease. It compares mindfulness to other activities to see if it slows down memory loss.
Boston, MassachusettsAges 50–100 - NCT06803784Recruiting
Bioproducts in body fluids for early brain disease detection
This study is looking for proteins in blood and other body fluids that could help detect brain diseases like Parkinson's, Alzheimer's, and ALS early. It aims to improve diagnosis and future treatments.
Pozzilli, ItalyAges 20 years+ - NCT07303998Recruiting
Brain stimulation and chair yoga for knee pain in Alzheimer's
This study tests two treatments together for people with Alzheimer's who also have chronic knee pain: a gentle brain stimulation (tDCS) and online chair yoga. The goal is to see if these can reduce knee pain and improve daily life.
Tucson, ArizonaAges 60 years+ - NCT02022943Recruiting
Join an Alzheimer's prevention registry website
This trial builds a registry so researchers can contact you about future Alzheimer’s studies. It mainly requires agreeing to the registry’s website terms and conditions.
Phoenix, ArizonaAges 18–110 - NCT05733520Recruiting
Telehealth coaching for Alzheimer’s caregivers using a phone
This trial tests a mobile telehealth program designed to help unpaid caregivers reduce Alzheimer’s-related symptoms in the people they care for. If you’re a primary caregiver, you may get study sessions using a smartphone or similar device.
Indianapolis, IndianaAges 18 years+ - NCT07202494Recruiting
Brain aging and resilience MRI study
This study uses powerful MRI scans to understand how the brain ages and why some people stay healthy while others develop neurological diseases like multiple sclerosis or Alzheimer's. It compares healthy volunteers to people with certain conditions, and all participants get a detailed brain MRI.
MarseilleAges 18–90 - NCT07216716Recruiting
Health app recommendation tool for Alzheimer's caregivers
This study tests a tool that helps find health apps for people caring for a loved one with Alzheimer's or a related dementia. It aims to see if the tool makes it easier to choose useful apps for your caregiving journey.
Pittsburgh, PennsylvaniaAges 18–65 - NCT05800028Recruiting
Study brain scans and social life in memory changes
This study looks at how memory and brain function relate to social interactions. It focuses on people with probable Alzheimer’s disease or a specific language-related condition, and on healthy partners matched by age and social background.
CaenAges 18–85 - NCT06411561Recruiting
Boosting memory after ICU stay for older adults
This study tests a combination of activities (like cognitive training and exercise) to help older adults recover thinking and memory after a serious illness in the ICU. It may help you regain sharpness and independence after leaving the intensive care unit.
Seattle, WashingtonAges 60 years+
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Common questions
- Are there clinical trials for alzheimer's disease dementia?
- Yes. Clin2 currently lists 459 recruiting alzheimer's disease dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alzheimer's disease dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alzheimer's disease dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.